Catalog No.
YHA89801
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gly320-Arg454
Predicted molecular weight
17.80 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O60383
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Growth/differentiation factor 9, GDF-9, GDF9
Roles of GDF9 and BMP15 in equine follicular development: in vivo content and in vitro effects of IGF1 and cortisol on granulosa cells., PMID:40289073
Regulating human oocyte maturation in vitro: a hypothesis based on oocytes retrieved from small antral follicles during ovarian tissue cryopreservation., PMID:40261459
Impact of female age on concentrations of reproductive hormones and oocyte-specific growth factors in follicular fluid from human small antral follicles., PMID:39922201
Pro-cumulin addition in a biphasic in vitro oocyte maturation system modulates human oocyte and cumulus cell transcriptomes., PMID:39862403
Combination of FSH and testosterone could enhance activation of primordial follicles and growth of activated follicles in 1-day-old mice ovaries in vitro cultured for 12 days., PMID:39710995
Oocyte-derived growth differentiation factor 9 suppresses the expression of CYP17A1 and androgen production in human theca cells., PMID:39382269
Novel Insight into the mechanism of di (2-ethylhexyl) phthalate (DEHP) impairing early follicle development., PMID:39293100
Revisiting GDF9 variants in primary ovarian insufficiency: A shift from dominant to recessive pathogenicity?, PMID:38942181
Prenatal acetaminophen exposure and the developing ovary: Time, dose, and course consequences for fetal mice., PMID:38657942
GDF9His209GlnfsTer6/S428T and GDF9Q321X/S428T bi-allelic variants caused female subfertility with defective follicle enlargement., PMID:38643161
In-vitro generation of follicle-like structures from human germ cell-like cells derived from theca stem cell combined with ovarian somatic cells., PMID:38167472
Interleukin 17 and Growth Differentiation Factor 9 Influence in a Sample of Iraqi Infertile Males., PMID:38028840
Implication of Novel BMP15 and GDF9 Variants in Unexpected Poor Ovarian Response., PMID:37848645
Decreased growth differentiation factor 9, bone morphogenetic protein 15, and forkhead box O3a expressions in the ovary via ulipristal acetate., PMID:37585996
Decreased GDF9 and BMP15 in follicle fluid and granulosa cells and outcomes of IVF-ET among young patients with low prognosis., PMID:36689045
Resolving the challenge of insoluble production of mature human growth differentiation factor 9 protein (GDF9) in E. coli using bicistronic expression with thioredoxin., PMID:36649874
Oocyte-Secreted Serum Biomarkers GDF9 and BMP15 in Women with Endometriosis., PMID:36380138
Serum GDF9 and BMP15 as potential markers of ovarian function in women with and without polycystic ovary syndrome., PMID:36372988
Concentrations of oocyte secreted GDF9 and BMP15 decrease with MII transition during human IVM., PMID:35986324
Intrafollicular Concentrations of the Oocyte-secreted Factors GDF9 and BMP15 Vary Inversely in Polycystic Ovaries., PMID:35511085
Sitagliptin/metformin improves the fertilization rate and embryo quality in polycystic ovary syndrome patients through increasing the expression of GDF9 and BMP15: A new alternative to metformin (a randomized trial)., PMID:35217236
The boosting effects of melatonin on the expression of related genes to oocyte maturation and antioxidant pathways: a polycystic ovary syndrome- mouse model., PMID:35057828
Ovarian insufficiency and secondary amenorrhea in a patient with a novel variant within GDF9 gene., PMID:35013061
Effect of cumulin and super-GDF9 in standard and biphasic mouse IVM., PMID:34984599
A frameshift deletion in the GDF9 gene in Icelandic Loa prolific sheep., PMID:34967038
CPEB3 deficiency in mice affect ovarian follicle development and causes premature ovarian insufficiency., PMID:34930897
GDF9 concentration in embryo culture medium is linked to human embryo quality and viability., PMID:34845575
Regulation of GDF9 and CDKN1B expression in Tibetan sheep testes during different stages of maturity., PMID:34826605
Taurine improves follicular survival and function of mice ovarian grafts through increasing CD31 and GDF9 expression and reducing oxidative stress and apoptosis., PMID:33940031
Abnormal early folliculogenesis due to impeded pyruvate metabolism in mouse oocytes†., PMID:33824958
A homozygous truncating variant in GDF9 in siblings with primary ovarian insufficiency., PMID:33797006
Exploratory analysis of serum concentrations of oocyte biomarkers growth differentiation factor 9 and bone morphogenetic protein 15 in ovulatory women across the menstrual cycle., PMID:33775397
New insights into the GDF9-Hedgehog-GLI signaling pathway in human ovaries: from fetus to postmenopause., PMID:33772413
Single-cell transcriptome dissection of the toxic impact of Di (2-ethylhexyl) phthalate on primordial follicle assembly., PMID:33754040
Association of FSHR, LH, LHR, BMP15, GDF9, AMH, and AMHR polymorphisms with poor ovarian response in patients undergoing in vitro fertilization., PMID:33739800
Polymorphism Detection of GDF9 Gene and Its Association with Litter Size in Luzhong Mutton Sheep (Ovis aries)., PMID:33671790
Activation-induced cytidine deaminase is a possible regulator of cross-talk between oocytes and granulosa cells through GDF-9 and SCF feedback system., PMID:33589683
Genetic etiologic analysis in 74 Chinese Han women with idiopathic premature ovarian insufficiency by combined molecular genetic testing., PMID:33538981
Age-related decline in the expression of GDF9 and BMP15 genes in follicle fluid and granulosa cells derived from poor ovarian responders., PMID:33397408
New insights into the genetic basis of premature ovarian insufficiency: Novel causative variants and candidate genes revealed by genomic sequencing., PMID:33036707
The Effect of Isotretinoin on Oocyte Maturation in Adolescent Female Rats., PMID:32894850
GDF9 polymorphisms: influence on ovarian response in women undergoing controlled ovarian hyperstimulation., PMID:32510893
A variant of human growth differentiation factor-9 that improves oocyte developmental competence., PMID:32350111
Prediction of ovarian aging using ovarian expression of BMP15, GDF9, and C-KIT., PMID:32223330
Rapamycin preserves the primordial follicle pool during cisplatin treatment in vitro and in vivo., PMID:32112509
Growth differentiation factor 9 inhibits vascular endothelial growth factor expression in human granulosa cells., PMID:31996061
The antioxidant curcumin postpones ovarian aging in young and middle-aged mice., PMID:31656219
The role of BMP15 and GDF9 in the pathogenesis of primary ovarian insufficiency., PMID:31607184
Regulation of Insulin-Like Growth Factor 2 by Oocyte-Secreted Factors in Primary Human Granulosa Cells., PMID:31588501
Association of BMP15 and GDF9 variants to premature ovarian insufficiency., PMID:31392662
For research use only. Not for human or drug use.
