Catalog No.
YHB23801
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Asp142-Arg441
Predicted molecular weight
36.98 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O75530
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Polycomb protein EED, WAIT-1, EED, hEED, WD protein associating with integrin cytoplasmic tails 1, Embryonic ectoderm development protein
Coordinated regulation of chromatin modifiers reflects organised epigenetic programming in mouse oocytes., PMID:40186324
Inhibition of EED-mediated histone methylation alleviates neuroinflammation by suppressing WNT-mediated dendritic cell migration., PMID:40169990
An updated patent review of EZH2 inhibitors (2024-present)., PMID:40116819
Polycomb repressive complex 2 (PRC2) pathway's role in cancer cell plasticity and drug resistance., PMID:40048009
Further exploration of the quantitative distance-energy and contact number-energy relationships for predicting the binding affinity of protein-ligand complexes., PMID:40017034
A Bioactive Benzimidazole-Cyclometalated Iridium(III) Complex as an Epigenetic Regulator through Effectively Interrupting the EED-EZH2 Interaction., PMID:39967436
Mettl3/Eed/Ythdc1 regulatory axis controls endometrial receptivity and function., PMID:39934221
Bisphenol B restrains rat leydig cell function via H3K27me3/H3K9me3 histone modifications., PMID:39919587
Enhanced solid-liquid synergistic microextraction of nine bisphenols in serum using polyaniline functionalized metal-organic framework nanocomposites/methyl tert-butyl ether., PMID:39890622
Impact of Ligand-Induced Oligomer Dissociation on Enzyme Diffusion, Directly Observed at the Single-Molecule Level., PMID:39879145
Estimating total-tract digestibility of nutrients and their contribution to digestible energy supplies in equine diets., PMID:39862999
Pathophysiological Features of Remodeling in Vascular Diseases: Impact of Inhibitor of DNA-Binding/Differentiation-3 and Estrogenic Endocrine Disruptors., PMID:39846697
A conserved switch to less catalytically active Polycomb repressive complexes in non-dividing cells., PMID:39799569
Triple Combination of MEK, BET, and CDK Inhibitors Significantly Reduces Human Malignant Peripheral Nerve Sheath Tumors in Mouse Models., PMID:39786423
Structural basis for the inhibition of PRC2 by active transcription histone posttranslational modifications., PMID:39774834
Single cell transcriptomics of the cerebral cortex of mice lacking the PRC2 gene eed., PMID:39719612
Daily Complementary Feeding With Eggs Improves Fibroblast Growth Factor 21 in Infants., PMID:39648796
Associations of poor water, sanitation, and hygiene and parasite burden with markers of environmental enteric dysfunction in preschool-age children infected with Schistosoma mansoni in Uganda., PMID:39618064
A polycomb group protein EED epigenetically regulates responses in lipopolysaccharide tolerized macrophages., PMID:39614386
Genomic Alterations in DNA Mismatch Repair Genes Across Different Cancer Types., PMID:39576951
Folic acid mitigates the developmental and neurotoxic effects of bisphenol A in zebrafish by inhibiting the oxidative stress/JNK signaling pathway., PMID:39566264
Markers of Environmental Enteric Dysfunction are Associated with Poor Growth and Developmental Outcomes among Young Children in Lusaka, Zambia., PMID:39551093
Hypermethylation of CDKN2A CpG island drives resistance to PRC2 inhibitors in SWI/SNF loss-of-function tumors., PMID:39500892
An EED/PRC2-H19 Loop Regulates Cerebellar Development., PMID:39498824
Prevalence of and factors associated with pre-diabetes among adolescents in Eastern Sudan: a community-based cross-sectional study., PMID:39384233
Phase I/II study of BMS-986156 with ipilimumab or nivolumab with or without stereotactic ablative radiotherapy in patients with advanced solid malignancies., PMID:39384194
Eed-dependent histone modification orchestrates the iNKT cell developmental program alleviating liver injury., PMID:39372408
The Impact of Milk on Gut Permeability, Fecal 16S rRNA Gene Microbiota Profiling, and Fecal Metabolomics in Children with Moderate Malnutrition in Sierra Leone: A Double-Blind, Randomized Controlled Trial., PMID:39307188
Activation of automethylated PRC2 by dimerization on chromatin., PMID:39303719
Biomarker relationships with small bowel histopathology among malnourished children with environmental enteric dysfunction in a multicountry cohort study., PMID:39300665
Effects of Vitamin D-3 Supplementation During Pregnancy and Lactation on Maternal and Infant Biomarkers of Environmental Enteric Dysfunction, Systemic Inflammation, and Growth: A Secondary Analysis of a Randomized Controlled Trial., PMID:39278411
MAT2A is essential for zygotic genome activation by maintaining of histone methylation in porcine embryos., PMID:39276507
A repressive H3K36me2 reader mediates Polycomb silencing., PMID:39179589
Reconstruction of single-cell lineage trajectories and identification of diversity in fates during the epithelial-to-mesenchymal transition., PMID:39093947
Polycomb repressive complex 2 is critical for mouse cortical glutamatergic neuron development., PMID:38960704
Protection from environmental enteric dysfunction and growth improvement in malnourished newborns by amplification of secretory IgA., PMID:38959887
EZH2-associated tumor malignancy: A prominent target for cancer treatment., PMID:38881299
Biallelic loss-of-function variants of EZH1 cause a novel developmental disorder with central precocious puberty., PMID:38814056
Fetal growth delay caused by loss of non-canonical imprinting is resolved late in pregnancy and culminates in offspring overgrowth., PMID:38813868
Genomic context- and H2AK119 ubiquitination-dependent inheritance of human Polycomb silencing., PMID:38718120
Chemotherapy-elicited extracellular vesicle CXCL1 from dying cells promotes triple-negative breast cancer metastasis by activating TAM/PD-L1 signaling., PMID:38654356
BRG1 programs PRC2-complex repression and controls oligodendrocyte differentiation and remyelination., PMID:38652118
Baseline perihematomal edema, C-reactive protein, and 30-day mortality are not associated in intracerebral hemorrhage., PMID:38645743
Targeting EED as a key PRC2 complex mediator toward novel epigenetic therapeutics., PMID:38642703
Discovery and Characterization of a Novel Cereblon-Recruiting PRC1 Bridged PROTAC Degrader., PMID:38607318
Isothiocyanates Potentiate Tazemetostat-Induced Apoptosis by Modulating the Expression of Apoptotic Genes, Members of Polycomb Repressive Complex 2, and Levels of Tri-Methylating Lysine 27 at Histone 3 in Human Malignant Melanoma Cells., PMID:38473991
Quiescence enables unrestricted cell fate in naive embryonic stem cells., PMID:38409226
Structural basis for the inhibition of PRC2 by active transcription histone posttranslational modifications., PMID:38370759
Environmental chemical TCPOBOP exposure alters milk liposomes and offspring growth trajectories in mice., PMID:38340598
For research use only. Not for human or drug use.
