Catalog No.
YHA16801
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ser23-Leu428
Predicted molecular weight
43.92 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O00592
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
PCLP1, Podocalyxin-like protein 1, GCTM-2 antigen, Gp200, PODXL, Podocalyxin, PC, PCLP, PCLP-1
Stromal Cell-Derived Factor-1, P-Selectin, and Advanced Oxidation Protein Products with Mitochondrial Dysfunction Concurrently Impact Cerebral Vessels in Patients with Normoalbuminuric Diabetic Kidney Disease and Type 2 Diabetes Mellitus., PMID:40429625
Therapeutic Efficacy of Mesenchymal Stem Cells in Modulating Oxidative Stress in Puromycin-Induced Nephropathy., PMID:40407599
Whole genome sequencing identifies monogenic disease in 56.1% of families with early-onset steroid-resistant nephrotic syndrome., PMID:40402239
Renal Implications of Psoriasis: Urinary Podocyte Markers and Disease Progression., PMID:40401891
Asperosaponin VI Promotes Osteoporotic Fracture Healing by Targeting Piezo1 to Enhance the Coupling of LEPR+ BMSCs and PODXL+ ECs., PMID:40393465
Multi-omic features and clustering phenotypes of circulating tumor cells associated with metastasis and clinical outcomes., PMID:40287221
Novel Truncating Variants in PODXL Represent a New Entity to Be Explored Among Podocytopathies., PMID:40282423
Yishen Tongluo formula ameliorates kidney injury modulating inflammation and apoptosis in streptozotocin-induced diabetic kidney disease mice., PMID:40151112
Podocyte-Specific Protein Expression in Urine Exosome Acts as a Marker for Renal Injury in Post-COVID State., PMID:40100769
Development of chimeric antigen receptor T cells targeting cancer-expressing podocalyxin., PMID:39867135
Mechanism Study on the Regulation of Th1/Th2 in the Treatment of Idiopathic Membranous Nephropathy by Shengyang Yiwei Decoction., PMID:39812058
Anti-Adhesive Podocalyxin Expression Is Disrupted in Recurrent Implantation Failure., PMID:39795629
APOL1 Modulates Renin-Angiotensin System., PMID:39766282
Investigation of clinical and subclinical renal damage in Psoriasis., PMID:39666126
Development of a Multiplexed LC-MS/MS Assay for the Quantitation of Podocyte Injury Biomarkers Nephrin, Podocalyxin, and Podocin in Human Urine., PMID:39651829
Receptive window might be shorter in patients with endometriosis and lesions cyclically prepare for implantation., PMID:39643002
Isoferulic acid regulates CXCL12/CXCR4-mediated apoptosis and autophagy in podocyte and mice with STZ-induced diabetic nephropathy., PMID:39616856
Comparative proteomic exploration of plasma proteins in different levels of vitamin D with type 2 diabetes mellitus using iTRAQ-coupled LC-MS/MS., PMID:39610489
Towards the Identification of New Biomarkers in Saliva and Serum for Treatment Monitoring of Equine Gastric Ulcer Syndrome: A Liquid Proteomic Approach., PMID:39518828
Bidirectional signals generated by Siglec-7 and its crucial ligand tri-sialylated T to escape of cancer cells from immune surveillance., PMID:39507251
Dependence of PAX3-FOXO1 chromatin occupancy on ETS1 at important disease-promoting genes exposes new targetable vulnerability in Fusion-Positive Rhabdomyosarcoma., PMID:39448867
Polycystic Ovary Syndrome Accompanied by Hyperandrogenemia or Metabolic Syndrome Triggers Glomerular Podocyte Injury., PMID:39410601
Single-cell RNA transcriptomics reveals Du-Zhong-Wan promotes osteoporotic fracture healing via YAP/β-catenin/VEGF axis in BMSCs., PMID:39366157
Adriamycin-induced podocyte injury via the Sema3A/TRPC5/Rac1 pathway., PMID:39301490
Tumor endothelium-derived PODXL correlates with immunosuppressive microenvironment and poor prognosis in cervical cancer patients receiving radiotherapy or chemoradiotherapy., PMID:39294825
PPAR-α Insufficiency Enhances Doxorubicin-Induced Nephropathy in PPAR-α Knockout Mice and a Murine Podocyte Cell Line., PMID:39273018
Has_circ_0002360 promotes the progression of lung adenocarcinoma by activating miR-762 and regulating PODXL expression., PMID:39262484
PODXL promotes malignant progression of hepatocellular carcinoma by activating PI3K/AKT pathway., PMID:39198365
CRISPR Screening of Transcribed Super-Enhancers Identifies Drivers of Triple-Negative Breast Cancer Progression., PMID:39186674
Non-endothelial expression of endomucin in the mouse and human choroid., PMID:39153592
6-Gingerol modulates miRNAs and PODXL gene expression via methyltransferase enzymes in NB4 cells: an in silico and in vitro study., PMID:39112503
The Immunosuppressive Drug LF15-0195 Acts Also on Glomerular Lesions, by a Change in Cytoskeleton Distribution in Podocyte., PMID:39074452
Expression of Podocalyxin Potentially Decorated With Low-sulfated Keratan Sulfate in Human Testicular Embryonal Carcinoma., PMID:39051568
Evaluating new biomarkers for diabetic nephropathy: Role of α2-macroglobulin, podocalyxin, α-L-fucosidase, retinol-binding protein-4, and cystatin C., PMID:38983807
EGR3 reduces podocyte inflammatory damage in obesity related glomerulopathy by inhibiting the PRMT1/p-STAT3 pathway., PMID:38970508
Urine Nephrin and Podocalyxin Reflecting Podocyte Damage and Severity of Kidney Disease in Various Glomerular Diseases-A Cross-Sectional Study., PMID:38929959
Catechin-Induced changes in PODXL, DNMTs, and miRNA expression in Nalm6 cells: an integrated in silico and in vitro approach., PMID:38879474
Interferon-γ induces combined pyroptotic angiopathy and APOL1 expression in human kidney disease., PMID:38838223
Non-endothelial expression of Endomucin in the mouse and human choroid., PMID:38559191
Podocalyxin promotes the formation of compact and chemoresistant cancer spheroids in high grade serous carcinoma., PMID:38553472
Redistribution of the glycocalyx exposes phagocytic determinants on apoptotic cells., PMID:38359833
Urinary podocyte markers in diabetic kidney disease., PMID:38325865
Identification of specific markers for human pluripotent stem cell-derived small extracellular vesicles., PMID:38321535
A Cancer-Specific Monoclonal Antibody against Podocalyxin Exerted Antitumor Activities in Pancreatic Cancer Xenografts., PMID:38203331
Subcellular trafficking and transcytosis efficacy of different receptor types for therapeutic antibody delivery at the blood‒brain barrier., PMID:37932749
AT7867 promotes pancreatic progenitor differentiation of human iPSCs., PMID:37922913
Effects and mechanism of Rictor interference in podocyte injury induced by high glucose., PMID:37753299
Repurposing fexofenadine as a promising candidate for diabetic kidney disease: randomized clinical trial., PMID:37741921
Therapeutic potential of a novel peripherally restricted CB1R inverse agonist on the progression of diabetic nephropathy., PMID:37675364
Sirtuin 6 protects against podocyte injury by blocking the renin-angiotensin system by inhibiting the Wnt1/β-catenin pathway., PMID:37640899
For research use only. Not for human or drug use.
