Catalog No.
YHB27101
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ser66-Asn196
Predicted molecular weight
16.75 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O75629
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Cellular repressor of E1A-stimulated genes 1, Protein CREG1, CREG1, CREG
CREG1 alleviates bone loss in osteoporosis by enhancing the osteogenic differentiation of BMSCs through mitophagy., PMID:40378431
Hepatocyte cellular repressor of E1A-stimulated genes 1 protects against acetaminophen-induced liver injury by promoting autophagy., PMID:40133627
IL-33-Induced TREM2+ Macrophages Promote Pathological New Bone Formation Through CREG1-IGF2R Axis in Ankylosing Spondylitis., PMID:40091508
Aged mice overexpressing cellular repressor of E1A-stimulated genes 1 in adipose tissues exhibited increased liposarcoma incidence and shortened lifespan., PMID:39978253
CREG1 attenuates intervertebral disc degeneration by alleviating nucleus pulposus cell pyroptosis via the PINK1/Parkin-related mitophagy pathway., PMID:39746276
Identification of potential drug targets for diabetic polyneuropathy through Mendelian randomization analysis., PMID:39639394
Integrated multi-omic high-throughput strategies across-species identified potential key diagnostic, prognostic, and therapeutic targets for atherosclerosis under high glucose conditions., PMID:39223351
Association between genetically plasma proteins and osteonecrosis: a proteome-wide Mendelian randomization analysis., PMID:39119575
CREG1 attenuates doxorubicin-induced cardiotoxicity by inhibiting the ferroptosis of cardiomyocytes., PMID:39094399
Creg1 Regulates Erythroid Development via TGF-β/Smad2-Klf1 Axis in Zebrafish., PMID:38953462
CREG1 promotes bovine placental trophoblast cells exosome release by targeting IGF2R and participates in regulating organoid differentiation via exosomes transport., PMID:38917918
CREG1 deficiency impaired myoblast differentiation and skeletal muscle regeneration., PMID:38272853
Extracellular vesicle-derived TP53BP1, CD34, and PBX1 from human peripheral blood serve as potential biomarkers for the assessment and prediction of vascular aging., PMID:38173016
Transcriptome-wide map of N6-methyladenosine (m6A) profiling in coronary artery disease (CAD) with clopidogrel resistance., PMID:38098098
The CREG1-FBXO27-LAMP2 axis alleviates diabetic cardiomyopathy by promoting autophagy in cardiomyocytes., PMID:37658156
The role of CREG1 in megakaryocyte maturation and thrombocytopoiesis., PMID:37496998
PABPN1 promotes clear cell renal cell carcinoma progression by suppressing the alternative polyadenylation of SGPL1 and CREG1., PMID:37452741
A Multiomic Analysis of Chicken Serum Revealed the Modulation of Host Factors Due to Campylobacter jejuni Colonization and In-Water Supplementation of Eugenol Nanoemulsion., PMID:36830346
CREG1 stimulates AMPK phosphorylation and glucose uptake in skeletal muscle cells., PMID:36528955
CREG ameliorates embryonic stem cell differentiation into smooth muscle cells by modulation of TGF-β expression., PMID:35349881
Hepatocyte-specific deletion of cellular repressor of E1A-stimulated genes 1 exacerbates alcohol-induced liver injury by activating stress kinases., PMID:35280676
Flow cytometry-based study of model marine microalgal consortia revealed an ecological advantage of siderophore utilization by the dinoflagellate Amphidinium carterae., PMID:35024100
CREG1 improves diet-induced obesity via uncoupling protein 1-dependent manner in mice., PMID:35007381
CREG1 administration stimulates BAT thermogenesis and improves diet-induced obesity in mice., PMID:34647124
GATA3 improves the protective effects of bone marrow-derived mesenchymal stem cells against ischemic stroke induced injury by regulating autophagy through CREG., PMID:34500038
CREG1 promotes lysosomal biogenesis and function., PMID:33966596
CREG1 improves the capacity of the skeletal muscle response to exercise endurance via modulation of mitophagy., PMID:33726618
Complex Response of the Chlorarachniophyte Bigelowiella natans to Iron Availability., PMID:33563784
Effects of CREG1 on Age-Associated Metabolic Phenotypes and Renal Senescence in Mice., PMID:33525404
CREG improves cardiac function by regulating cardiomyocytes' autophagy in diabetic myocardial infarction rats., PMID:33215442
The secreted inhibitor of invasive cell growth CREG1 is negatively regulated by cathepsin proteases., PMID:32385587
Recombinant Cellular Repressor of E1A-Stimulated Genes Protects against Renal Fibrosis in Dahl Salt-Sensitive Rats., PMID:32320986
DNA hypermethylation: A novel mechanism of CREG gene suppression and atherosclerogenic endothelial dysfunction., PMID:32067910
Lyophilized Maqui (Aristotelia chilensis) Berry Induces Browning in the Subcutaneous White Adipose Tissue and Ameliorates the Insulin Resistance in High Fat Diet-Induced Obese Mice., PMID:31480627
Epoxyeicosatrienoic intervention improves NAFLD in leptin receptor deficient mice by an increase in PGC1α-HO-1-PGC1α-mitochondrial signaling., PMID:31039348
CREG1 stimulates brown adipocyte formation and ameliorates diet-induced obesity in mice., PMID:30917000
The Structure and Biological Function of CREG., PMID:30416997
CREG1 promotes uncoupling protein 1 expression and brown adipogenesis in vitro., PMID:30295852
Antiapoptotic role of the cellular repressor of E1A-stimulated genes (CREG) in retinal photoreceptor cells in a rat model of light-induced retinal injury., PMID:29864918
Hypoxia-Inducible Factor-1α (HIF-1α) Expression on Endothelial Cells in Juvenile Nasopharyngeal Angiofibroma: A Review of 70 cases and Tissue Microarray Analysis., PMID:29717655
CREG1 heterozygous mice are susceptible to high fat diet-induced obesity and insulin resistance., PMID:28459882
Cellular Repressor of E1A-Stimulated Genes Is a Critical Determinant of Vascular Remodeling in Response to Angiotensin II., PMID:28062494
Cellular Repressor of E1A-stimulated Genes, A New Potential Therapeutic Target for Atherosclerosis., PMID:27784214
CREG1 Interacts with Sec8 to Promote Cardiomyogenic Differentiation and Cell-Cell Adhesion., PMID:27334848
Up-Regulation of CREG Expression by the Transcription Factor GATA1 Inhibits High Glucose- and High Palmitate-Induced Apoptosis in Human Umbilical Vein Endothelial Cells., PMID:27139506
Glycoproteomic Approach Identifies KRAS as a Positive Regulator of CREG1 in Non-small Cell Lung Cancer Cells., PMID:26722374
Common prefrontal cortical gene expression profiles between adolescent SHR/NCrl and WKY/NCrl rats which showed inattention behavior., PMID:26048425
CREG1 ameliorates myocardial fibrosis associated with autophagy activation and Rab7 expression., PMID:25774384
Bovine milk proteome in the first 9 days: protein interactions in maturation of the immune and digestive system of the newborn., PMID:25693162
Cellular repressor of E1A-stimulated gene overexpression in bone mesenchymal stem cells protects against rat myocardial infarction., PMID:25679992
For research use only. Not for human or drug use.
