Catalog No.
YHA79101
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gly42-Ser266
Predicted molecular weight
27.45 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O43819
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Protein SCO2 homolog, mitochondrial, SCO2
Construction and evaluation of a neonatal septic shock prediction model based on multimodal data., PMID:40489824
Clioquinol induces mitochondrial toxicity in SH-SY5Y neuroblastoma cells by affecting the respiratory chain complex IV and OPA1 dynamin-like GTPase., PMID:40125820
Unraveling the genetic mysteries of spinal muscular atrophy in Chinese families., PMID:39815358
Roles of Copper Transport Systems Members in Breast Cancer., PMID:39676279
The variegated canalized-1 tomato mutant is linked to photosystem assembly., PMID:39582891
Interpretation of molecular autopsy findings in 45 sudden unexplained death cases: from coding region to untranslated region., PMID:39266800
p53 Orchestrates Cancer Metabolism: Unveiling Strategies to Reverse the Warburg Effect., PMID:39207627
Streamlining Skin Regeneration: A Ready-To-Use Silk Bilayer Wound Dressing., PMID:39057462
FERMT1 suppression induces anti-tumor effects and reduces stemness in glioma cancer cells., PMID:38976072
Influence of the interaction between p53 and ZNF568 on mitochondrial oxidative phosphorylation., PMID:38944084
Targeting mitochondrial bioenergetics by combination treatment with imatinib and dichloroacetate in human erythroleukemic K‑562 and colorectal HCT‑116 cancer cells., PMID:38426621
Repeated radon exposure induced epithelial-mesenchymal transition-like transformation via disruption of p53-dependent mitochondrial function., PMID:38145089
Decoding the mitochondrial connection: development and validation of biomarkers for classifying and treating systemic lupus erythematosus through bioinformatics and machine learning., PMID:38044432
Identification of biomarkers associated with pediatric asthma using machine learning algorithms: A review., PMID:38013370
Brain Gene Co-Expression Network Analysis Identifies 22q13 Region Genes Associated with Autism, Intellectual Disability, Seizures, Language Impairment, and Hypotonia., PMID:38002941
Techno-economic and environmental optimization of a combined regenerated gas turbine and supercritical CO2 cycle based on methane and hydrogen mixture as fuel for environmental remediation., PMID:37482316
Hepatic depletion of nucleolar protein mDEF causes excessive mitochondrial copper accumulation associated with p53 and NRF1 activation., PMID:37456842
Cancer-cell-secreted extracellular vesicles target p53 to impair mitochondrial function in muscle., PMID:37439436
Tri-objective optimization of a waste-to-energy plant with super critical carbon dioxide and multi-effect water desalination for building application based on biomass fuels., PMID:37302493
Identification and validation of hub genes and pathways associated with mitochondrial dysfunction in hypertrophy of ligamentum flavum., PMID:37234868
Copper metabolism in cell death and autophagy., PMID:37055935
Counteracting Colon Cancer by Inhibiting Mitochondrial Respiration and Glycolysis with a Selective PKCδ Activator., PMID:36982784
Mitochondrial respiration reduces exposure of the nucleus to oxygen., PMID:36796514
Protein Transduction Domain-Mediated Delivery of Recombinant Proteins and In Vitro Transcribed mRNAs for Protein Replacement Therapy of Human Severe Genetic Mitochondrial Disorders: The Case of Sco2 Deficiency., PMID:36678915
Leigh Syndrome: Spectrum of Molecular Defects and Clinical Features in Russia., PMID:36675121
Identify Biomarkers and Design Effective Multi-Target Drugs in Ovarian Cancer: Hit Network-Target Sets Model Optimizing., PMID:36552360
The expression of cuproptosis-related genes in hepatocellular carcinoma and their relationships with prognosis., PMID:36313717
Pan-cancer genetic analysis of cuproptosis and copper metabolism-related gene set., PMID:36276096
FKBP4 regulates 5-fluorouracil sensitivity in colon cancer by controlling mitochondrial respiration., PMID:35981890
Mitochondrial complex IV defects induce metabolic and signaling perturbations that expose potential vulnerabilities in HCT116 cells., PMID:35302710
Mitochondrial COA7 is a heme-binding protein with disulfide reductase activity, which acts in the early stages of complex IV assembly., PMID:35210360
Identification of a novel homozygous synthesis of cytochrome c oxidase 2 variant in siblings with early-onset axonal Charcot-Marie-Tooth disease., PMID:35112411
The Role of COA6 in the Mitochondrial Copper Delivery Pathway to Cytochrome c Oxidase., PMID:35053273
Mutational screening of AGRN, SLC39A5, SCO2, P4HA2, BSG, ZNF644, and CPSF1 in a Chinese cohort of 103 patients with nonsyndromic high myopia., PMID:35002215
Expression of SCO1 and SCO2 after form-deprivation myopia in Guinea pigs., PMID:34962434
SOD1 mutations cause hypersensitivity to high-pressure-induced oxidative stress in Saccharomyces cerevisiae., PMID:34728328
The function of Scox in glial cells is essential for locomotive ability in Drosophila., PMID:34707123
Development of a novel PTD-mediated IVT-mRNA delivery platform for potential protein replacement therapy of metabolic/genetic disorders., PMID:34703653
TCF19 and p53 regulate transcription of TIGAR and SCO2 in HCC for mitochondrial energy metabolism and stress adaptation., PMID:34369624
The Modulation of PCSK9 and LDLR by Supercritical CO2 Extracts of Mentha longifolia and Isolated Piperitone Oxide, an In Vitro Study., PMID:34202378
Assessment of postoperative risk factors for EEG abnormalities in routine clinical management after paediatric cardiopulmonary bypass., PMID:33822951
Bi-allelic loss of function variants in COX20 gene cause autosomal recessive sensory neuronopathy., PMID:33751098
Differential mass spectrometry-based proteome analyses unveil major regulatory hubs in rifamycin B production in Amycolatopsis mediterranei., PMID:33662614
In vivo biodistribution study of TAT-L-Sco2 fusion protein, developed as protein therapeutic for mitochondrial disorders attributed to SCO2 mutations., PMID:33318931
The antioxidant function of Sco proteins depends on a critical surface-exposed residue., PMID:33171213
Effect of low vs high haemoglobin transfusion trigger on cardiac output in patients undergoing elective vascular surgery: Post-hoc analysis of a randomized trial., PMID:33141936
Cardio-centric hemodynamic management improves spinal cord oxygenation and mitigates hemorrhage in acute spinal cord injury., PMID:33060602
Graded reductions in pre-exercise glycogen concentration do not augment exercise-induced nuclear AMPK and PGC-1α protein content in human muscle., PMID:32862503
Recurrent sequence evolution after independent gene duplication., PMID:32770961
For research use only. Not for human or drug use.
