Catalog No.
YHB21001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Lys167
Predicted molecular weight
21.66 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O75449
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Katanin p60 ATPase-containing subunit A1, p60 katanin, KATNA1, Katanin p60 subunit A1
The interaction between KATNA1 and CRMP3 modulates microtubule dynamics and neurite outgrowth., PMID:39938451
SUMOylation of nuclear receptor Nor1/NR4A3 coordinates microtubule cytoskeletal dynamics and stability in neuronal cells., PMID:38997783
The katanin A-subunits KATNA1 and KATNAL1 act co-operatively in mammalian meiosis and spermiogenesis to achieve male fertility., PMID:37882691
The Scaffold Protein KATNIP Enhances CILK1 Control of Primary Cilia., PMID:37665596
A potential posttranscriptional regulator for p60-katanin: miR-124-3p., PMID:37439368
Comprehensive analysis of the human ESCRT-III-MIT domain interactome reveals new cofactors for cytokinetic abscission., PMID:36107470
SUMOylation of microtubule-cleaving enzyme KATNA1 promotes microtubule severing and neurite outgrowth., PMID:35868557
Effects of DISC1 on Alzheimer's disease cell models assessed by iTRAQ proteomics analysis., PMID:34981809
Wdr47, Camsaps, and Katanin cooperate to generate ciliary central microtubules., PMID:34608154
Transcriptome Analysis of Juvenile Tilapia (Oreochromis niloticus) Blood, Fed With Different Concentrations of Resveratrol., PMID:33362577
Katanin P60 and P80 in papillary thyroid carcinoma patients: Indicators for exacerbated tumor features and worse disease-free survival., PMID:33274499
Katanin P60: a potential biomarker for lymph node metastasis and prognosis for non-small cell lung cancer., PMID:32631334
Cardiomyocyte Proteome Remodeling due to Isoproterenol-Induced Cardiac Hypertrophy during the Compensated Phase., PMID:32506788
p53 regulates katanin-p60 promoter in HCT 116 cells., PMID:31715301
The Microtubule Severing Protein Katanin Regulates Proliferation of Neuronal Progenitors in Embryonic and Adult Neurogenesis., PMID:31685876
Microtubule‑severing protein Katanin p60 ATPase‑containing subunit A‑like 1 is involved in pole‑based spindle organization during mouse oocyte meiosis., PMID:31485656
Crystal Structure of a Heterotetrameric Katanin p60:p80 Complex., PMID:31353241
Elk1 affects katanin and spastin proteins via differential transcriptional and post-transcriptional regulations., PMID:30789974
KATNAL1 is a more active and stable isoform of katanin, and is expressed dominantly in neurons., PMID:30448058
Creation and testing of a new, local microtubule-disruption tool based on the microtubule-severing enzyme, katanin p60., PMID:30176123
Clinical relevance of cytoskeleton associated proteins for ovarian cancer., PMID:30094535
Structural basis of katanin p60:p80 complex formation., PMID:29097679
Mutations in the Katnb1 gene cause left-right asymmetry and heart defects., PMID:28791777
Microtubule minus-end regulation at spindle poles by an ASPM-katanin complex., PMID:28436967
A missense mutation in Katnal1 underlies behavioural, neurological and ciliary anomalies., PMID:28373692
Proteomic Analysis of the Mammalian Katanin Family of Microtubule-severing Enzymes Defines Katanin p80 subunit B-like 1 (KATNBL1) as a Regulator of Mammalian Katanin Microtubule-severing., PMID:26929214
Differential regulation of microtubule severing by APC underlies distinct patterns of projection neuron and interneuron migration., PMID:25535916
Mutations in KATNB1 cause complex cerebral malformations by disrupting asymmetrically dividing neural progenitors., PMID:25521378
USP47 and C terminus of Hsp70-interacting protein (CHIP) antagonistically regulate katanin-p60-mediated axonal growth., PMID:23904609
Katanin-p80 gene promoter characterization and regulation via Elk1., PMID:23894477
KATNAL1 regulation of sertoli cell microtubule dynamics is essential for spermiogenesis and male fertility., PMID:22654668
Aberrant expression of katanin p60 in prostate cancer bone metastasis., PMID:21681775
Regulation of katanin-P60 levels by LECT2 adjusts microtubular morphology., PMID:20463617
For research use only. Not for human or drug use.
