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Research Grade Lacutamab

Catalog #:   DHE43801 Specific References (55) DATASHEET
Host species: Humanized
Isotype: IgG1-kappa
Applications: Research Grade Biosimilar
Expression system: Mammalian Cells
Overview

Catalog No.

DHE43801

Expression system

Mammalian Cells

Species reactivity

Human

Host species

Humanized

Isotype

IgG1-kappa

Clonality

Monoclonal

Applications

Research Grade Biosimilar

Target

CD158K, MHC class I NK cell receptor, NKAT4, Natural killer-associated transcript 4, KIR3DL2, p70 NK receptor CL-5, CD158k, p70 natural killer cell receptor clone CL-5, CD158 antigen-like family member K, Killer cell immunoglobulin-like receptor 3DL2, NKAT-4

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P43630

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Alternative Names

IPH4102, CAS: 2187368-16-5

Clone ID

Lacutamab

Note

For research use only. Not suitable for clinical or therapeutic use.

Data Image
  • SDS-PAGE
    SDS PAGE for Lacutamab
  • SEC-HPLC
    The purity of this product is >95% as determined by SEC-HPLC.
References

New biotherapies for the treatment of cutaneous T-cell lymphomas., PMID:35026391

KIR3DL2 contributes to the typing of acute adult T-cell leukemia and is a potential therapeutic target., PMID:35687761

Histopathological Markers for Target Therapies in Primary Cutaneous Lymphomas., PMID:37998391

Advances in the pharmacological management of cutaneous T-cell lymphoma., PMID:38828644

Therapeutic advances for Cutaneous T Cell Lymphoma., PMID:40131851

Synthesis of (±)-Bisavenanthramide B-6 by an Anionic Anhydride Mannich Reaction, PMID: 27023166

Production of muramic delta-lactam in Bacillus subtilis spore peptidoglycan, PMID: 14679227

A new lactam 28-norlimonoid from the leaves of Azadirachta indica A. Juss. (Meliaceae), PMID: 29806497

Bombyxamycins A and B, Cytotoxic Macrocyclic Lactams from an Intestinal Bacterium of the Silkworm Bombyx mori, PMID: 30801193

The permeability barrier of Haemophilus influenzae type b against beta-lactam antibiotics, PMID: 6608514

C-17 lactam-bearing limonoids from the twigs and leaves of Amoora tsangii, PMID: 24621263

Enantioselective Total Syntheses of (-)-Rhazinilam, (-)-Leucomidine B, and (+)-Leuconodine F, PMID: 26481194

Hepatic Effects of Pharmacological Doses of Hydroxy-Cobalamin[c-lactam] in Mice, PMID: 28135329

SYNTHESIS AND EVALUATION OF NEW PHTHALAZINE SUBSTITUTED β-LACTAM DERIVATIVES AS CARBONIC ANHYDRASE INHIBITORS, PMID: 26615643

Glechomanamides A-C, Germacrane Sesquiterpenoids with an Unusual Δ 8-7,12-Lactam Moiety from Salvia scapiformis and Their Antiangiogenic Activity, PMID: 31668072

Monte Carlo Simulation Methodologies for β-Lactam/β-Lactamase Inhibitor Combinations: Effect on Probability of Target Attainment Assessments, PMID: 31423601

Targeting the Nonmevalonate Pathway in Burkholderia cenocepacia Increases Susceptibility to Certain β-Lactam Antibiotics, PMID: 29439968

Current challenges in antimicrobial chemotherapy: focus on ß-lactamase inhibition, PMID: 20394454

A new lactam alkaloid from Portulaca oleracea L. and its cytotoxity, PMID: 29022744

Metallo-beta-lactamases of Pseudomonas aeruginosa--a novel mechanism resistance to beta-lactam antibiotics, PMID: 18519228

Vitamin B12: chemical modifications, PMID: 23715409

Spiro-Lactams as Novel Antimicrobial Agents, PMID: 31702503

Recent developments in carbapenems, PMID: 11922861

Synthesis of Guaianolide Analogues with a Tunable α-Methylene-γ-lactam Electrophile and Correlating Bioactivity with Thiol Reactivity, PMID: 33201697

Enhancement of bactericidal activity against group B streptococci with reduced penicillin susceptibility by uptake of gentamicin into cells resulting from combination with β-lactam antibiotics, PMID: 28341517

Optimization of Bicyclic Lactam Derivatives as NMDA Receptor Antagonists, PMID: 28218498

Binding of TEM-1 beta-lactamase to beta-lactam antibiotics by frontal affinity chromatography, PMID: 28334649

GT32-B new 20-membered macrocyclic lactam antibiotic, PMID: 9099234

A novel and efficient chromophore reaction based on a lactam-fused aza-BODIPY for polyamine detection, PMID: 33070857

[Diagnostic evaluation of β-lactam antibiotic allergy], PMID: 24988157

Azithromycin compared with beta-lactam antibiotic treatment failures in pneumococcal infections of children, PMID: 15131461

Oligoamide, a new lactam from the leaves of Angylocalyx oligophyllus, PMID: 29882428

Limitations of beta-lactam therapy for infections caused by susceptible Gram-positive bacteria, PMID: 25124369

Production of beta-lactam antibiotics and its regulation, PMID: 1815263

Saccharothrix algeriensis NRRL B-24137, the first non-Streptomyces actinobacterium, produces holomycin after cystine feeding, PMID: 32642829

Discovery of ixabepilone, PMID: 19174552

Discovery of deoxylimonin δ-lactam derivative with favorable anti-inflammation and antinociception efficacy from chemical modified limonin/deoxylimonin analogs, PMID: 32371249

Potential effect of selective pressure with different β-lactam molecules on the emergence of reduced susceptibility to β-lactams in group B Streptococci, PMID: 30632638

Self-reported beta-lactam intolerance: not a class effect, dangerous to patients, and rarely allergy, PMID: 31067139

Novel Isoxazolidine and γ-Lactam Analogues of Homonucleosides, PMID: 31698778

Evolutionary ecology of beta-lactam gene clusters in animals, PMID: 28316142

Antibacterial chemotherapy. Part One. B-lactam antibiotics, PMID: 3328607

[B-lactam antibiotics: grouping according to their chemical structure and bacteriological properties], PMID: 3333440

Total Syntheses of Bulgecins A, B, and C and Their Bactericidal Potentiation of the β-Lactam Antibiotics, PMID: 29716193

Synergistic Interactions of Indole-2-Carboxamides and β-Lactam Antibiotics against Mycobacterium abscessus, PMID: 32041716

Design, Synthesis, and Biological Investigation of Epothilone B Analogues Featuring Lactone, Lactam, and Carbocyclic Macrocycles, Epoxide, Aziridine, and 1,1-Difluorocyclopropane and Other Fluorine Residues, PMID: 32065746

Design and Investigation of Optical Properties of N-(Rhodamine-B)-Lactam-Ethylenediamine (RhB-EDA) Fluorescent Probe, PMID: 29662009

[Guides for rational use of B-lactam antibiotics:resistance mechanism and clinical interpretation], PMID: 12872552

Lactam hybrid analogues of solonamide B and autoinducing peptides as potent S. aureus AgrC antagonists, PMID: 29738955

Treatment options for extended-spectrum beta-lactamase (ESBL) and AmpC-producing bacteria, PMID: 26891857

Optical microscopy reveals the dynamic nature of B. pseudomallei morphology during β-lactam antimicrobial susceptibility testing, PMID: 32677888

Intrapartum beta-lactam antibiotics for preventing group B streptococcal early-onset disease: can we abandon the concept of 'inadequate' intrapartum antibiotic prophylaxis?, PMID: 31762370

An update on adverse drug reactions related to β-lactam antibiotics, PMID: 29633867

Past and Present Perspectives on β-Lactamases, PMID: 30061284

β-Lactamases and β-Lactamase Inhibitors in the 21st Century, PMID: 30959050

Datasheet

Document Download

Research Grade Lacutamab.pdf

 

$ 530
Product specifications
1 mg 530 5 mg 1590 25 mg 4130

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For research use only. Not for human or drug use.

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Research Grade Lacutamab [DHE43801]
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