Catalog No.
YHA43601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Trp318
Predicted molecular weight
37.36 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O15162
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Mg(2+)-dependent nuclease, Erythrocyte phospholipid scramblase, PLSCR1, PL scramblase 1, Phospholipid scramblase 1, MmTRA1b, Ca(2+)-dependent phospholipid scramblase 1
FOXA1 Transcriptional Repression of PLSCR1 Inhibits Tongue Squamous Cell Carcinoma Progression., PMID:40445264
Phospholipid scramblase 1: a frontline defense against viral infections., PMID:40248364
Identification of the molecular subtype and prognostic characteristics of lung adenocarcinoma based on CD8+ T cell-related gene signature., PMID:40095496
zDHHC-Mediated S-Palmitoylation in Skin Health and Its Targeting as a Treatment Perspective., PMID:40004137
Comparative RNA-Seq analysis of differentially expressed genes in the sertoli cells of yak and cattle-yak., PMID:39987073
PLSCR1 suppresses SARS-CoV-2 infection by downregulating cell surface ACE2., PMID:39945535
Protective effects of olive oil antioxidant phenols on mercury-induced phosphatidylserine externalization in erythrocyte membrane: Insights into scramblase and flippase activity., PMID:39613047
Phospholipid Scramblase 1 (PLSCR1) Regulates Interferon-Lambda Receptor 1 (IFN-λR1) and IFN-λ Signaling in Influenza A Virus (IAV) Infection., PMID:39605457
A genome-wide arrayed CRISPR screen identifies PLSCR1 as an intrinsic barrier to SARS-CoV-2 entry that recent virus variants have evolved to resist., PMID:39316623
Transcriptome analysis unveils PLSCR1 associated with microglial polarization in neuropathic pain., PMID:39312982
Deciphering the molecular nexus between Omicron infection and acute kidney injury: a bioinformatics approach., PMID:39027131
Phospholipid Scramblase 1 Localizes Proximal to Sphingomyelin Synthase Isoforms but Is Not Involved in Sphingomyelin Synthesis., PMID:38866522
Phospholipid Scramblase 1 Controls Efficient Neurotransmission and Synaptic Vesicle Retrieval at Cerebellar Synapses., PMID:38839301
The antiviral state of the cell: lessons from SARS-CoV-2., PMID:38795501
Phospholipid scramblase 1 acts through the IL-6/JAK/STAT3 pathway to promote the malignant progression of glioma., PMID:38636689
Machine learning framework develops neutrophil extracellular traps model for clinical outcome and immunotherapy response in lung adenocarcinoma., PMID:38519636
A Proteomic Investigation to Discover Candidate Proteins Involved in Novel Mechanisms of 5-Fluorouracil Resistance in Colorectal Cancer., PMID:38391955
Dysregulation of the circRNA_0087207/miR-548c-3p/PLSR1-TGFB2 axis in Leber hereditary optic neuropathy in vitro., PMID:38305450
Phospholipid scramblase 1 is involved in immunogenic cell death and contributes to dendritic cell-based vaccine efficiency to elicit antitumor immune response in vitro., PMID:38099895
An atlas of immune cell transcriptomes in human immunodeficiency virus-infected immunological non-responders identified marker genes that control viral replication., PMID:37914674
Fortifying immunity: PLSCR1 picks battle against SARS-CoV-2., PMID:37708846
PLSCR1 is a cell-autonomous defence factor against SARS-CoV-2 infection., PMID:37438530
Phospholipid scramblase-1 regulates innate type 2 inflammation in mouse lungs via CRTH2-dependent mechanisms., PMID:37289545
Quantitative proteomics of differentiated primary bronchial epithelial cells from chronic obstructive pulmonary disease and control identifies potential novel host factors post-influenza A virus infection., PMID:36713229
Pathogenesis of Human Immunodeficiency Virus and Mycobacterium tuberculosis Infection as Revealed by Transcriptome and Interactome Data., PMID:36648422
Identification of a novel recurrent EEF2 gene amplification in familial prostate tumors., PMID:36520140
Identification of immune-associated prognostic biomarkers in lung adenocarcinoma on the basis of gene co-expression network., PMID:36351297
The protective effects of curcumin on depression: Genes, transcription factors, and microRNAs involved., PMID:36162691
Phospholipid Scramblase 4 (PLSCR4) Regulates Adipocyte Differentiation via PIP3-Mediated AKT Activation., PMID:36077184
Identification of Critical Genes and Pathways for Influenza A Virus Infections via Bioinformatics Analysis., PMID:35893690
Phospholipid scramblase 1: a protein with multiple functions via multiple molecular interactors., PMID:35650588
ILDR1 promotes influenza A virus replication through binding to PLSCR1., PMID:35595813
Potential Small Molecules for Therapy of Lupus Nephritis Based on Genetic Effect and Immune Infiltration., PMID:35502341
Interaction of human phospholipid scramblase 1 with cholesterol via CRAC motif is essential for functional regulation and subcellular localization., PMID:35439477
Development and Validation of Ischemic Events Related Signature After Carotid Endarterectomy., PMID:35372347
Whole-genome sequencing reveals host factors underlying critical COVID-19., PMID:35255492
The Interferon-Inducible Human PLSCR1 Protein Is a Restriction Factor of Human Cytomegalovirus., PMID:35138119
Nuclear accumulation of KPNA2 impacts radioresistance through positive regulation of the PLSCR1-STAT1 loop in lung adenocarcinoma., PMID:34773335
Multi-Omics Analysis of Glioblastoma Cells' Sensitivity to Oncolytic Viruses., PMID:34771433
The ratio of ATP11C/PLSCR1 mRNA transcripts has clinical significance in sickle cell anemia., PMID:34651249
The diverse metabolic heterogeneity of stem cells in a BRCA+/-breast cancer population., PMID:34377198
Expression characteristics of interferon-stimulated genes and possible regulatory mechanisms in lupus patients using transcriptomics analyses., PMID:34284174
Identification and characterisation of a phospholipid scramblase in the malaria parasite Plasmodium falciparum., PMID:33974939
Shedding more light on the role of Midkine in hepatocellular carcinoma: New perspectives on diagnosis and therapy., PMID:33625758
Prognostic and Predictive Value of a 15 Transcription Factors (TFs) Panel for Hepatocellular Carcinoma., PMID:33293862
Single-Cell Transcriptome Analysis Highlights a Role for Neutrophils and Inflammatory Macrophages in the Pathogenesis of Severe COVID-19., PMID:33138195
RNA interference-mediated downregulation of phospholipid scramblase 1 expression in primary liver cancer in vitro., PMID:33133261
Reduction in flippase activity contributes to surface presentation of phosphatidylserine in human senescent erythrocytes., PMID:33103382
Heterogeneous ozone effects on the DNA methylome of bronchial cells observed in a crossover study., PMID:32978449
Study on the differentially expressed genes and signaling pathways in dermatomyositis using integrated bioinformatics method., PMID:32846838
For research use only. Not for human or drug use.
