Catalog No.
DHE43801
Expression system
Mammalian Cells
Species reactivity
Human
Host species
Humanized
Isotype
IgG1-kappa
Clonality
Monoclonal
Applications
Research Grade Biosimilar
Target
CD158K, MHC class I NK cell receptor, NKAT4, Natural killer-associated transcript 4, KIR3DL2, p70 NK receptor CL-5, CD158k, p70 natural killer cell receptor clone CL-5, CD158 antigen-like family member K, Killer cell immunoglobulin-like receptor 3DL2, NKAT-4
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P43630
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names
IPH4102, CAS: 2187368-16-5
Clone ID
Lacutamab
Note
For research use only. Not suitable for clinical or therapeutic use.
New biotherapies for the treatment of cutaneous T-cell lymphomas., PMID:35026391
KIR3DL2 contributes to the typing of acute adult T-cell leukemia and is a potential therapeutic target., PMID:35687761
Histopathological Markers for Target Therapies in Primary Cutaneous Lymphomas., PMID:37998391
Advances in the pharmacological management of cutaneous T-cell lymphoma., PMID:38828644
Therapeutic advances for Cutaneous T Cell Lymphoma., PMID:40131851
Synthesis of (±)-Bisavenanthramide B-6 by an Anionic Anhydride Mannich Reaction, PMID: 27023166
Production of muramic delta-lactam in Bacillus subtilis spore peptidoglycan, PMID: 14679227
A new lactam 28-norlimonoid from the leaves of Azadirachta indica A. Juss. (Meliaceae), PMID: 29806497
Bombyxamycins A and B, Cytotoxic Macrocyclic Lactams from an Intestinal Bacterium of the Silkworm Bombyx mori, PMID: 30801193
The permeability barrier of Haemophilus influenzae type b against beta-lactam antibiotics, PMID: 6608514
C-17 lactam-bearing limonoids from the twigs and leaves of Amoora tsangii, PMID: 24621263
Enantioselective Total Syntheses of (-)-Rhazinilam, (-)-Leucomidine B, and (+)-Leuconodine F, PMID: 26481194
Hepatic Effects of Pharmacological Doses of Hydroxy-Cobalamin[c-lactam] in Mice, PMID: 28135329
SYNTHESIS AND EVALUATION OF NEW PHTHALAZINE SUBSTITUTED β-LACTAM DERIVATIVES AS CARBONIC ANHYDRASE INHIBITORS, PMID: 26615643
Glechomanamides A-C, Germacrane Sesquiterpenoids with an Unusual Δ 8-7,12-Lactam Moiety from Salvia scapiformis and Their Antiangiogenic Activity, PMID: 31668072
Monte Carlo Simulation Methodologies for β-Lactam/β-Lactamase Inhibitor Combinations: Effect on Probability of Target Attainment Assessments, PMID: 31423601
Targeting the Nonmevalonate Pathway in Burkholderia cenocepacia Increases Susceptibility to Certain β-Lactam Antibiotics, PMID: 29439968
Current challenges in antimicrobial chemotherapy: focus on ß-lactamase inhibition, PMID: 20394454
A new lactam alkaloid from Portulaca oleracea L. and its cytotoxity, PMID: 29022744
Metallo-beta-lactamases of Pseudomonas aeruginosa--a novel mechanism resistance to beta-lactam antibiotics, PMID: 18519228
Vitamin B12: chemical modifications, PMID: 23715409
Spiro-Lactams as Novel Antimicrobial Agents, PMID: 31702503
Recent developments in carbapenems, PMID: 11922861
Synthesis of Guaianolide Analogues with a Tunable α-Methylene-γ-lactam Electrophile and Correlating Bioactivity with Thiol Reactivity, PMID: 33201697
Enhancement of bactericidal activity against group B streptococci with reduced penicillin susceptibility by uptake of gentamicin into cells resulting from combination with β-lactam antibiotics, PMID: 28341517
Optimization of Bicyclic Lactam Derivatives as NMDA Receptor Antagonists, PMID: 28218498
Binding of TEM-1 beta-lactamase to beta-lactam antibiotics by frontal affinity chromatography, PMID: 28334649
GT32-B new 20-membered macrocyclic lactam antibiotic, PMID: 9099234
A novel and efficient chromophore reaction based on a lactam-fused aza-BODIPY for polyamine detection, PMID: 33070857
[Diagnostic evaluation of β-lactam antibiotic allergy], PMID: 24988157
Azithromycin compared with beta-lactam antibiotic treatment failures in pneumococcal infections of children, PMID: 15131461
Oligoamide, a new lactam from the leaves of Angylocalyx oligophyllus, PMID: 29882428
Limitations of beta-lactam therapy for infections caused by susceptible Gram-positive bacteria, PMID: 25124369
Production of beta-lactam antibiotics and its regulation, PMID: 1815263
Saccharothrix algeriensis NRRL B-24137, the first non-Streptomyces actinobacterium, produces holomycin after cystine feeding, PMID: 32642829
Discovery of ixabepilone, PMID: 19174552
Discovery of deoxylimonin δ-lactam derivative with favorable anti-inflammation and antinociception efficacy from chemical modified limonin/deoxylimonin analogs, PMID: 32371249
Potential effect of selective pressure with different β-lactam molecules on the emergence of reduced susceptibility to β-lactams in group B Streptococci, PMID: 30632638
Self-reported beta-lactam intolerance: not a class effect, dangerous to patients, and rarely allergy, PMID: 31067139
Novel Isoxazolidine and γ-Lactam Analogues of Homonucleosides, PMID: 31698778
Evolutionary ecology of beta-lactam gene clusters in animals, PMID: 28316142
Antibacterial chemotherapy. Part One. B-lactam antibiotics, PMID: 3328607
[B-lactam antibiotics: grouping according to their chemical structure and bacteriological properties], PMID: 3333440
Total Syntheses of Bulgecins A, B, and C and Their Bactericidal Potentiation of the β-Lactam Antibiotics, PMID: 29716193
Synergistic Interactions of Indole-2-Carboxamides and β-Lactam Antibiotics against Mycobacterium abscessus, PMID: 32041716
Design, Synthesis, and Biological Investigation of Epothilone B Analogues Featuring Lactone, Lactam, and Carbocyclic Macrocycles, Epoxide, Aziridine, and 1,1-Difluorocyclopropane and Other Fluorine Residues, PMID: 32065746
Design and Investigation of Optical Properties of N-(Rhodamine-B)-Lactam-Ethylenediamine (RhB-EDA) Fluorescent Probe, PMID: 29662009
[Guides for rational use of B-lactam antibiotics:resistance mechanism and clinical interpretation], PMID: 12872552
Lactam hybrid analogues of solonamide B and autoinducing peptides as potent S. aureus AgrC antagonists, PMID: 29738955
Treatment options for extended-spectrum beta-lactamase (ESBL) and AmpC-producing bacteria, PMID: 26891857
Optical microscopy reveals the dynamic nature of B. pseudomallei morphology during β-lactam antimicrobial susceptibility testing, PMID: 32677888
Intrapartum beta-lactam antibiotics for preventing group B streptococcal early-onset disease: can we abandon the concept of 'inadequate' intrapartum antibiotic prophylaxis?, PMID: 31762370
An update on adverse drug reactions related to β-lactam antibiotics, PMID: 29633867
Past and Present Perspectives on β-Lactamases, PMID: 30061284
β-Lactamases and β-Lactamase Inhibitors in the 21st Century, PMID: 30959050