Research Grade Meplazumab (DHE14001)

Catalog No.

DHE14001

Expression system

Mammalian Cells

Species reactivity

Human

Host species

Humanized

Isotype

IgG1-kappaorIGG2

Clonality

Monoclonal

Target

Hepatoma-associated antigen, BSG, HAb18G, 5F7, TCSF, OK blood group antigen, Collagenase stimulatory factor, CD147, Leukocyte activation antigen M6, Basigin, Extracellular matrix metalloproteinase inducer, EMMPRIN, Tumor cell-derived collagenase stimulatory factor

Concentration

1.8 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P35613

Applications

Research Grade Biosimilar

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

Meplazumab

Possible treatment and strategies for COVID-19: review and assessment, PMID: 33336780

FDA approved drugs with pharmacotherapeutic potential for SARS-CoV-2 (COVID-19) therapy, PMID: 32717568

Nonclinical safety, tolerance and pharmacodynamics evaluation for meplazumab treating chloroquine-resistant Plasmodium falciparum, PMID: 33088688

CD147-spike protein is a novel route for SARS-CoV-2 infection to host cells, PMID: 33277466

Tumor markers as an entry for SARS-CoV-2 infection?, PMID: 32738184

Safety and efficacy of meplazumab in healthy volunteers and COVID-19 patients: a randomized phase 1 and an exploratory phase 2 trial, PMID: 34001849

CD147 as an alternative binding site for the spike protein on the surface of SARS-CoV-2, PMID: 33336782

Document Download

Research Grade Meplazumab.pdf