Catalog No.
YHA85601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Lys501-Asn736
Predicted molecular weight
28.52 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O60266
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Adenylate cyclase type 3, Adenylyl cyclase 3, AC-III, Adenylate cyclase type III, AC3, KIAA0511, ADCY3, Adenylate cyclase, olfactive type, ATP pyrophosphate-lyase 3
A Mutation in the Transmembrane Domain of Adenylate Cyclase 3 Impairs Enzymatic Function to Cause Sex-Specific Depression- and Anxiety-Like Behaviors and Food Seeking in a Rat Model., PMID:40492272
GPR45 modulates Gαs at primary cilia of the paraventricular hypothalamus to control food intake., PMID:40472089
Regulation of perinatal estrogen levels on primordial follicle formation and activation in mouse., PMID:40261643
A mutation in the transmembrane domain of Adenylate cyclase 3 impairs enzymatic function to cause sex-specific depression- and anxiety-like behaviors and food seeking in a rat model., PMID:40236087
Association between polymorphisms of the adenylate cyclase 3 gene rs2241759 and the effect of high-intensity interval training on blood lipid profiles., PMID:40231066
Elucidating prognostic significance of purine metabolism in colorectal cancer through integrating data from transcriptomic, immunohistochemical, and single-cell RNA sequencing analysis., PMID:40017120
A novel golgi related genes based correlation prognostic index can better predict the prognosis of glioma and responses to immunotherapy., PMID:39976877
Signal Transduction Pathway Mediating Carotid Body Dependent Sympathetic Activation and Hypertension by Chronic Intermittent Hypoxia., PMID:39844350
[Association between ADCY3 gene polymorphism and the effects of high-intensity interval training on body composition]., PMID:39780573
Effects of Gene-Lifestyle Interaction on Obesity Among Students., PMID:39766774
Network-based meta-analysis and confirmation of genes ATP1A2, FXYD1, and ADCY3 associated with cAMP signaling in breast tumors compared to corresponding normal marginal tissues., PMID:39707785
Protein-coding mutation in Adcy3 increases adiposity and alters emotional behaviors sex-dependently in rats., PMID:39632398
Functional Evaluation of a Novel Homozygous ADCY3 Variant Causing Childhood Obesity., PMID:39519366
Ciliary localization of GPR75 promotes fat accumulation in mice., PMID:39352389
Neuronal LAMP2A-mediated reduction of adenylyl cyclases induces acute neurodegenerative responses and neuroinflammation after ischemic stroke., PMID:39341961
Dietary "Beigeing" Fat Contains More Phosphatidylserine and Enhances Mitochondrial Function while Counteracting Obesity., PMID:39329159
Central regulation of feeding and body weight by ciliary GPR75., PMID:39137039
The association between dietary, physical activity and the DNA methylation of PPARGC1A, HLA-DQA1 and ADCY3 in pregnant women with gestational diabetes mellitus: a nest case-control study., PMID:39060963
Protein-coding mutation in Adcy3 increases adiposity and alters emotional behaviors sex-dependently in rats., PMID:38916175
Whole Exome Sequencing Revealed Paternal Inheritance of Obesity-related Genetic Variants in a Family with an Exclusively Breastfed Infant., PMID:38915195
The Molecular Basis of Olfactory Dysfunction in COVID-19 and Long COVID., PMID:38749402
GDF15 controls primary cilia morphology and function thereby affecting progenitor proliferation., PMID:38719753
Cold-induced expression of a truncated adenylyl cyclase 3 acts as rheostat to brown fat function., PMID:38684889
Mendelian Randomization Analysis Identifies Inverse Causal Relationship between External Eating and Metabolic Phenotypes., PMID:38674857
Postnatal Dynamic Ciliary ARL13B and ADCY3 Localization in the Mouse Brain., PMID:38334651
CLCF1 inhibits energy expenditure via suppressing brown fat thermogenesis., PMID:38190531
Adenylate cyclase 3: a potential genetic link between obesity and major depressive disorder., PMID:37955134
Illuminating (HTLV-1)-induced adult T-cell leukemia/lymphoma transcriptomic signature: A systems virology approach., PMID:37832654
Hypoxia sensing requires H2S-dependent persulfidation of olfactory receptor 78., PMID:37406126
The Effects of the Levels of Hypoxia in the Olfactory Nervous System in Mouse Model., PMID:37350017
Understanding the Genetics of Early-Onset Obesity in a Cohort of Children From Qatar., PMID:37329217
GWAS-Identified Variants for Obesity Do Not Influence the Risk of Developing Multiple Myeloma: A Population-Based Study and Meta-Analysis., PMID:37047000
Association of Plant-Based and High-Protein Diets with a Lower Obesity Risk Defined by Fat Mass in Middle-Aged and Elderly Persons with a High Genetic Risk of Obesity., PMID:36839421
Next-generation sequencing of 12 obesity genes in a Portuguese cohort of patients with overweight and obesity., PMID:36775011
Energy Trade-off and 4 Extreme Human Body Types., PMID:36413496
Effects of berberine hydrochloride on immune response in the crab Charybdis japonica., PMID:35953779
RNA modification-related variants in genomic loci associated with body mass index., PMID:35879730
Chronic intermittent hypoxia impacts the olfactory nervous system in an age-dependent manner: pilot study., PMID:35780199
Expression Regulation of Water Reabsorption Genes and Transcription Factors in the Kidneys of Lepus yarkandensis., PMID:35721542
REEP6 knockout leads to defective β-adrenergic signaling in adipocytes and promotes obesity-related metabolic dysfunction., PMID:35150731
NF-κB-Related Metabolic Gene Signature Predicts the Prognosis and Immunotherapy Response in Gastric Cancer., PMID:35036435
The Spectrum of Genetic Variants Associated with the Development of Monogenic Obesity in Qatar., PMID:35026759
Molecular modelling of novel ADCY3 variant predicts a molecular target for tackling obesity., PMID:34821371
Weighted gene co-expression network analysis to identify key modules and hub genes associated with paucigranulocytic asthma., PMID:34727921
Regulation of Brain Primary Cilia Length by MCH Signaling: Evidence from Pharmacological, Genetic, Optogenetic, and Chemogenic Manipulations., PMID:34665407
The potential cytotoxic effects of urban particle matter on olfaction., PMID:34636368
ALDH2, ADCY3 and BCMO1 polymorphisms and lifestyle-induced traits are jointly associated with CAD risk in Chinese Han people., PMID:34481002
Molecular mechanism of reproductive toxicity induced by Tripterygium Wilfordii based on network pharmacology., PMID:34232166
Epigenome-Wide Study Identified Methylation Sites Associated with the Risk of Obesity., PMID:34207686
Identifying molecular pathways and candidate genes associated with knob traits by transcriptome analysis in the goose (Anser cygnoides)., PMID:34099774
For research use only. Not for human or drug use.
