Catalog No.
YHA36801
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ile5-Lys290
Predicted molecular weight
33.42 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O14977
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
AZIN1, OAZIN, AZI1, Antizyme inhibitor 1, OAZI, AZI, Ornithine decarboxylase antizyme inhibitor
AZIN1-dependent polyamine synthesis accelerates tumor cell cycle progression and impairs effector T-cell function in osteosarcoma., PMID:40246846
Toxoplasma gondii macrophage migration inhibitory factor shows anti-Mycobacterium tuberculosis potential via AZIN1/STAT1 interaction., PMID:39453997
Inflammation primes the murine kidney for recovery by activating AZIN1 adenosine-to-inosine editing., PMID:38954486
RNA editing of AZIN1 coding sites is catalyzed by ADAR1 p150 after splicing., PMID:37209819
Long non-coding RNA MALAT1 aggravated liver ischemia-reperfusion injury via targeting miR-150-5p/AZIN1., PMID:36700468
AZIN1 RNA editing alters protein interactions, leading to nuclear translocation and worse outcomes in prostate cancer., PMID:36202978
ADAR1 and AZIN1 RNA editing function as an oncogene and contributes to immortalization in endometrial cancer., PMID:35697535
A novel mechanism for A-to-I RNA-edited AZIN1 in promoting tumor angiogenesis in colorectal cancer., PMID:35365616
A comprehensive RNA editome reveals that edited Azin1 partners with DDX1 to enable hematopoietic stem cell differentiation., PMID:34388251
Antizyme inhibitor 2 (AZIN2) associates with better prognosis of head and neck minor salivary gland adenoid cystic carcinoma., PMID:34046926
Targeting RNA editing of antizyme inhibitor 1: A potential oligonucleotide-based antisense therapy for cancer., PMID:33974998
Aberrant AZIN2 and polyamine metabolism precipitates tau neuropathology., PMID:33586680
The cell line A-to-I RNA editing catalogue., PMID:32383740
Identification of a novel structure-specific endonuclease AziN that contributes to the repair of azinomycin B-mediated DNA interstrand crosslinks., PMID:31713613
Developing a novel FRET assay, targeting the binding between Antizyme-AZIN., PMID:30874587
Ornithine decarboxylase antizyme inhibitor 2 (AZIN2) is a signature of secretory phenotype and independent predictor of adverse prognosis in colorectal cancer., PMID:30768610
Activation of AZIN1 RNA editing is a novel mechanism that promotes invasive potential of cancer-associated fibroblasts in colorectal cancer., PMID:30583079
New insights of polyamine metabolism in testicular physiology: A role of ornithine decarboxylase antizyme inhibitor 2 (AZIN2) in the modulation of testosterone levels and sperm motility., PMID:30566531
Enhanced AZIN1 RNA editing and overexpression of its regulatory enzyme ADAR1 are important prognostic biomarkers in gastric cancer., PMID:30563560
Control of the polyamine biosynthesis pathway by G2-quadruplexes., PMID:30063205
AZIN1 RNA editing confers cancer stemness and enhances oncogenic potential in colorectal cancer., PMID:29925690
Polyamine Control of Translation Elongation Regulates Start Site Selection on Antizyme Inhibitor mRNA via Ribosome Queuing., PMID:29677493
The mouse Gm853 gene encodes a novel enzyme: Leucine decarboxylase., PMID:29108956
RNA editing of AZIN1 induces the malignant progression of non-small-cell lung cancers., PMID:28849733
Antizyme inhibitor 1: a potential carcinogenic molecule., PMID:27870265
Structural basis of Ornithine Decarboxylase inactivation and accelerated degradation by polyamine sensor Antizyme1., PMID:26443277
Structural basis of antizyme-mediated regulation of polyamine homeostasis., PMID:26305948
RefSeq curation and annotation of antizyme and antizyme inhibitor genes in vertebrates., PMID:26170238
Control of Polyamine Biosynthesis by Antizyme Inhibitor 1 Is Important for Transcriptional Regulation of Arginine Vasopressin in the Male Rat Hypothalamus., PMID:25961839
A role for antizyme inhibitor in cell proliferation., PMID:25813938
Influence of ornithine decarboxylase antizymes and antizyme inhibitors on agmatine uptake by mammalian cells., PMID:25655388
Structural and degradative aspects of ornithine decarboxylase antizyme inhibitor 2., PMID:24967154
Adenosine-to-inosine RNA editing mediated by ADARs in esophageal squamous cell carcinoma., PMID:24302582
TGF-β-induced signaling circuit loops mediated by microRNAs as new therapeutic targets for renal fibrosis?, PMID:24280747
Inhibiting cycloxygenase and ornithine decarboxylase by diclofenac and alpha-difluoromethylornithine blocks cutaneous SCCs by targeting Akt-ERK axis., PMID:24260338
Multiple forms of mouse antizyme inhibitor 1 mRNA differentially regulated by polyamines., PMID:24077669
The microRNA miR-433 promotes renal fibrosis by amplifying the TGF-β/Smad3-Azin1 pathway., PMID:23868013
A candidate gene study for the association of host single nucleotide polymorphisms with liver cirrhosis risk in chinese hepatitis B patients., PMID:23844940
RNA editing enters the limelight in cancer., PMID:23389604
Recoding RNA editing of AZIN1 predisposes to hepatocellular carcinoma., PMID:23291631
Synthesis and characterization of a stimulus-responsive L-ornithine-degrading hydrogel., PMID:23142579
Expression and distribution of genes encoding for polyamine-metabolizing enzymes in the different zones of male and female mouse kidneys., PMID:22562773
Minimal antizyme peptide fully functioning in the binding and inhibition of ornithine decarboxylase and antizyme inhibitor., PMID:21931692
Knockdown of antizyme inhibitor decreases prostate tumor growth in vivo., PMID:21909979
A polymorphism that delays fibrosis in hepatitis C promotes alternative splicing of AZIN1, reducing fibrogenesis., PMID:21837750
Transcriptomic analysis of the osmotic and reproductive remodeling of the female rat supraoptic nucleus., PMID:21791562
[Polymorphism of ornithine decarboxylase antizyme inhibitor 1 gene is associated with liver cirrhosis in Chinese hepatitis B patients]., PMID:21586232
Identification, assay, and functional analysis of the antizyme inhibitor family., PMID:21318879
Antizyme restrains centrosome amplification by regulating the accumulation of Mps1 at centrosomes., PMID:20861309
Changes in liver gene expression of Azin1 knock-out mice., PMID:20737923
For research use only. Not for human or drug use.
