Catalog No.
YHA68101
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Leu352-Phe513
Predicted molecular weight
21.01 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O43474
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
KLF4, Gut-enriched krueppel-like factor, Krueppel-like factor 4, EZF, GKLF, Epithelial zinc finger protein EZF
Transmembrane Protease Serine 11B Modulates Lactate Transport Through SLC16A1 in Pancreatic Ductal Adenocarcinoma-A Functional Link to Phenotype Heterogeneity., PMID:40508207
Ano5 Deficiency Leads to Abnormal Bone Formation via miR-34c-5p/KLF4/β-Catenin in Gnathodiaphyseal Dysplasia., PMID:40508076
Upregulation of TLR-MYD88 signaling, stem cell genes, and Klotho mediates sepsis-associated myocardial inflammation., PMID:40504431
KLF4 mediates the contradictory effects of phenylethyl isothiocyanate in gastric cancer intervention., PMID:40504295
Scoparone Alleviates Aortic Aneurysm Formation by Inhibiting Smooth Muscle Cell Phenotypic Switching and Inflammation via mTOR Suppression., PMID:40490231
MCPIP1 deficiency alleviates abdominal aortic aneurysm formation by inhibiting MAPK signaling., PMID:40479739
The protective effect of iron isomaltoside on myocardial ischemia-reperfusion injury via the suppression of KLF4/NF-κB signaling., PMID:40471885
The Impacts of TNF-α-Induced Inflammation on Amnion Epithelial Cells: Exploring Stem Cell Gene Expression, Senescence, Inflammatory Responses, and Cellular Transition., PMID:40454815
Role of super-enhancer-associated miRNAs and histone modifications in intramuscular fat deposition in yak., PMID:40451366
Exosome-derived SLC12A2-DT promotes macrophage M2 polarization-mediated hepatocellular carcinoma progression., PMID:40446695
A Novel Function of NaV Channel β3 Subunit in Endothelial Cell Alignment Through Autophagy Modulation., PMID:40445729
Somatic cell reprogramming from different origins and donors into iPSC, with four factors OSKM using viral Sendai vectors., PMID:40424951
Pharmacological and toxicological roles of Kruppel-like factors (KLFs) in the cardiovascular system: a review., PMID:40418318
Synergistic effects of micropatterned substrates and transforming growth factor-β1 on differentiation of human mesenchymal stem cells into vascular smooth muscle cells through modulation of Krϋppel-like factor 4., PMID:40408054
Viral-mediated Pou5f1 (Oct4) overexpression and inhibition of Notch signaling synergistically induce neurogenic competence in mammalian Müller glia., PMID:40388211
Lactylation-boosted polycomb repression of KLF4 elicits glycolysis in retinoblastoma: A positive feedback circuit between histone modifications., PMID:40383410
Induction of feline fetal fibroblasts into pluripotent stem cells using cat-derived reprogramming factors., PMID:40381593
Novel carbazole attenuates vascular remodeling through STAT3/CIAPIN1 signaling in vascular smooth muscle cells., PMID:40370537
Silencing KRIT1 Partially Reverses the Effects of Disturbed Flow on the Endothelial Cell Transcriptome., PMID:40362576
Wisent Somatic Cells Resist Reprogramming by the PiggyBac Transposon System: A Case Study Highlighting Methodological and Conservation Hurdles., PMID:40362564
Induction of T-Cell Differentiation by KLF4 in T-Cell Acute Lymphoblastic Leukemia Cells Harboring Activating Mutation in NOTCH3., PMID:40354086
(-)-Epicatechin regulates the resistance of lung adenocarcinoma cells to radiotherapy through the downregulation of FOXM1., PMID:40335843
Modulating Cancer Stem Cell Characteristics in CD133+ Melanoma Cells through Hif1α, KLF4, and SHH Silencing., PMID:40321496
The role of KLF4 in phagocyte activation during infectious diseases., PMID:40313940
Role of KLF5 in enhancing ovarian cancer stemness and PARPi resistance: mechanisms and therapeutic targeting., PMID:40307891
Heterogenous cancer-associated fibroblasts related tumor microenvironment marked by CD10/KLF4/TIAM1 were identified in pancreatic adenocarcinoma by integrated transcriptomics., PMID:40303408
Gene expression profiling, prognosis, and immune microenvironment of KLF4 in malignancies., PMID:40299916
NEUROD1 efficiently converts peripheral blood cells into neurons with partial reprogramming by pluripotency factors., PMID:40299704
Integrative DNA methylome and transcriptome analysis identify potential genes on the influence of dilated cardiomyopathy-associated heart failure., PMID:40296161
FTO-mediated m6A demethylation of KLF4 promotes the proliferation and collagen deposition of keloid fibroblasts., PMID:40291597
Isolation and Culture of Primary Pericytes from Mouse., PMID:40291426
Generation and Characterization of a Human-Derived iPSC line from a female child with First-Episode of sporadic schizophrenia., PMID:40280000
EEPD1 regulates inflammation and endothelial apoptosis in atherosclerosis through KLF4-EEPD1-ERK axis., PMID:40268512
METTL14 promotes intimal hyperplasia through m6A-mediated control of vascular smooth muscle dedifferentiation genes., PMID:40266881
Melatonin-Stimulated Mesenchymal Stem Cells-Derived Exosomes Carrying LINC00052 Alleviate Hyperoxic Lung Injury by Promoting miR-152-3p-KLF4-Nrf2 Pathway., PMID:40258169
Pathogenic Variants and Prognosis in Meningiomas: A Systematic Review and Meta-Analysis., PMID:40254182
Perinuclear mitochondrial clustering for mesenchymal-to-epithelial transition in pluripotency induction., PMID:40250438
SIRT3 Represses Vascular Remodeling via Reducing Mitochondrial Ac-CoA Accumulation in Vascular Smooth Muscle Cells., PMID:40242869
Prognostic Value of <em>SOX9</em>, <em>E-Cadherin</em>, and <em>KLF4</em> Expressions in Clear Cell Renal Carcinoma., PMID:40235245
Generation of the induced pluripotent stem cell line LEIi023-A from a rod-cone dystrophy patient carrying the dominant PRPF31 c.267del variant., PMID:40220513
A secreted helminth microRNA suppresses gastrointestinal cell differentiation required for innate immunity., PMID:40213548
MiR-7a-Klf4 axis as a regulator and therapeutic target of neuroinflammation and ferroptosis in Alzheimer's disease., PMID:40196619
Heterogeneous condensates of transcription factors in embryonic stem cells: Molecular simulations., PMID:40195119
Bufalin inhibits immune escape in metastatic colorectal cancer by regulating M2 macrophage polarization., PMID:40186793
TRAF7 knockdown induces cellular senescence and synergizes with lomustine to inhibit glioma progression and recurrence., PMID:40181456
Glomerular mesangial cells derived complement factor H regulates complement activation, influences cell proliferation, and maintains actin cytoskeleton., PMID:40157080
DNA methylation memory of pancreatic acinar-ductal metaplasia transition state altering Kras-downstream PI3K and Rho GTPase signaling in the absence of Kras mutation., PMID:40156071
A Krüppel-like factor establishes cellular heterogeneity during schistosome tegumental maintenance., PMID:40153400
Efficient Fabrication of Human Corneal Stromal Cell Spheroids and Promoting Cell Stemness Based on 3D-Printed Derived PDMS Microwell Platform., PMID:40149974
Identification of a new micropeptide altKLF4 derived from KLF4 that influences myeloma chemotherapeutic sensitivity., PMID:40147548
For research use only. Not for human or drug use.
