Catalog No.
YHA12901
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Asp200-Met334
Predicted molecular weight
17.26 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O00470
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Homeobox protein Meis1, MEIS1
A locally aggressive pelvic MEIS1::NCOA1 fusion sarcoma in a young adult female: a case report and review of the literature., PMID:40420135
MEIS1: From functional versatility to post-transcriptional/translational regulation., PMID:40339957
MEIS1 knockdown upregulates WNT signaling pathway genes in esophageal squamous cell carcinoma., PMID:40211274
Inflammatory signaling pathways play a role in SYK inhibitor resistant AML., PMID:40188268
MEIS1::NCOA1 Primitive Spindle Cell Sarcoma of the Kidney : Report of 7 Cases of a Distinctive Clinicopathologic Entity., PMID:40160183
Pelvic spindle cell sarcomas harboring MEIS1::NCOA2 fusion and novel gene amplifications in 10q23-26 region: a potential predictor for tumor progression., PMID:40111447
Ubiquitous MEIS transcription factors actuate lineage-specific transcription to establish cell fate., PMID:40021842
Comparative analysis of the Mexico City Prospective Study and the UK Biobank identifies ancestry-specific effects on clonal hematopoiesis., PMID:39948438
MEIS1-mediated Apoptosis via TNFR1 in Endometriosis., PMID:39934615
Interaction Between Malat1 and miR-499-5p Regulates Meis1 Expression and Function with a Net Impact on Cell Proliferation., PMID:39851553
Integrated analysis of ATAC-seq and RNA-seq reveals the chromatin accessibility and transcriptional landscape of immunoglobulin a nephropathy., PMID:39848509
Oncogenic role of RARG rearrangements in acute myeloid leukemia resembling acute promyelocytic leukemia., PMID:39805831
MLL1 promotes placental trophoblast ferroptosis and aggravates preeclampsia symptoms through epigenetic regulation of RBM15/TRIM72/ADAM9 axis., PMID:39709463
Bleximenib, the novel menin-KMT2A inhibitor JNJ-75276617, impairs long-term proliferation and immune evasion in acute myeloid leukemia., PMID:39704147
Meis transcription factors regulate cardiac conduction system development and adult function., PMID:39691060
Integration of multi-omics layers empowers precision diagnosis through unveiling pathogenic mechanisms on maple syrup urine disease., PMID:39659154
TIFAB modulates metabolic pathways in KMT2A::MLLT3-induced AML through HNF4A., PMID:39626355
Targeting chromatin modifying complexes in acute myeloid leukemia., PMID:39607901
RLS-associated MEIS transcription factors control distinct processes in human neural stem cells., PMID:39578497
The regenerative effect of exosomes isolated from mouse embryonic fibroblasts in mice created as a sciatic nerve crush injury model., PMID:39388029
Epigenomic and Transcriptomic Profiling of Solitary Fibrous Tumors Identifies Site-Specific Patterns and Candidate Genes Regulated by DNA Methylation., PMID:39357799
Unraveling MLL1-fusion leukemia: Epigenetic revelations from an iPS cell point mutation., PMID:39342993
Identification of FDA-approved drugs that induce heart regeneration in mammals., PMID:39183959
Menin inhibitors in pediatric acute leukemia: a comprehensive review and recommendations to accelerate progress in collaboration with adult leukemia and the international community., PMID:39179671
Meis1 Targets Protein Tyrosine Phosphatase Receptor J in Fibroblast to Retard Chronic Kidney Disease Progression., PMID:39162106
Molecular basis of facilitated target search and sequence discrimination of TALE homeodomain transcription factor Meis1., PMID:39143123
The E3 ubiquitin ligase Herc1 modulates the response to nucleoside analogs in acute myeloid leukemia., PMID:39093953
Transcription factor Meis1b regulates craniofacial morphogenesis in zebrafish., PMID:39087648
Preclinical efficacy of the potent, selective menin-KMT2A inhibitor JNJ-75276617 (bleximenib) in KMT2A- and NPM1-altered leukemias., PMID:38905635
Disparity of gene expression in coronary artery disease: insights from MEIS1, HIRA, and Myocardin., PMID:38824221
A Comprehensive Analysis of HOXB13 Expression in Hepatocellular Carcinoma., PMID:38792899
Development of stemness-related signature to optimize prognosis prediction and identify XMD8-85 as a novel therapeutic compound for glioma., PMID:38768760
The Menin story in acute myeloid leukaemia-The road to success., PMID:38710595
Low-grade undifferentiated sarcoma with MEIS1::NCOA2-rearrangement primary to the lung: a case report., PMID:38678288
ERN1 knockdown modifies the hypoxic regulation of homeobox gene expression in U87MG glioblastoma cells., PMID:38563293
Potential drug targets for gastroesophageal reflux disease and Barrett's esophagus identified through Mendelian randomization analysis., PMID:38429412
MBNL1 Regulates Programmed Postnatal Switching Between Regenerative and Differentiated Cardiac States., PMID:38426339
Discovery of novel pyrrolo[2,3-d]pyrimidines as potent menin-mixed lineage leukemia interaction inhibitors., PMID:38367493
A patient-enriched MEIS1 coding variant causes a restless legs syndrome-like phenotype in mice., PMID:38314840
Therapeutic targeting in pediatric acute myeloid leukemia with aberrant HOX/MEIS1 expression., PMID:38174649
A mouse model of MEIS1-associated restless legs syndrome: insights and challenges., PMID:38150482
Methylation and transcriptomic expression profiles of HUVEC in the oxygen and glucose deprivation model and its clinical implications in AMI patients., PMID:38145212
Molecular mechanisms of pelvic organ prolapse influenced by FBLN5 via FOSL1/miR-222/MEIS1/COL3A1 axis., PMID:38056607
Transcriptional control of leukemogenesis by the chromatin reader SGF29., PMID:38048593
Discovery, Structure-Activity Relationship and In Vitro Anticancer Activity of Small-Molecule Inhibitors of the Protein-Protein Interactions between AF9/ENL and AF4 or DOT1L., PMID:37958457
MEIS inhibitors reduce the viability of primary leukemia cells and Stem cells by inducing apoptosis., PMID:37902585
Acute myeloid leukemias with UBTF tandem duplications are sensitive to menin inhibitors., PMID:37890156
Differential transcriptional control of hematopoiesis in congenital and cyclic neutropenia patients harboring ELANE mutations., PMID:37855057
The effect Of vascular related CeRNA genes and corresponding imaging biomarkers on survival in lower grade glioma., PMID:37801268
A methylation- and immune-related lncRNA signature to predict ovarian cancer outcome and uncover mechanisms of chemoresistance., PMID:37674251
For research use only. Not for human or drug use.
