Catalog No.
YHB32201
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Lys134-Val334
Predicted molecular weight
25.31 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O75829
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
CNMD, Chondromodulin-I, ChM-I, MYETS1, Leukocyte cell-derived chemotaxin 1, LECT1, CH-SP, CHMI, Chondromodulin
MMP12-dependent myofibroblast formation contributes to nucleus pulposus fibrosis., PMID:40036084
Adenoid glioblastoma: Stromal hypovascularity and secretion of chondromodulin-I by tumor cells., PMID:39491322
Reassessment of marker genes in human induced pluripotent stem cells for enhanced quality control., PMID:39358374
A Narrative Review of the Roles of Chondromodulin-I (Cnmd) in Adult Cartilage Tissue., PMID:38892027
Cystine/glutamate antiporter xCT controls skeletal muscle glutathione redox, bioenergetics and differentiation., PMID:38815331
The integrated stress response promotes neural stem cell survival under conditions of mitochondrial dysfunction in neurodegeneration., PMID:38757355
PINK1 deficiency alters muscle stem cell fate decision and muscle regenerative capacity., PMID:38579709
Optic atrophy 1 mediates muscle differentiation by promoting a metabolic switch via the supercomplex assembly factor SCAF1., PMID:38414856
Digenic FLNA and UCHL1 variants resulting in a complex phenotype., PMID:38131667
Chondromodulin is necessary for cartilage callus distraction in mice., PMID:36795722
Identification of marker genes to monitor residual iPSCs in iPSC-derived products., PMID:36319564
The mitochondrial protein OPA1 regulates the quiescent state of adult muscle stem cells., PMID:35998642
Tenomodulin and Chondromodulin-1 Are Both Required to Maintain Biomechanical Function and Prevent Intervertebral Disc Degeneration., PMID:34486420
Robust detection of undifferentiated iPSC among differentiated cells., PMID:32581272
Loss of tenomodulin expression is a risk factor for age-related intervertebral disc degeneration., PMID:32083813
Chondromodulin-1 and vascular endothelial growth factor-A expression in esophageal squamous cell carcinoma: accelerator and brake theory for angiogenesis at the early stage of cancer progression., PMID:31595395
Chondromodulin-1 in health, osteoarthritis, cancer, and heart disease., PMID:31317206
Novel role of Snail 1 in promoting tumor neoangiogenesis., PMID:30975732
Chondromodulin‑I suppresses tumorigenesis of human osteosarcoma cells., PMID:28983591
Chondromodulin‑I expression and correlation with angiogenesis in human osteoarthritic cartilage., PMID:28627663
The endochondral bone protein CHM1 sustains an undifferentiated, invasive phenotype, promoting lung metastasis in Ewing sarcoma., PMID:28319320
Proteomic analysis of chondromodulin-I-induced differentiation of mesenchymal stem cells into chondrocytes., PMID:28263889
Whole-transcriptome sequencing in blood provides a diagnosis of spinal muscular atrophy with progressive myoclonic epilepsy., PMID:28251733
Chondromodulin-1 ameliorates osteoarthritis progression by inhibiting HIF-2α activity., PMID:27321194
A Prospectus of Tenomodulin., PMID:27383874
Human HLA-A*02:01/CHM1+ allo-restricted T cell receptor transgenic CD8+ T cells specifically inhibit Ewing sarcoma growth in vitro and in vivo., PMID:27281613
Transfection of chondromodulin I into human breast cancer cells and its effect on the inhibition of cancer cell growth., PMID:27035228
Chondromodulin-1 functions as a tumor suppressor in gastric adenocarcinoma., PMID:26165347
Chondrogenic differentiation of ChM-I gene transfected rat bone marrow-derived mesenchymal stem cells on 3-dimensional poly (L-lactic acid) scaffold for cartilage engineering., PMID:25319137
The influence of Chm-I knockout on ectopic cartilage regeneration and homeostasis maintenance., PMID:25251892
The N-terminal cleavage of chondromodulin-I in growth-plate cartilage at the hypertrophic and calcified zones during bone development., PMID:24710035
Consequences of chondrocyte hypertrophy on osteoarthritic cartilage: potential effect on angiogenesis., PMID:23973427
Chondromodulin-I derived from the inner meniscus prevents endothelial cell proliferation., PMID:23143879
LecT-Hepa, a glyco-marker derived from multiple lectins, as a predictor of liver fibrosis in chronic hepatitis C patients., PMID:22535703
Synthetic disulfide-bridged cyclic peptides mimic the anti-angiogenic actions of chondromodulin-I., PMID:22429838
[MYETS1 recombinant expression in prokaryotic cells and deletion analysis in multiple myeloma cell lines]., PMID:22349376
Maillard-conjugate based core-shell co-assemblies for nanoencapsulation of hydrophobic nutraceuticals in clear beverages., PMID:22193634
[Expression of chondromodulin-1 in the adult degenerative intervertebral disc]., PMID:22041680
Localization of chondromodulin-I at the feto-maternal interface and its inhibitory actions on trophoblast invasion in vitro., PMID:21849085
Increased macrophage infiltration and neovascularization in congenital bicuspid aortic valve stenosis., PMID:21481422
What makes the permanent articular cartilage permanent?, PMID:21391203
Chondromodulin 1 stabilizes the chondrocyte phenotype and inhibits endochondral ossification of porcine cartilage repair tissue., PMID:21391200
BRICHOS domain-containing leukocyte cell-derived chemotaxin 1-like cDNA from disk abalone Haliotis discus discus., PMID:20688173
Histone modifiers, YY1 and p300, regulate the expression of cartilage-specific gene, chondromodulin-I, in mesenchymal stem cells., PMID:20663886
A functional role of the glycosylated N-terminal domain of chondromodulin-I., PMID:20506028
Differential expression of Tenomodulin and Chondromodulin-1 at the insertion site of the tendon reflects a phenotypic transition of the resident cells., PMID:20334886
Impairment of VEGF-A-stimulated lamellipodial extensions and motility of vascular endothelial cells by chondromodulin-I, a cartilage-derived angiogenesis inhibitor., PMID:20026108
Expression of chondromodulin-1 in the temporomandibular joint condylar cartilage and disc., PMID:19903245
Transplanted chondrocytes inhibit endochondral ossification within cartilage repair tissue., PMID:19763370
Benzene metabolite hydroquinone up-regulates chondromodulin-I and inhibits tube formation in human bone marrow endothelial cells., PMID:19525446
For research use only. Not for human or drug use.
