Catalog No.
YHA60801
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Leu35-Asn276
Predicted molecular weight
28.95 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O43240
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
KLK10, Normal epithelial cell-specific 1, Protease serine-like 1, PRSSL1, NES1, Kallikrein-10
[Association between KLK10 gene methylation in female breast tumor tissue and the risk of invasive breast cancer]., PMID:40399130
SCGB3A1-Epi and KLK10-Epi Crosstalk With Fibroblasts Promotes Liver Metastasis of Breast Cancer and Pancreatic Ductal Adenocarcinoma., PMID:40357856
FGFBP1 promotes triple-negative breast cancer progression through the KLK10-AKT axis., PMID:40233428
KLK7 Involvement in Thyroid Papillary Carcinoma Cell Migration and Invasion by EMT via MAPK/ERK Pathways., PMID:39991575
Immunogenetic Studies in Patients With GAD-Positive Stiff-Person Syndrome Reveal Novel Lymphocytic Genes and KLK10-Gene Variants., PMID:39933127
Shear stress is uncoupled from atheroprotective KLK10 in atherosclerotic plaques., PMID:39413592
MicroRNA-141-regulated KLK10 and TNFSF-15 gene expression in hepatoblastoma cells as a novel mechanism in liver carcinogenesis., PMID:38866875
Glycolic acid-induced disruption of epidermal homeostasis in a skin equivalent model: Insights into temporal dynamics and mechanisms., PMID:38710400
LRG1 promotes the apoptosis of pulmonary microvascular endothelial cells through KLK10 in chronic obstructive pulmonary disease., PMID:38707515
KLK10 derived from tumor endothelial cells accelerates colon cancer cell proliferation and hematogenous liver metastasis formation., PMID:38475666
KLK7, KLK10, and KLK11 in Papillary Thyroid Cancer: Bioinformatic Analysis and Experimental Validation., PMID:38316654
KLK10 promotes the progression of KRAS mutant colorectal cancer via PAR1-PDK1-AKT signaling pathway., PMID:38115179
Kallikrein-related peptidase 10 predicts prognosis and mediates tumor immunomodulation in colorectal cancer., PMID:37972446
Identification and validation of key genes associated with pathogenesis and prognosis of gastric cancer., PMID:37868053
Comprehensive analyses of circulating cardiometabolic proteins and objective measures of fat mass., PMID:37550405
Role of cathepsin D induced by Porphyromonas gingivalis lipopolysaccharide in periodontitis., PMID:36788303
Targeted and explorative profiling of kallikrein proteases and global proteome biology of pancreatic ductal adenocarcinoma, chronic pancreatitis, and normal pancreas highlights disease-specific proteome remodelling., PMID:36610378
Kallikrein-Related Peptidase 6 (KLK6) as a Contributor toward an Aggressive Cancer Cell Phenotype: A Potential Role in Colon Cancer Peritoneal Metastasis., PMID:35883559
miR-194-3p represses the docetaxel resistance in colon cancer by targeting KLK10., PMID:35691099
Prospective quantitative gene expression analysis of kallikrein-related peptidase KLK10 as a diagnostic biomarker for childhood acute lymphoblastic leukemia., PMID:35669967
Stable flow-induced expression of KLK10 inhibits endothelial inflammation and atherosclerosis., PMID:35014606
MiR-194-3p modulates the progression of colorectal cancer by targeting KLK10., PMID:34935123
Identification and verification of key cancer genes associated with prognosis of colorectal cancer based on bioinformatics analysis., PMID:34911835
Kallikrein-Related Peptidase 6 Is Associated with the Tumour Microenvironment of Pancreatic Ductal Adenocarcinoma., PMID:34439122
The Role of Kallikrein10 (KLK10) Polymorphism in Prostate Cancer Susceptibility., PMID:34089177
Molecular Pathways Associated with Kallikrein 6 Overexpression in Colorectal Cancer., PMID:34065672
Identification of differentially expressed genes and signaling pathways in papillary thyroid cancer: a study based on integrated microarray and bioinformatics analysis., PMID:33708546
Use tumor suppressor genes as biomarkers for diagnosis of non-small cell lung cancer., PMID:33580150
Estrogen receptor-α prevents right ventricular diastolic dysfunction and fibrosis in female rats., PMID:33064565
Transcriptional Suppression of miR-7 by MTA2 Induces Sp1-Mediated KLK10 Expression and Metastasis of Cervical Cancer., PMID:32402941
Kallikrein-related peptidase (KLK10) cessation blunts colorectal cancer cell growth and glucose metabolism by regulating the PI3K/Akt/mTOR pathway., PMID:32386481
Gene Expression of Kallikreins in Breast Cancer Cell Lines., PMID:32366393
Molecular profiling for acromegaly treatment: a validation study., PMID:32302973
Kallikrein-related peptidases protein expression in lymphoid tissues suggests potential implications in immune response., PMID:31904348
Kallikrein-related peptidases 6 and 10 are elevated in cerebrospinal fluid of patients with Alzheimer's disease and associated with CSF-TAU and FDG-PET., PMID:31467673
NES1/KLK10 and hNIS gene therapy enhanced iodine-131 internal radiation in PC3 proliferation inhibition., PMID:31119602
Lamin A/C and Emerin depletion impacts chromatin organization and dynamics in the interphase nucleus., PMID:31117946
Circulating cell-free DNA in breast cancer: size profiling, levels, and methylation patterns lead to prognostic and predictive classifiers., PMID:30643192
Gene expression profiling identifies potential molecular markers of papillary thyroid carcinoma., PMID:30614796
MicroRNA-8073: Tumor suppressor and potential therapeutic treatment., PMID:30589909
A High-throughput Bead-based Affinity Assay Enables Analysis of Genital Protein Signatures in Women At Risk of HIV Infection., PMID:30504243
Elevated tumor tissue protein expression levels of kallikrein-related peptidases KLK10 and KLK11 are associated with a better prognosis in advanced high-grade serous ovarian cancer patients., PMID:30323977
Toll-like receptor signaling induces the expression of lympho-epithelial Kazal-type inhibitor in epidermal keratinocytes., PMID:30270115
Functional interrelationships between the kallikrein-related peptidases family and the classical kinin system in the human neutrophil., PMID:29883315
MiR-199b-5p promotes tumor growth and metastasis in cervical cancer by down-regulating KLK10., PMID:29807015
KLK10 exon 3 unmethylated PCR product concentration: a new potential early diagnostic marker in ovarian cancer? - A pilot study., PMID:29690914
Aberrant upregulation of KLK10 promotes metastasis via enhancement of EMT and FAK/SRC/ERK axis in PDAC., PMID:29621546
Kallikrein-related peptidases in lung diseases., PMID:29604204
NES1/KLK10 promotes trastuzumab resistance via activation of PI3K/AKT signaling pathway in gastric cancer., PMID:29231994
Clinical relevance of kallikrein-related peptidase 9, 10, 11, and 15 mRNA expression in advanced high-grade serous ovarian cancer., PMID:29095848
For research use only. Not for human or drug use.
