Catalog No.
YHA76601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Lys17-Lys260
Predicted molecular weight
29.51 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O43741
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
AMPK subunit beta-2, PRKAB2, 5'-AMP-activated protein kinase subunit beta-2
Brain Transcriptome Changes Associated With an Acute Increase of Protein O-GlcNAcylation and Implications for Neurodegenerative Disease., PMID:39823370
Identification and Functional Analysis of Ras-Related Associated with Diabetes Gene (rrad) in Edwardsiella piscicida-Resistant Individuals of Japanese Flounder (Paralichthys olivaceus)., PMID:39408905
A genetic-epigenetic interplay at 1q21.1 locus underlies CHD1L-mediated vulnerability to primary progressive multiple sclerosis., PMID:39079955
Variances in the Expression Profile of Circadian Clock-Related Genes in Astrocytic Brain Tumors., PMID:39001398
Human Genetics of Ventricular Septal Defect., PMID:38884729
Maternal Diet High in Linoleic Acid Alters Renal Branching Morphogenesis and mTOR/AKT Signalling Genes in Rat Fetal Kidneys., PMID:38731907
Ontogeny of hepatic metabolism in two broiler lines divergently selected for the ultimate pH of the Pectoralis major muscle., PMID:38698322
Low PRKAB2 Expression Is Associated with Poor Outcomes in Pediatric Adrenocortical Tumors, and Treatment with Rottlerin Increases the PRKAB2 Level and Inhibits Tumorigenic Aspects in the NCI-H295R Adrenocortical Cancer Cell Line., PMID:38539429
MiR-29b Alleviates High Glucose-induced Inflammation and Apoptosis in Podocytes by Down-regulating PRKAB2., PMID:38204237
Transcriptome analysis to identify candidate genes related to mammary gland development of Bactrian camel (Camelus bactrianus)., PMID:37342620
Investigation of cytotoxic and apoptotic effects of disodium pentaborate decahydrate on ovarian cancer cells and assessment of gene profiling., PMID:36308567
AMP-activated protein kinase β1 or β2 deletion enhances colon cancer cell growth and tumorigenesis., PMID:35880569
H19 inhibition increases HDAC6 and regulates IRS1 levels and insulin signaling in the skeletal muscle during diabetes., PMID:35842608
miR-1227-3p participates in the development of fetal growth restriction via regulating trophoblast cell proliferation and apoptosis., PMID:35430618
Association Analysis of LEP Signaling Pathway with Type 2 Diabetes Mellitus in Chinese Han Population from South China., PMID:34589546
Urate-induced epigenetic modifications in myeloid cells., PMID:34321071
Selenium triggers Nrf2-AMPK crosstalk to alleviate cadmium-induced autophagy in rabbit cerebrum., PMID:34252479
RNA sequencing reveals potential interacting networks between the altered transcriptome and ncRNome in the skeletal muscle of diabetic mice., PMID:34190986
A novel autophagy-related genes prognostic risk model and validation of autophagy-related oncogene VPS35 in breast cancer., PMID:34001111
TNF-induced necroptosis initiates early autophagy events via RIPK3-dependent AMPK activation, but inhibits late autophagy., PMID:33779513
Development and Validation of a 5-Gene Autophagy-Based Prognostic Index in Endometrial Carcinoma., PMID:33577492
AMPKβ1 and AMPKβ2 define an isoform-specific gene signature in human pluripotent stem cells, differentially mediating cardiac lineage specification., PMID:33454005
[Partial isoform-specific expression and function of AMPK in ovarian carcinoma]., PMID:32727648
Metformin ameliorates animal models of dermatitis., PMID:32347398
Impact of short- and long-term electrically induced muscle exercise on gene signaling pathways, gene expression, and PGC1a methylation in men with spinal cord injury., PMID:31869286
Detection of a familial 1q21.1 microdeletion and concomitant CHD1L mutation in a fetus with oligohydramnios and bilateral renal dysplasia on prenatal ultrasound., PMID:31759543
The study of copy number variations in the regions of PRKAB2 and PPM1K among congenital heart defects patients., PMID:31340305
AMP-activated protein kinase complexes containing the β2 regulatory subunit are up-regulated during and contribute to adipogenesis., PMID:31189568
Coexpression network analysis of platelet genes in sickle cell disease., PMID:30663491
Biological Pathways Leading From ANGPTL8 to Diabetes Mellitus-A Co-expression Network Based Analysis., PMID:30627105
AMPK signaling linked to the schizophrenia-associated 1q21.1 deletion is required for neuronal and sleep maintenance., PMID:30566533
Identification of tumor-educated platelet biomarkers of non-small-cell lung cancer., PMID:30532555
Prolonged incubation with Metformin decreased angiogenic potential in human bone marrow mesenchymal stem cells., PMID:30372835
A Novel Dnmt3a1 Transcript Inhibits Adipogenesis., PMID:30333755
Long-term Dietary Macronutrients and Hepatic Gene Expression in Aging Mice., PMID:29688281
Maternal Melatonin Therapy Attenuated Maternal High-Fructose Combined with Post-Weaning High-Salt Diets-Induced Hypertension in Adult Male Rat Offspring., PMID:29641494
The role of AMP-activated protein kinase in the expression of the dystrophin-associated protein complex in skeletal muscle., PMID:29401588
Methyl-β-cyclodextrin restores impaired autophagy flux in Niemann-Pick C1-deficient cells through activation of AMPK., PMID:28613987
The codon 72 polymorphism of p53 influences cell fate following nutrient deprivation., PMID:28475405
Characterisation of equine satellite cell transcriptomic profile response to β-hydroxy-β-methylbutyrate (HMB)., PMID:27691998
When phosphorylated at Thr148, the β2-subunit of AMP-activated kinase does not associate with glycogen in skeletal muscle., PMID:27099349
AMP-activated protein kinase: a cellular energy sensor that comes in 12 flavours., PMID:26934201
The interaction between AMPKβ2 and the PP1-targeting subunit R6 is dynamically regulated by intracellular glycogen content., PMID:26831516
Probing the enzyme kinetics, allosteric modulation and activation of α1- and α2-subunit-containing AMP-activated protein kinase (AMPK) heterotrimeric complexes by pharmacological and physiological activators., PMID:26635351
AMPK Promotes Aberrant PGC1β Expression To Support Human Colon Tumor Cell Survival., PMID:26351140
Muscle-specific AMPK β1β2-null mice display a myopathy due to loss of capillary density in nonpostural muscles., PMID:24522207
Sumoylation of AMPKβ2 subunit enhances AMP-activated protein kinase activity., PMID:23552691
Control of tumor bioenergetics and survival stress signaling by mitochondrial HSP90s., PMID:22975376
AMP-activated protein kinase regulation and biological actions in the heart., PMID:22935535
Over-expressions of AMPK subunits in ovarian carcinomas with significant clinical implications., PMID:22897928
For research use only. Not for human or drug use.
