Catalog No.
YHB40501
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Ala122
Predicted molecular weight
39.73 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O76070
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
PERSYN, Synoretin, Gamma-synuclein, Breast cancer-specific gene 1 protein, BCSG1, Persyn, PRSN, SR, SNCG
The effects of pigment epithelium-derived factor and associated peptides on the differentiation of retinal ganglion cells from human-induced pluripotent stem cells., PMID:40409357
Regulation of perisomatic synapses from cholecystokinin basket interneurons through NrCAM and Ankyrin B., PMID:40276719
Regulation of Perisomatic Synapses from Cholecystokinin Basket Interneurons through NrCAM and Ankyrin B., PMID:39574611
Brain Region-Specific Expression Levels of Synuclein Genes in an Acid Sphingomyelinase Knockout Mouse Model: Correlation with Depression-/Anxiety-Like Behavior and Locomotor Activity in the Absence of Genotypic Variation., PMID:39201372
Comparison of SNCG and NEFH Promoter-Driven Expression of Human SIRT1 Expression in a Mouse Model of Glaucoma., PMID:39177995
Retinal ganglion cell type-specific expression of synuclein family members revealed by scRNA-sequencing., PMID:38903914
Cyclic-NDGA Effectively Inhibits Human γ-Synuclein Fibrillation, Forms Nontoxic Off-Pathway Species, and Disintegrates Preformed Mature Fibrils., PMID:38637513
A prognostic model established using bile acid genes to predict the immunity and survival of patients with gastrointestinal cancer., PMID:38606991
Oral carcinogenesis and non-invasive biomarkers for the diagnosis of oral squamous cell carcinoma., PMID:38419239
The Herbal Combination Shu Gan Jie Yu Regulates the SNCG/ER-a/AKT-ERK Pathway in DMBA-Induced Breast Cancer and Breast Cancer Cell Lines Based on RNA-Seq and IPA Analysis., PMID:38369762
Substitution of Met-38 to Ile in γ-synuclein found in two patients with amyotrophic lateral sclerosis induces aggregation into amyloid., PMID:38170745
Emergence of the Synucleins., PMID:37626939
Differential Responses of Retinal Neurons and Glia Revealed via Proteomic Analysis on Primary and Secondary Retinal Ganglion Cell Degeneration., PMID:37569482
Upregulation of Parkinson's disease-associated protein alpha-synuclein suppresses tumorigenesis via interaction with mGluR5 and gamma-synuclein in liver cancer., PMID:37487948
Anatomical and molecular characterization of parvalbumin-cholecystokinin co-expressing inhibitory interneurons: implications for neuropsychiatric conditions., PMID:37443194
Senescence-related genes define prognosis, immune contexture, and pharmacological response in gastric cancer., PMID:37100457
Identification and validation of anoikis-associated gene SNCG as a prognostic biomarker in gastric cancer., PMID:36996495
Altered Expression of Genes Associated with Major Neurotransmitter Systems in the Reward-Related Brain Regions of Mice with Positive Fighting Experience., PMID:36362437
Effects of the Methylation Levels for the Breast Cancer Associated Genes BCSG1 and BRCA1 on Cellular Proliferation and Migration., PMID:36166741
Sncg, Mybpc1, and Parm1 Classify subpopulations of VIP-expressing interneurons in layers 2/3 of the somatosensory cortex., PMID:36030380
Multiomics characterization implicates PTK7 in ovarian cancer EMT and cell plasticity and offers strategies for therapeutic intervention., PMID:35977930
A new biomarker for the early diagnosis of gastric cancer: gastric juice- and serum-derived SNCG., PMID:35947016
A transcriptomic axis predicts state modulation of cortical interneurons., PMID:35794483
Selective Upregulation of SIRT1 Expression in Retinal Ganglion Cells by AAV-Mediated Gene Delivery Increases Neuronal Cell Survival and Alleviates Axon Demyelination Associated with Optic Neuritis., PMID:35740955
Gamma synuclein promotes cancer metastasis through the MKK3/6-p38MAPK cascade., PMID:35637967
Long Noncoding RNA Solute Carrier Family 25 Member 21 Antisense RNA 1 Inhibits Cell Malignant Behaviors and Enhances Radiosensitivity of Gastric Cancer Cells by Upregulating Synuclein Gamma Expression., PMID:35444105
Upregulation of Synuclein-γ and Snai1 Contributes to Poor Clinical Prognosis in Oral Squamous Cell Carcinoma Patients., PMID:35434126
Paracrine Interleukin 6 Induces Cerebral Remodeling at Early Stages After Unilateral Common Carotid Artery Occlusion in Mice., PMID:35155612
Noninvasive Detection of Esophageal Cancer by the Combination of mSEPT9 and SNCG., PMID:35089073
Single Cell Sequencing of Induced Pluripotent Stem Cell Derived Retinal Ganglion Cells (iPSC-RGC) Reveals Distinct Molecular Signatures and RGC Subtypes., PMID:34946963
A microRNA Cluster Controls Fat Cell Differentiation and Adipose Tissue Expansion By Regulating SNCG., PMID:34898027
The amyloid concentric β-barrel hypothesis: Models of synuclein oligomers, annular protofibrils, lipoproteins, and transmembrane channels., PMID:34570382
Gamma-synuclein is a novel prognostic marker that promotes tumor cell migration in biliary tract carcinoma., PMID:34245137
A Novel Ruthenium-Fluvastatin Complex Downregulates SNCG Expression to Modulate Breast Carcinoma Cell Proliferation and Apoptosis via Activating the PI3K/Akt/mTOR/VEGF/MMP9 Pathway., PMID:34221232
Proteomic analysis of human frontal and temporal cortex using iTRAQ-based 2D LC-MS/MS., PMID:33952343
Suppression of synuclein gamma inhibits the movability of endometrial carcinoma cells by PI3K/AKT/ERK signaling pathway., PMID:33788083
Study on the transcriptome for breast muscle of chickens and the function of key gene RAC2 on fibroblasts proliferation., PMID:33676413
Rescue of retinal ganglion cells in optic nerve injury using cell-selective AAV mediated delivery of SIRT1., PMID:33589779
Alternating sources of perisomatic inhibition during behavior., PMID:33529646
γ-Synuclein is Closely Involved in Autophagy that Protects Colon Cancer Cell from Endoplasmic Reticulum Stress., PMID:33463478
IGFBPs mediate IGF-1's functions in retinal lamination and photoreceptor development during pluripotent stem cell differentiation to retinal organoids., PMID:33442906
Silencing of BCSG1 with specific siRNA via nanocarriers for breast cancer treatment., PMID:33423781
Opportunistic screening and survival prediction of digestive cancers by the combination of blood mSEPT9 with protein markers., PMID:33403008
Dysregulated healing responses in diabetic wounds occur in the early stages postinjury., PMID:33350981
Inhibition of SNCG suppresses the proliferation of lung cancer cells induced by high glucose., PMID:33313952
[shRNA-Mediated Suppression of γ-Synuclein Leading to Downregulation of p38/ERK/JNK Phosphorylation and Cell Cycle Arrest in Endometrial Cancer Cells]., PMID:33276364
Assessment of serum synuclein-γ and squamous cell carcinoma antigen as diagnostic biomarkers in patients with oral squamous cell carcinoma and oral potentially malignant disorders., PMID:33064859
DLX6-AS1 accelerates cell proliferation through regulating miR-497-5p/SNCG pathway in prostate cancer., PMID:33035382
The down-regulation of SNCG inhibits the proliferation and invasiveness of human bladder cancer cell line 5637 and suppresses the expression of MMP-2/9., PMID:32782717
Genetics of synucleins in neurodegenerative diseases., PMID:32740728
For research use only. Not for human or drug use.
