Catalog No.
YHB26901
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
His493-Lys678
Predicted molecular weight
22.83 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O75626
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
BLIMP-1, PRDI-BF1, PRDI-binding factor 1, BLIMP1, Positive regulatory domain I-binding factor 1, Beta-interferon gene positive regulatory domain I-binding factor, PR domain-containing protein 1, PR domain zinc finger protein 1, PRDM1
Targeting the interaction between long noncoding RNA XR_001779380 and Prdm1 to enhance IFN-γ immunity in murine neonatal intestinal epithelial cells., PMID:40497734
N-glycosylated LTβR increases the Th17/Treg cell ratio in liver cancer by blocking RORC ubiquitination and FOXP3 transcription., PMID:40436857
Blocking plasma cell fate enhances antigen-specific presentation by B cells to boost anti-tumor immunity., PMID:40360528
MiR- 223 alleviates the heat-stress-induced inhibition of cell proliferation by targeting PRDM1., PMID:40355855
[Relapse-related candidate genes and their clinicopathological connections of diffuse large B cell lymphoma]., PMID:40159024
Decoding plasma cell maturation dynamics with BCMA., PMID:40134424
Glucose modulates IRF6 transcription factor dimerization to enable epidermal differentiation., PMID:40120584
NSD2-epigenomic reprogramming and maintenance of plasma cell phenotype in t(4;14) myeloma., PMID:40116454
Gut IgA-antibody secreting cells segregate into four Blimp1+ subsets based on differential expression of IgA and Ki-67 and are retained following prolonged αCD20 B cell depletion in mice., PMID:40073093
BLIMP-1-dependent differentiation of T follicular helper cells into Foxp3+ T regulatory type 1 cells., PMID:40066448
mRNA splicing variants of the transcription factor Blimp1 differentially regulate germline genes in echinoderms., PMID:40024498
BMSC-derived exosomes improve rheumatoid arthritis by regulating Th17 cell differentiation through targeting PRDM1., PMID:40022525
Ginsenoside Rg1 alleviated experimental colitis in obesity mice by regulating memory follicular T cells via Bcl-6/Blimp-1 pathway., PMID:40021065
Maternal PRDM10 activates essential genes for oocyte-to-embryo transition., PMID:39994175
Distinct plasmablast developmental intermediates produce graded expression of IgM secretory transcripts., PMID:39923238
Regulation of NK cell development, maturation, and antitumor responses by the nuclear receptor NR2F6., PMID:39920136
PR/SET domain 1 targeting glutathione peroxidase 4 regulates chronic hepatitis B liver fibrosis through ferroptosis., PMID:39917009
Blimp-1 orchestrates macrophage polarization and metabolic homeostasis via purine biosynthesis in sepsis., PMID:39915460
Autoimmunity promotes chronic lymphocytic leukemia progression in an indolent disease model., PMID:39900937
The zinc-finger transcription factor Blimp1/Prdm1 is required for uterine remodelling and repair in the mouse., PMID:39890816
RIF1 integrates DNA repair and transcriptional requirements during the establishment of humoral immune responses., PMID:39824820
PRDM1 Is a Key Regulator of the NKT-cell Central Memory Program and Effector Function., PMID:39820712
DDX50 cooperates with STAU1 to effect stabilization of pro-differentiation RNAs., PMID:39764852
Activated PRDM1-CREBBP contributes to preeclampsia by regulating apoptosis and invasion of the human trophoblast cells., PMID:39759022
TP53 Mutation Is the Only Robust Mutational Biomarker for Outcome Found in a Consecutive Clinical Cohort of Real-Word Patients With Primary Large B-Cell Lymphoma., PMID:39691999
A comprehensive investigation of PRMT5 in the prognosis and ion channel features of lung cancer., PMID:39678513
Genetic disruption of Blimp-1 drastically augments the antitumor efficacy of BCMA-targeting CAR T cells., PMID:39642314
It's the little things in life: Lymph node microniches drive TH2 formation in allergic asthma., PMID:39642245
Assessing human B cell responses to influenza virus vaccines and adjuvants in a PBMC-derived in vitro culture system., PMID:39616951
Interleukin-2-secreting T helper cells promote extra-follicular B cell maturation via intrinsic regulation of a B cell mTOR-AKT-Blimp-1 axis., PMID:39612915
Mechanism of PD-1/PD-L1 in Regulating cTfr/cTfh Balance in Patients with Rheumatoid Arthritis., PMID:39586747
Functional Targets for Epstein-Barr Virus BART MicroRNAs in B Cell Lymphomas., PMID:39456631
Construction of mitochondrial quality regulation genes-related prognostic model based on bulk-RNA-seq analysis in multiple myeloma., PMID:39446019
PRDM1 promotes nucleus pulposus cell pyroptosis leading to intervertebral disc degeneration via activating CASP1 transcription., PMID:39432156
D1-like dopamine receptors promote B-cell differentiation in systemic lupus erythematosus., PMID:39420360
Spatial microniches of IL-2 combine with IL-10 to drive lung migratory TH2 cells in response to inhaled allergen., PMID:39394532
Absolute quantification of BACH1 and BACH2 transcription factors in B and plasma cells reveals their dynamic changes and unique roles., PMID:39323025
Dissecting the metabolic signaling pathways by which microbial molecules drive the differentiation of regulatory B cells., PMID:39265892
Exosomal lncRNA TUG1 derived from BMSC ameliorate collagen-induced arthritis via BLIMP1-mediated Th17/Treg balance., PMID:39241514
Adaptive Evolution and Functional Differentiation of Testis-Expressed Genes in Theria., PMID:39199849
An autoimmune transcriptional circuit drives FOXP3+ regulatory T cell dysfunction., PMID:39196959
Blunting specific T-dependent antibody responses with engineered "decoy" B cells., PMID:39192583
IL-27/Blimp-1 axis regulates the differentiation and function of Tim-3+ Tregs during early pregnancy., PMID:39171524
Prdm1 positively regulates liver Group 1 ILCs cancer immune surveillance and preserves functional heterogeneity., PMID:39133873
Blockade of LAG-3 and PD-1 leads to co-expression of cytotoxic and exhaustion gene modules in CD8+ T cells to promote antitumor immunity., PMID:39121849
PTIP epigenetically regulates DNA damage-induced cell cycle arrest by upregulating PRDM1., PMID:39097652
Chronic viral infection alters PD-1 locus subnuclear localization in cytotoxic CD8+ T cells., PMID:39083377
PRDM1 promotes the ferroptosis and immune escape of thyroid cancer by regulating USP15-mediated SELENBP1 deubiquitination., PMID:39014173
PHLDA1-PRDM1 mediates the effect of lentiviral vectors on fate-determination of human retinal progenitor cells., PMID:39012348
Epigenetic recording of stimulation history reveals BLIMP1-BACH2 balance in determining memory B cell fate upon recall challenge., PMID:38969872
For research use only. Not for human or drug use.
