Catalog No.
YHA51601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Leu21-Gln297
Predicted molecular weight
57.74 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O15394
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
NCAM-2, N-CAM-2, NCAM21, NCAM2, Neural cell adhesion molecule 2
Changes in the Immune Profile and Chromatin Accessibility of Peripheral Regulatory T Cells in Psoriasis Patients Before and After Treatment With Biologics., PMID:40269508
Molecular Signatures of Resilience to Alzheimer's Disease in Neocortical Layer 4 Neurons., PMID:39574639
Machine learning model base on metabolomics and proteomics to predict cognitive impairment in Parkinson's disease., PMID:39394257
TAZ downregulated ANXA1 expression to modulate myeloma cell interactions with bone marrow mesenchymal stromal cells., PMID:39032857
Investigation of genetic determinants of cognitive change in later life., PMID:38238328
Regulation of young-adult neurogenesis and neuronal differentiation by neural cell adhesion molecule 2 (NCAM2)., PMID:37724425
Deficiency in the neural cell adhesion molecule 2 (NCAM2) reduces axonal levels of beta-site amyloid precursor protein cleaving enzyme 1 (BACE1), affects axonal organization in the hippocampus, and leads to behavioral deficits., PMID:37522285
Axonal mRNA binding of hnRNP A/B is crucial for axon targeting and maturation of olfactory sensory neurons., PMID:37083330
Hsa_circITGA4/ miR-1468/EGFR/ PTEN a Master Regulators Axis in Glioblastoma Development and Progression., PMID:37031335
Repeated administration of acrylamide for 28 days suppresses adult neurogenesis of the olfactory bulb in young-adult rats., PMID:36801352
Repeated administration of acrylamide for 28 days reduces late-stage progenitor cells and immature granule cells accompanying impaired neurite outgrowth in the adult hippocampal neurogenesis in young-adult rats., PMID:36328537
Cell adhesion proteins in the cerebrospinal fluid of neonates prenatally exposed to Zika virus: A case-control study., PMID:36300719
The BACE1-generated C-terminal fragment of the neural cell adhesion molecule 2 (NCAM2) promotes BACE1 targeting to Rab11-positive endosomes., PMID:36251052
ARID2 suppression promotes tumor progression and upregulates cytokeratin 8, 18 and β-4 integrin expression in TP53-mutated tobacco-related oral cancer and has prognostic implications., PMID:35869277
circ-Ncam2 (mmu_circ_0006413) Participates in LPS-Induced Microglia Activation and Neuronal Apoptosis via the TLR4/NF-κB Pathway., PMID:35687299
Identification of Novel Cerebrospinal Fluid Biomarkers for Cognitive Decline in Aneurysmal Subarachnoid Hemorrhage: A Proteomic Approach., PMID:35602555
Population Genomic Sequencing Delineates Global Landscape of Copy Number Variations that Drive Domestication and Breed Formation of in Chicken., PMID:35391799
The Hidden Side of NCAM Family: NCAM2, a Key Cytoskeleton Organization Molecule Regulating Multiple Neural Functions., PMID:34576185
New Partners Identified by Mass Spectrometry Assay Reveal Functions of NCAM2 in Neural Cytoskeleton Organization., PMID:34299022
The molecular underpinning of geminin-overexpressing triple-negative breast cancer cells homing specifically to lungs., PMID:33723406
Guide Cells Support Muscle Regeneration and Affect Neuro-Muscular Junction Organization., PMID:33669272
A Fucoxanthinol Induces Apoptosis in a Pancreatic Intraepithelial Neoplasia Cell., PMID:33608310
Spatiotemporal processing of neural cell adhesion molecules 1 and 2 by BACE1 in vivo., PMID:33548223
A molecular marker of milk composition traits in NCAM2 gene of Chinese Holstein., PMID:33314987
Using the Allen gene expression atlas of the adult mouse brain to gain further insight into the physiological significance of TAG-1/Contactin-2., PMID:32601750
NCAM2 Regulates Dendritic and Axonal Differentiation through the Cytoskeletal Proteins MAP2 and 14-3-3., PMID:32043120
Spatial Determination of Neuronal Diversification in the Olfactory Epithelium., PMID:30530861
NCAM2 Fibronectin type-III domains form a rigid structure that binds and activates the Fibroblast Growth Factor Receptor., PMID:29895898
Neural Cell Adhesion Molecule 2 (NCAM2)-Induced c-Src-Dependent Propagation of Submembrane Ca2+ Spikes Along Dendrites Inhibits Synapse Maturation., PMID:29522129
Systematic Functional Characterization of Human 21st Chromosome Orthologs in Caenorhabditis elegans., PMID:29367452
Gene CG15630 (fipi) is involved in regulation of the interpulse interval in Drosophila courtship song., PMID:29191114
Cell type-dependent axonal localization of translational regulators and mRNA in mouse peripheral olfactory neurons., PMID:28266018
Alterations of androgen receptor-regulated enhancer RNAs (eRNAs) contribute to enzalutamide resistance in castration-resistant prostate cancer., PMID:27221037
NCAM2 deletion in a boy with macrocephaly and autism: Cause, association or predisposition?, PMID:27596683
Diagnosis of Van den Ende-Gupta syndrome: Approach to the Marden-Walker-like spectrum of disorders., PMID:27375131
Aβ-dependent reduction of NCAM2-mediated synaptic adhesion contributes to synapse loss in Alzheimer's disease., PMID:26611261
The Stimulus-Dependent Gradient of Cyp26B1+ Olfactory Sensory Neurons Is Necessary for the Functional Integrity of the Olfactory Sensory Map., PMID:26446231
OCAM regulates embryonic spinal cord stem cell proliferation by modulating ErbB2 receptor., PMID:25875008
mRNA profiling reveals determinants of trastuzumab efficiency in HER2-positive breast cancer., PMID:25710561
Neural cell adhesion molecule 2 promotes the formation of filopodia and neurite branching by inducing submembrane increases in Ca2+ levels., PMID:25632147
21q21 deletion involving NCAM2: report of 3 cases with neurodevelopmental disorders., PMID:25464110
Identifying rare variants for genetic risk through a combined pedigree and phenotype approach: application to suicide and asthma., PMID:25335167
5' isomiR variation is of functional and evolutionary importance., PMID:25056318
Comparison of gene and protein expressions in rats residing in standard cages with those having access to an exercise wheel., PMID:24719897
Olfactory receptor and neural pathway responsible for highly selective sensing of musk odors., PMID:24361078
Human skin-derived stem cells as a novel cell source for in vitro hepatotoxicity screening of pharmaceuticals., PMID:23952781
The polysialyltransferases interact with sequences in two domains of the neural cell adhesion molecule to allow its polysialylation., PMID:23341449
A novel method for the simultaneous enrichment, identification, and quantification of phosphopeptides and sialylated glycopeptides applied to a temporal profile of mouse brain development., PMID:22843994
Neurons expressing trace amine-associated receptors project to discrete glomeruli and constitute an olfactory subsystem., PMID:22837392
Synaptic cell adhesion molecule-2 and collapsin response mediator protein-2 are novel members of the matrix metalloproteinase-9 degradome., PMID:22694054
For research use only. Not for human or drug use.
