Catalog No.
YHB04301
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gly64-Val334
Predicted molecular weight
32.21 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O60911
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
CTSL2, Cathepsin U, Cathepsin L2, Cathepsin V, CTSU, CATL2, CTSV
Identification and validation of a lenvatinib resistance-related prognostic signature in HCC, in which PFKFB4 contributes to tumor progression and lenvatinib resistance., PMID:40269756
Ugonin inhibits chondrosarcoma metastasis through suppressing cathepsin V via promoting miR-4799-5p expression., PMID:39897041
Profiling of Potential Anti-Diabetic Active Compounds in White Tea: An Integrated Study of Polyphenol-Targeted Metabolomics, Network Pharmacology, and Computer Simulation., PMID:39517138
Genomic analysis reveals molecular characterization of CD30+ and CD30- extranodal natural killer/T-cell lymphomas (ENKTLs)., PMID:39187207
Cathepsin V is a useful prognostic factor for colorectal cancer., PMID:39153237
Proteomics profiling and association with cardiorenal complications in type 2 diabetes subtypes in Asian population., PMID:39059739
Cathepsin V drives lung cancer progression by shaping the immunosuppressive environment and adhesion molecules cleavage., PMID:38078882
Cathepsin V is correlated with the prognosis and tumor microenvironment in liver cancer., PMID:38051285
Cathepsin V regulates cell cycle progression and histone stability in the nucleus of breast cancer cells., PMID:38026973
A Novel Defined Pyroptosis-Related Gene Signature for Predicting the Prognosis of Endometrial Cancer., PMID:36601599
CTSV (cathepsin V) promotes bladder cancer progression by increasing NF-κB activity., PMID:35443863
Identification of Key Genes Associated with Progression and Prognosis of Bladder Cancer through Integrated Bioinformatics Analysis., PMID:34885040
Cystatin M/E Variant Causes Autosomal Dominant Keratosis Follicularis Spinulosa Decalvans by Dysregulating Cathepsins L and V., PMID:34322157
Aminopeptidase Expression in Multiple Myeloma Associates with Disease Progression and Sensitivity to Melflufen., PMID:33810334
Cathepsin V suppresses GATA3 protein expression in luminal A breast cancer., PMID:33298139
The abnormal accumulation of heparan sulfate in patients with mucopolysaccharidosis prevents the elastolytic activity of cathepsin V., PMID:33278943
Cathepsin V Mediates the Tazarotene-induced Gene 1-induced Reduction in Invasion in Colorectal Cancer Cells., PMID:32918681
HMGB1 mediates homocysteine-induced endothelial cells pyroptosis via cathepsin V-dependent pathway., PMID:32912629
Significance of nuclear cathepsin V in normal thyroid epithelial and carcinoma cells., PMID:32910988
Extracellular Matrix Injury of Kidney Allografts in Antibody-Mediated Rejection: A Proteomics Study., PMID:32900843
OSucs: An Online Prognostic Biomarker Analysis Tool for Uterine Carcinosarcoma., PMID:32899312
IL6R is a target of miR-197 in human keratinocytes., PMID:32780449
Praeruptorin B Mitigates the Metastatic Ability of Human Renal Carcinoma Cells through Targeting CTSC and CTSV Expression., PMID:32331211
Expression of elastolytic cathepsins in human skin and their involvement in age-dependent elastin degradation., PMID:32007579
HCE-T cell line lacks cornea-specific differentiation markers compared to primary limbal epithelial cells and differentiated corneal epithelium., PMID:31927639
Characterization of cathepsin S exosites that govern its elastolytic activity., PMID:31860022
Angiotensin II-Induced vascular remodeling and hypertension involves cathepsin L/V- MEK/ERK mediated mechanism., PMID:31668507
A Zingerone Analog, Acetyl Zingerone, Bolsters Matrisome Synthesis, Inhibits Matrix Metallopeptidases, and Represses IL-17A Target Gene Expression., PMID:31465741
Prognostic significance of cathepsin V (CTSV/CTSL2) in breast ductal carcinoma in situ., PMID:31444238
A novel preventive mechanism of gentamicin-induced nephrotoxicity by atorvastatin., PMID:31256419
[Cathepsin B Affects the Activation of Nucleotide-binding Domain and Leucine-rich-repeat-containing Family and Pyrin Domain-containing 3 Inflammasome via Transient Receptor Potential Mucolipin-1]., PMID:31060676
Possible Association between Cathepsin V and the Development of Placenta Accreta Spectrum Disorders., PMID:30759440
Expression of retinoic acid signaling components ADH7 and ALDH1A1 is reduced in aniridia limbal epithelial cells and a siRNA primary cell based aniridia model., PMID:30292490
Copy number profiling of Oncotype DX genes reveals association with survival of breast cancer patients., PMID:30225582
Melanosome degradation in epidermal keratinocytes related to lysosomal protease cathepsin V., PMID:29654760
Degraded melanocores are incompetent to protect epidermal keratinocytes against UV damage., PMID:29623762
Cell and genetic predictors of human blastocyst hatching success in assisted reproduction., PMID:28929987
Multiplex Cathepsin Zymography to Detect Amounts of Active Cathepsins K, L, S, and V., PMID:28608217
Exogenous cathepsin V protein protects human cardiomyocytes HCM from angiotensin Ⅱ-Induced hypertrophy., PMID:28522343
Expression of cathepsins V and S in thymic epithelial tumors., PMID:27771373
New Marker Genes for Real-Time PCR-based Detection of Circulating Tumour Cells from Blood of Breast Cancer Patients., PMID:27272851
Neuropeptidomics Mass Spectrometry Reveals Signaling Networks Generated by Distinct Protease Pathways in Human Systems., PMID:26483184
Endostatin and cathepsin-V in bronchoalveolar lavage fluid of patients with pulmonary sarcoidosis., PMID:25252891
Elastin degradation by cathepsin V requires two exosites., PMID:24121514
Plasma levels of cathepsins L, K, and V and risks of abdominal aortic aneurysms: a randomized population-based study., PMID:23958260
MAIN software for density averaging, model building, structure refinement and validation., PMID:23897458
Differential expression of cathepsins K, S and V between young and aged Caucasian women skin epidermis., PMID:23871919
CTSL2 is a pro-apoptotic target of E2F1 and a modulator of histone deacetylase inhibitor and DNA damage-induced apoptosis., PMID:23542171
Decreased cathepsin V expression due to Fli1 deficiency contributes to the development of dermal fibrosis and proliferative vasculopathy in systemic sclerosis., PMID:23287360
Hydrolytic enzymes of the interfollicular epidermis differ in expression and correlate with the phenotypic difference observed between light and dark skin., PMID:23088390
For research use only. Not for human or drug use.
