Catalog No.
YHA68901
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Ser91
Predicted molecular weight
12.38 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O43504
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
HBX-interacting protein, Late endosomal/lysosomal adaptor and MAPK and MTOR activator 5, HBXIP, LAMTOR5, HBV X-interacting protein, XIP, Ragulator complex protein LAMTOR5, Hepatitis B virus X-interacting protein
Exploring proteomic immunoprofiles: common neurological and immunological pathways in multiple sclerosis and type 1 diabetes mellitus., PMID:39901093
IL-7 promotes integrated glucose and amino acid sensing during homeostatic CD4+ T cell proliferation., PMID:39799568
Proteomic Analysis of Vibrio parahaemolyticus-Stimulated Pinctada martensii Proteins for Antimicrobial Activity, Potential Mechanisms, and Key Components., PMID:39596793
Oncoprotein LAMTOR5-mediated CHOP silence via DNA hypermethylation and miR-182/miR-769 in promotion of liver cancer growth., PMID:38942954
HBXIP induces PARP1 via WTAP-mediated m6A modification and CEBPA-activated transcription in cisplatin resistance to hepatoma., PMID:38871923
mTORC1-CTLH E3 ligase regulates the degradation of HMG-CoA synthase 1 through the Pro/N-degron pathway., PMID:38788716
Defective Lamtor5 Leads to Autoimmunity by Deregulating v-ATPase and Lysosomal Acidification., PMID:38639386
Research progress on oncoprotein hepatitis B X‑interacting protein (Review)., PMID:38577934
Transcriptome analysis of skeletal muscle in dermatomyositis, polymyositis, and dysferlinopathy, using a bioinformatics approach., PMID:38125829
Proteomic Analysis by 4D Label-free MS-PRM Provides Insight into the Role and Regulatory Mechanisms of IL-25 in NK Cells., PMID:37702163
Integrative analysis of circadian clock with prognostic and immunological biomarker identification in ovarian cancer., PMID:37409345
Establishment and validation of the autophagy-related ceRNA network in irreversible pulpitis., PMID:37208635
Non-coding RNAs are correlated to TGF-β receptor type 2 in patients with colorectal cancer., PMID:36579810
The analysis of the pyroptosis-related genes and hub gene TP63 ceRNA axis in osteosarcoma., PMID:36389801
Sorafenib triggers ferroptosis via inhibition of HBXIP/SCD axis in hepatocellular carcinoma., PMID:36109580
Identification of key genes and pathways associated with sex difference in osteoarthritis based on bioinformatics analysis., PMID:36046996
Multiplexed Human Gene Expression Analysis Reveals a Central Role of the TLR/mTOR/PPARγ and NFkB Axes in Burn and Inhalation Injury-Induced Changes in Systemic Immunometabolism and Long-Term Patient Outcomes., PMID:36012680
Hbxip is essential for murine embryogenesis and regulates embryonic stem cell differentiation through activating mTORC1., PMID:35608036
HBXIP is a novel regulator of the unfolded protein response that sustains tamoxifen resistance in ER+ breast cancer., PMID:35093383
LAMTOR5-AS1 regulates chemotherapy-induced oxidative stress by controlling the expression level and transcriptional activity of NRF2 in osteosarcoma cells., PMID:34862368
High HBXIP expression is related to poor prognosis in HCC by extensive database interrogation., PMID:34730200
Long Noncoding RNA LAMTOR5-AS1 Interference Affects MicroRNA-506-3p/E2F6-Mediated Behavior of Non-Small Cell Lung Cancer Cells., PMID:34588094
Down-Regulation of HBXIP Inhibits Non-Small Cell Lung Cancer Growth and Enhances the Anti-Tumor Immunity of Mice by Reducing NRP-1., PMID:34452886
LAMTOR5 expression level is a biomarker for colorectal cancer and lncRNA LAMTOR5-AS1 predicting miRNA sponging effect., PMID:34374893
HBXIP accelerates glycolysis and promotes cancer angiogenesis via AKT/mTOR pathway in bladder cancer., PMID:34216584
The modulation of PD-L1 induced by the oncogenic HBXIP for breast cancer growth., PMID:33824459
Oncoprotein HBXIP promotes tumorigenesis through MAPK/ERK pathway activation in non-small cell lung cancer., PMID:33628588
The oncogenic role of HBXIP., PMID:33378953
HBXIP drives metabolic reprogramming in hepatocellular carcinoma cells via METTL3-mediated m6A modification of HIF-1α., PMID:33305825
Germacrone Regulates HBXIP-Mediated Cell Cycle, Apoptosis and Promotes the Formation of Autophagosomes to Inhibit the Proliferation of Gastric Cancer Cells., PMID:33244453
HBXIP promotes gastric cancer via METTL3-mediated MYC mRNA m6A modification., PMID:33048840
Quantitative genetic screening reveals a Ragulator-FLCN feedback loop that regulates the mTORC1 pathway., PMID:32934076
Dynamic Palmitoylation of the Sodium-Calcium Exchanger Modulates Its Structure, Affinity for Lipid-Ordered Domains, and Inhibition by XIP., PMID:32521252
The regulation of acetylation and stability of HMGA2 via the HBXIP-activated Akt-PCAF pathway in promotion of esophageal squamous cell carcinoma growth., PMID:32313942
Identification of Specific Long Non-Coding Ribonucleic Acid Signatures and Regulatory Networks in Prostate Cancer in Fine-Needle Aspiration Biopsies., PMID:32117463
HBXIP: a potential prognosis biomarker of colorectal cancer which promotes invasion and migration via epithelial-mesenchymal transition., PMID:31987874
LAMTOR5 raises abnormal initiation of O-glycosylation in breast cancer metastasis via modulating GALNT1 activity., PMID:31836847
The coding and non-coding transcriptional landscape of subependymal giant cell astrocytomas., PMID:31834371
Trilobatin, a Novel SGLT1/2 Inhibitor, Selectively Induces the Proliferation of Human Hepatoblastoma Cells., PMID:31540429
The metabolic regulator Lamtor5 suppresses inflammatory signaling via regulating mTOR-mediated TLR4 degradation., PMID:31467416
Increased Expression of LAMTOR5 Predicts Poor Prognosis and Is Associated with Lymph Node Metastasis of Head and Neck Squamous Cell Carcinoma., PMID:31337951
Oncoprotein LAMTOR5 Activates GLUT1 Via Upregulating NF-κB in Liver Cancer., PMID:30847404
The oncoprotein HBXIP competitively binds KEAP1 to activate NRF2 and enhance breast cancer cell growth and metastasis., PMID:30692632
HBXIP protein overexpression predicts the poor prognosis of pancreatic ductal adenocarcinomas., PMID:30583814
MiR-145-targeted HBXIP modulates human breast cancer cell proliferation., PMID:30381907
Oncogenic HBXIP enhances ZEB1 through Sp1 to accelerate breast cancer growth., PMID:30273966
The oncoprotein HBXIP promotes human breast cancer growth through down-regulating p53 via miR-18b/MDM2 and pAKT/MDM2 pathways., PMID:30181579
Oncoprotein HBXIP induces PKM2 via transcription factor E2F1 to promote cell proliferation in ER-positive breast cancer., PMID:29925919
Oncoprotein HBXIP enhances HOXB13 acetylation and co-activates HOXB13 to confer tamoxifen resistance in breast cancer., PMID:29471853
HBXIP activates the PPARδ/NF-κB feedback loop resulting in cell proliferation., PMID:29416623
For research use only. Not for human or drug use.
