Catalog No.
YHB34201
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Thr417-Tyr902
Predicted molecular weight
55.28 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O75891
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
10-FTHFDH, FDH, Aldehyde dehydrogenase family 1 member L1, Cytosolic 10-formyltetrahydrofolate dehydrogenase, ALDH1L1, FTHFD
DeSUMOylation of IGF2BP2 Promotes Neuronal Differentiation of OM-MSCs by Stabilizing SOX11 to Ameliorate Brain Injury After Intracerebral Hemorrhage., PMID:40485217
Interferon regulatory factor-1-expressing astrocytes are epigenetically controlled and exacerbate TBI-associated pathology in mice., PMID:40435213
Role of phospholipase Cη1 in lateral habenula astrocytes in depressive-like behavior in mice., PMID:40204881
SEC62-dependent ER-phagy contributes to apelin-13/APJ-induced monocyte-vascular endothelial cell adhesion in atherosclerosis pathogenesis., PMID:39930135
Aldh1l1-Cre/ERT2 Drives Flox-Mediated Recombination in Peripheral and CNS Infiltrating Immune Cells in Addition to Astrocytes During CNS Autoimmune Disease., PMID:39910805
Disrupted mitochondrial morphology and function exacerbate inflammation in elderly-onset ulcerative colitis., PMID:39794776
ALDH Enzymes and Hematological Diseases: A Scoping Review of Literature., PMID:39726306
Abnormal Astrocyte Heterogeneity in the Dentate Gyrus of Rats Prone to Audiogenic Seizures Can Be Corrected by the Nootropic Drug Piracetam., PMID:39711014
Single-cell transcriptomic and neuropathologic analysis reveals dysregulation of the integrated stress response in progressive supranuclear palsy., PMID:39648200
Efficient derivation of functional astrocytes from human induced pluripotent stem cells (hiPSCs)., PMID:39630626
Establishment and validation of diagnostic model in immunoglobulin A nephropathy based on weighted gene co-expression network analysis., PMID:39612439
Accumulation of Cerebrospinal Fluid, Ventricular Enlargement, and Cerebral Folate Metabolic Errors Unify a Diverse Group of Neuropsychiatric Conditions Affecting Adult Neocortical Functions., PMID:39337690
Integrated machine learning and bioinformatic analysis of mitochondrial-related signature in chronic rhinosinusitis with nasal polyps., PMID:39328210
Spatial-temporal representation of the astroglial markers in the developing human cortex., PMID:39153086
Proteomic evidence of depression-associated astrocytic dysfunction in the human male olfactory bulb., PMID:39128570
Astrocyte-derived lactate aggravates brain injury of ischemic stroke in mice by promoting the formation of protein lactylation., PMID:39113798
Evaluation of cerebrospinal fluid (CSF) and interstitial fluid (ISF) mouse proteomes for the validation and description of Alzheimer's disease biomarkers., PMID:39102902
Efficient Dlx2-mediated astrocyte-to-neuron conversion and inhibition of neuroinflammation by NeuroD1., PMID:39034481
Proteomic features of gray matter layers and superficial white matter of the rhesus monkey neocortex: comparison of prefrontal area 46 and occipital area 17., PMID:38943018
Structural identification and comprehension of human ALDH1L1-Gossypol complex., PMID:38917634
Immortalization and Characterization of GFAP-expressing Glial Cells from the Adult Mouse Hypothalamus, Cortex, and Brain Stem., PMID:38788830
Annotated dataset for training deep learning models to detect astrocytes in human brain tissue., PMID:38242926
FXTAS Neuropathology Includes Widespread Reactive Astrogliosis and White Matter Specific Astrocyte Degeneration., PMID:38069470
Single-cell transcriptomic and neuropathologic analysis reveals dysregulation of the integrated stress response in progressive supranuclear palsy., PMID:38014079
Astrocyte interferon-gamma signaling dampens inflammation during chronic central nervous system autoimmunity via PD-L1., PMID:37828609
Expression analysis of PPAR-related lncRNAs in breast cancer., PMID:37820438
Glial reactivity and T cell infiltration in frontotemporal lobar degeneration with tau pathology., PMID:37703311
Ethanol-induced transcriptional and translational changes in Aldh1l1-Egfp/Rpl10a cortical astrocyte cultures., PMID:37415614
The astrocytic Na+ -HCO3 - cotransporter, NBCe1, is dispensable for respiratory chemosensitivity., PMID:37384821
Hyaline protoplasmic astrocytopathy in epilepsy., PMID:37198977
Probing Protein 4'-Phosphopantetheinylation in Single Living Cells., PMID:37115508
Brain-specific glycosylation of protein tyrosine phosphatase receptor type Z (PTPRZ) marks a demyelination-associated astrocyte subtype., PMID:37005741
Administration of Kainic Acid Differentially Alters Astrocyte Markers and Transiently Enhanced Phospho-tau Level in Adult Rat Hippocampus., PMID:36805001
A Paternal Methylation Error in the Congenital Hydrocephalic Texas (H-Tx) Rat Is Partially Rescued with Natural Folate Supplements., PMID:36675153
Cerebral Folate Metabolism in Post-Mortem Alzheimer's Disease Tissues: A Small Cohort Study., PMID:36614107
Exploratory Metabolomics Underscores the Folate Enzyme ALDH1L1 as a Regulator of Glycine and Methylation Reactions., PMID:36500483
Monitoring regional astrocyte diversity by cell type-specific proteomic labeling in vivo., PMID:36401581
Abnormal downregulation of 10-formyltetrahydrofolate dehydrogenase promotes the progression of oral squamous cell carcinoma by activating PI3K/Akt/Rb pathway., PMID:36336972
Discovering a trans-omics biomarker signature that predisposes high risk diabetic patients to diabetic kidney disease., PMID:36323795
Neuroinflammation Plays a Critical Role in Cerebral Cavernous Malformation Disease., PMID:36285625
Proteomic analysis of skeletal muscle in Chinese hamsters with type 2 diabetes mellitus reveals that OPLAH downregulation affects insulin resistance and impaired glucose uptake., PMID:36195162
Glucocorticoid regulation of lactate release from spinal astrocytes contributes to the induction of spinal LTP of C-fiber-evoked field potentials and the development of mechanical allodynia., PMID:36108796
Astrocytic SARM1 promotes neuroinflammation and axonal demyelination in experimental autoimmune encephalomyelitis through inhibiting GDNF signaling., PMID:36055989
Distribution Patterns of Astrocyte Populations in the Human Cortex., PMID:35930103
Two novel CreERT2 transgenic mouse lines to study melanocytic cells in vivo., PMID:35920064
Cell type-specific biotin labeling in vivo resolves regional neuronal and astrocyte proteomic differences in mouse brain., PMID:35614064
Repressing PTBP1 fails to convert reactive astrocytes to dopaminergic neurons in a 6-hydroxydopamine mouse model of Parkinson's disease., PMID:35535997
Modulation of autoimmune diabetes by N-ethyl-N-nitrosourea- induced mutations in non-obese diabetic mice., PMID:35502705
Generation of Human iPSC-Derived Astrocytes with a mature star-shaped phenotype for CNS modeling., PMID:35488987
Partial Ablation of Astrocytes Exacerbates Cerebral Infiltration of Monocytes and Neuronal Loss After Brain Stab Injury in Mice., PMID:35437650
For research use only. Not for human or drug use.
