Catalog No.
YHA99801
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Leu199
Predicted molecular weight
25.65 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O60760
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
GST class-sigma, Prostaglandin-H2 D-isomerase, PTGDS2, Glutathione-dependent PGD synthase, Hematopoietic prostaglandin D synthase, PGDS, HPGDS, Glutathione-requiring prostaglandin D synthase, GSTS, H-PGDS, Glutathione S-transferase
Metabolome and transcriptome analyses reveal the mechanism underlying the differences in skin development between the two duck breeds during embryonic stage., PMID:40499236
Identifying Key Plasma Proteins in the Onset of Parkinson's Disease: Proteome-Wide Mendelian Randomization and Single-Cell RNA Sequencing Analysis., PMID:40380075
Periodic dietary restriction of animal products induces metabolic reprogramming in humans with effects on cardiometabolic health., PMID:40225784
Diet-Induced Obesity Alters Granulosa Cell Transcriptome and Ovarian Immune Environment in Mice., PMID:40141675
Finding Potential Drug Targets for Pre-Eclampsia Using Mendelian Randomisation and Colocalisation Analysis., PMID:40028697
Large-scale proteomic analyses of incident Parkinson's disease reveal new pathophysiological insights and potential biomarkers., PMID:39979637
Plasma Proteomic Signatures of Physical Activity Provide Insights into Biological Impacts of Physical Activity and its Protective Role Against Dementia., PMID:39867359
Single-cell transcriptomics reveals the heterogeneity and function of mast cells in human ccRCC., PMID:39840068
Association of Arachidonic Acid Metabolism Related Genes With Endometrial Immune Microenvironment and Oxidative Stress in Coupes With Recurrent Implantation Failure., PMID:39803797
Weighted gene co-expression network analysis reveals key stromal prognostic markers in pancreatic cancer., PMID:39738404
[Molecular mechanism of high-altitude hypoxia-induced lipid metabolism disorder in mouse spleen tissue]., PMID:39523103
Urinary biomarkers for active Lupus Nephritis that have survived independent validation across cohorts., PMID:39370040
Proteogenomic signature of risk of Alzheimer's disease and related dementia risk in individuals with a history of major depression disorder., PMID:39314945
Discovering potential asthma therapeutics targeting hematopoietic prostaglandin D2 synthase: An integrated computational approach., PMID:39307263
Single-nucleus RNA sequencing reveals cell types, genes, and regulatory factors influencing melanogenesis in the breast muscle of Xuefeng black-bone chicken., PMID:39278114
Identification of novel biomarkers and potential molecular targets for uterine cancer using network-based approach., PMID:39029376
In Silico Design, Synthesis, and Evaluation of PROTAC Against Hematopoietic Prostaglandin D Synthase., PMID:38987477
Single-cell data revealed exhaustion of characteristic NK cell subpopulations and T cell subpopulations in hepatocellular carcinoma., PMID:38604154
Hematopoietic Prostaglandin D Synthase Is Increased in Mast Cells and Pericytes in Autopsy Myocardial Specimens from Patients with Duchenne Muscular Dystrophy., PMID:38339125
Prostaglandin D2 is involved in the regulation of inflammatory response in Staphylococcus aureus-infected mice macrophages., PMID:38295545
Mendelian randomization identifies circulating proteins as biomarkers for age at menarche and age at natural menopause., PMID:38184718
Screening of Lipid Metabolism-Related Genes as Diagnostic Indicators in Chronic Obstructive Pulmonary Disease., PMID:38046983
Screening and Bioinformatics Analysis of Differential Genes in Autism Spectrum Disorder Based on GEO Database., PMID:38007751
Analysis and experimental validation of fatty acid metabolism-related genes prostacyclin synthase (PTGIS) in endometrial cancer., PMID:37796199
Bioinformatics analysis to reveal the potential comorbidity mechanism in psoriasis and nonalcoholic steatohepatitis., PMID:37753698
Prostaglandin D2 regulates Escherichia coli-induced inflammatory responses through TLR2, TLR4, and NLRP3 in macrophages., PMID:37669705
miR-665 overexpression inhibits the apoptosis of luteal cells in small ruminants suppressing HPGDS., PMID:37178673
CRBN ligand expansion for hematopoietic prostaglandin D2 synthase (H-PGDS) targeting PROTAC design and their in vitro ADME profiles., PMID:37018877
Myricetin alleviated immunologic contact urticaria and mast cell degranulation via the PI3K/Akt/NF-κB pathway., PMID:36649930
Structure-activity relationship study of PROTACs against hematopoietic prostaglandin D2 synthase., PMID:36561070
Bioinformatics Prediction and Machine Learning on Gene Expression Data Identifies Novel Gene Candidates in Gastric Cancer., PMID:36553500
Exploring and validating the metastasis mechanism of pathenolide interfering with cutaneous melanoma through ER stress-dependent apoptosis based on the network pharmacology., PMID:36477977
Glutathione S-Transferases S1, Z1 and A1 Serve as Prognostic Factors in Glioblastoma and Promote Drug Resistance through Antioxidant Pathways., PMID:36291099
Identification of a six-gene prognostic signature for bladder cancer associated macrophage., PMID:36275756
Overexpressing HPGDS in adipose-derived mesenchymal stem cells reduces inflammatory state and improves wound healing in type 2 diabetic mice., PMID:35922870
Integration of transcriptomic and metabolomic reveals metabolic pathway alteration in earthworms (Eisenia fetida) under copper exposure., PMID:35753647
Interleukin-4 treatment reduces leukemia burden in acute myeloid leukemia., PMID:35471732
A peripheral lipid sensor GPR120 remotely contributes to suppression of PGD2-microglia-provoked neuroinflammation and neurodegeneration in the mouse hippocampus., PMID:34961526
Single-cell RNA sequencing of mouse left ventricle reveals cellular diversity and intercommunication., PMID:34859688
Monocytes and Macrophages Serve as Potent Prostaglandin D2 Sources during Acute, Non-Allergic Pulmonary Inflammation., PMID:34769126
Discovery of a Highly Potent and Selective Degrader Targeting Hematopoietic Prostaglandin D Synthase via In Silico Design., PMID:34652145
Hematopoietic Prostaglandin D Synthase Inhibitor PK007 Decreases Muscle Necrosis in DMD mdx Model Mice., PMID:34575143
Single-cell analysis pinpoints distinct populations of cytotoxic CD4+ T cells and an IL-10+CD109+ TH2 cell population in nasal polyps., PMID:34389612
Proteome and transcriptome analysis revealed florfenicol via affected drug metabolism and lipid metabolism induce liver injury of broilers., PMID:34293615
A knowledge-based, structural-aided discovery of a novel class of 2-phenylimidazo[1,2-a]pyridine-6-carboxamide H-PGDS inhibitors., PMID:33991628
In the mouse, prostaglandin D2 signalling protects the endometrium against adenomyosis., PMID:33851217
Development of a Hematopoietic Prostaglandin D Synthase-Degradation Inducer., PMID:33603969
Deletion of Alox15 improves kidney dysfunction and inhibits fibrosis by increased PGD2 in the kidney., PMID:33595729
Selective inhibition of prostaglandin D2 biosynthesis in human mast cells to overcome need for multiple receptor antagonists: Biochemical consequences., PMID:33449404
Novel amide and imidazole compounds as potent hematopoietic prostaglandin D2 synthase inhibitors., PMID:33383152
For research use only. Not for human or drug use.
