Catalog No.
YHA42901
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Arg300
Predicted molecular weight
36.64 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O15144
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
ARC34, ARPC2, Arp2/3 complex 34 kDa subunit, p34-ARC, Actin-related protein 2/3 complex subunit 2
Inhibiting effect of LIPUS on epithelial-mesenchymal transition in lens epithelial cells., PMID:40449868
Overexpressed Palladin Rescues Enteropathogenic E. coli (EPEC) Pedestal Lengths in ArpC2 Depleted Cells., PMID:39692253
Enhanced Migration of Fuchs Corneal Endothelial Cells by Rho Kinase Inhibition: A Novel Ex Vivo Descemet's Stripping Only Model., PMID:39056800
Novel ApeC-containing protein mediates the recognition and internalization of Vibrio splendidus in Apostichopus japonicus., PMID:38986992
Fbxo28 is essential for spindle migration and morphology during mouse oocyte meiosis I., PMID:38960234
DEHP (di(2-ethylhexyl)phthalate) stimulates skin pigmentation by perturbing cytoskeletal homeostasis., PMID:38911535
Pharmacological modulation of developmental and synaptic phenotypes in human SHANK3 deficient stem cell-derived neuronal models., PMID:38858349
Actin Cytoskeleton Remodeling Accompanied by Redistribution of Adhesion Proteins Drives Migration of Cells in Different EMT States., PMID:38727316
Unearthing a novel function of SRSF1 in binding and unfolding of RNA G-quadruplexes., PMID:38567732
Arpc2 integrates ecdysone and juvenile hormone metabolism to influence metamorphosis and reproduction in Tribolium castaneum., PMID:38477435
Modified Danzhi Xiaoyao Powder (MDXP) improves the corneal damage in dry eye disease (DED) mice through phagocytosis., PMID:38070838
Unearthing SRSF1's Novel Function in Binding and Unfolding of RNA G-Quadruplexes., PMID:37961538
Actin polymerization inhibition by targeting ARPC2 affects intestinal stem cell homeostasis., PMID:37849945
Intelectin enhances the phagocytosis of macrophages via CDC42-WASF2-ARPC2 signaling axis in Megalobrama amblycephala., PMID:36907302
Steps of actin filament branch formation by Arp2/3 complex investigated with coarse-grained molecular dynamics., PMID:36733458
Genomic instability caused by Arp2/3 complex inactivation results in micronucleus biogenesis and cellular senescence., PMID:36706133
Gibberellic acid sensitive dwarf encodes an ARPC2 subunit that mediates gibberellic acid biosynthesis, effects to grain yield in rice., PMID:36618614
S-Benproperine, an Active Stereoisomer of Benproperine, Suppresses Cancer Migration and Tumor Metastasis by Targeting ARPC2., PMID:36558913
Inhibition of Arp2/3 Complex after ADP-Ribosylation of Arp2 by Binary Clostridioides Toxins., PMID:36429089
Quantitative proteomics identified circulating biomarkers in lung adenocarcinoma diagnosis., PMID:36404333
Novel insights into mouse models of ectopic proplatelet release., PMID:36251748
Proteomic characteristics of plasma and blood cells in natural aging rhesus monkeys., PMID:36037246
ARPC2: A Pan-Cancer Prognostic and Immunological Biomarker That Promotes Hepatocellular Carcinoma Cell Proliferation and Invasion., PMID:35733852
An investigation of mechanisms underlying mouse blastocyst hatching: a ribonucleic acid sequencing study., PMID:35559994
Actin-related protein 2/3 complex subunit 2-enriched extracellular vesicles drive liver cancer metastasis., PMID:35556226
Modification of BRCA1-associated breast cancer risk by HMMR overexpression., PMID:35393420
TNFRSF11B Suppresses Memory CD4+ T Cell Infiltration in the Colon Cancer Microenvironment: A Multiomics Integrative Analysis., PMID:34938284
The disease-associated proteins Drosophila Nab2 and Ataxin-2 interact with shared RNAs and coregulate neuronal morphology., PMID:34791182
Inhibition of the Arp2/3 complex represses human lung myofibroblast differentiation and attenuates bleomycin-induced pulmonary fibrosis., PMID:34453744
Identification of Arp2/3 Complex Subunits as Prognostic Biomarkers for Hepatocellular Carcinoma., PMID:34307456
Gene expression signatures differentiating major depressive disorder from subsyndromal symptomatic depression., PMID:33971621
Identification of Key Genes for Hepatitis Delta Virus-Related Hepatocellular Carcinoma by Bioinformatics Analysis., PMID:33960941
BLOC1S1/GCN5L1/BORCS1 is a critical mediator for the initiation of autolysosomal tubulation., PMID:33629936
The Actin Cytoskeleton Mediates Transmission of "Candidatus Liberibacter solanacearum" by the Carrot Psyllid., PMID:33188004
Alleviation of Lipopolysaccharide-Induced Acute Respiratory Distress Syndrome in Rats by Yiqi Huayu Jiedu Decoction: A Tandem Mass Tag-Based Proteomics Study., PMID:32982719
CB1-receptor-mediated inhibitory LTD triggers presynaptic remodeling via protein synthesis and ubiquitination., PMID:32902378
Altered Phosphorylation of Cytoskeleton Proteins in Peripheral Blood Mononuclear Cells Characterizes Chronic Antibody-Mediated Rejection in Kidney Transplantation., PMID:32899575
TRIM62 From Chicken as a Negative Regulator of Reticuloendotheliosis Virus Replication., PMID:32318585
Validation of Novel Prognostic Biomarkers for Early-Stage Clear-Cell, Endometrioid and Mucinous Ovarian Carcinomas Using Immunohistochemistry., PMID:32133296
Arp2/3 inactivation causes intervertebral disc and cartilage degeneration with dysregulated TonEBP-mediated osmoadaptation., PMID:31961823
Pimozide suppresses cancer cell migration and tumor metastasis through binding to ARPC2, a subunit of the Arp2/3 complex., PMID:31571309
Alternatively spliced variants of the 5'-UTR of the ARPC2 mRNA regulate translation by an internal ribosome entry site (IRES) harboring a guanine-quadruplex motif., PMID:31387452
ARPC2 promotes breast cancer proliferation and metastasis., PMID:31002363
RBM3 upregulates ARPC2 by binding the 3'UTR and contributes to breast cancer progression., PMID:30720048
Benproperine, an ARPC2 inhibitor, suppresses cancer cell migration and tumor metastasis., PMID:30710516
Proteomics of the Rat Myocardium during Development of Type 2 Diabetes Mellitus Reveals Progressive Alterations in Major Metabolic Pathways., PMID:29847139
Identification of genes related to consecutive trauma-induced sepsis via gene expression profiling analysis., PMID:29642183
Comprehensive identification of proteins binding to RNA G-quadruplex motifs in the 5' UTR of tumor-associated mRNAs., PMID:29129743
Arp2/3 Complex Is Required for Macrophage Integrin Functions but Is Dispensable for FcR Phagocytosis and In Vivo Motility., PMID:28867487
Arp2/3 complex controls T cell homeostasis by maintaining surface TCR levels via regulating TCR+ endosome trafficking., PMID:28827576
For research use only. Not for human or drug use.
