Research Grade Tisotumab (DHD00601)

Catalog No.

DHD00601

Expression system

Mammalian Cells

Species reactivity

Human

Host species

Human

Isotype

IgG1-kappa

Clonality

Monoclonal

Target

Tissue factor, CD142, F3, Thromboplastin, Coagulation factor III, TF

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P13726

Applications

Research Grade Biosimilar

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Alternative Names

HuMax-TF-ADC, TF-011-MMAE, HuMax-TF, CAS: 1418628-81-5

Clone ID

Tisotumab

Tisotumab Vedotin in Previously Treated Recurrent or Metastatic Cervical Cancer, PMID: 31796521

Tisotumab vedotin in patients with advanced or metastatic solid tumours (InnovaTV 201): a first-in-human, multicentre, phase 1-2 trial, PMID: 30745090

Tisotumab Vedotin Yields Responses as Second-Line Cervical Cancer Therapy, PMID: 33931438

Efficacy and safety of tisotumab vedotin in previously treated recurrent or metastatic cervical cancer (innovaTV 204/GOG-3023/ENGOT-cx6): a multicentre, open-label, single-arm, phase 2 study, PMID: 33845034

Treating Tissue Factor-Positive Cancers with Antibody-Drug Conjugates That Do Not Affect Blood Clotting, PMID: 30126944

Document Download

Research Grade Tisotumab.pdf