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Recombinant Human AGRN Protein, N-His

Catalog #:   YHA12701 Specific References (49) DATASHEET
Applications: ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Expression system: E. coli
Accession: O00468
Protein length: Cys1856-Val2045
Overview

Catalog No.

YHA12701

Expression system

E. coli

Species

Homo sapiens (Human)

Protein length

Cys1856-Val2045

Predicted molecular weight

22.56 kDa

Nature

Recombinant

Endotoxin level

Please contact with the lab for this information.

Purity

>90% as determined by SDS-PAGE.

Accession

O00468

Applications

ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress

Form

Lyophilized

Storage buffer

Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.

Reconstitution

Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.

Shipping

In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Alternative Names

AGRN, C22, Agrin, C90, AGRIN

Data Image
  • SDS-PAGE
    SDS PAGE for recombinant Human AGRN protein
References

Cerebrospinal fluid protein biomarkers are associated with response to multiagent intraventricular chemotherapy in patients with CNS lymphoma., PMID:40321620

A model of basement membrane-related regulators for prediction of prognoses in esophageal cancer and verification in vitro., PMID:40234833

Agrin-deficient osteocytes disrupt bone tissue homeostasis in male mice., PMID:40158584

Identifying novel AGRN variants in congenital myasthenic syndrome: insights from three Iranian families., PMID:40157165

Cellular SLC35B4 promotes internalization during influenza A virus entry., PMID:40130891

Analysing glycolysis-related genes reveals the prognostic and diagnostic relevance of IER3 and AGRN in colorectal cancer., PMID:40048143

Acute high-intensity muscle contraction moderates AChR gene expression independent of rapamycin-sensitive mTORC1 pathway in rat skeletal muscle., PMID:39501426

Targeted Therapy of Osteoarthritis via Intra-Articular Delivery of Lipid-Nanoparticle-Encapsulated Recombinant Human FGF18 mRNA., PMID:39363784

Potential Plasma Proteins (LGALS9, LAMP3, PRSS8 and AGRN) as Predictors of Hospitalisation Risk in COVID-19 Patients., PMID:39334929

Local protein synthesis at neuromuscular synapses is required for motor functions., PMID:39178112

Copy number variation and clinical response to chemotherapy and bevacizumab in the Czech metastatic colorectal cancer patients., PMID:39174331

Identification of a basement membrane-related gene signature for predicting prognosis, immune infiltration, and drug sensitivity in colorectal cancer., PMID:39011483

Congenital myasthenic syndromes in adults: clinical features, diagnosis and long-term prognosis., PMID:38696726

Proteomic analysis of DEN and CCl4-induced hepatocellular carcinoma mouse model., PMID:38580754

Suppression of AGRN enhances CD8+ T cell recruitment and inhibits breast cancer progression., PMID:38568853

Mild hypothermia reduces lipopolysaccharide-induced microglial activation via down-regulation of Tent5c., PMID:38484570

Transcriptome Profiling Identifies Differentially Expressed Genes in Skeletal Muscle Development in Native Chinese Ducks., PMID:38254942

Identification and validation of plasma AGRN as a novel diagnostic biomarker of hepatitis B Virus-related chronic hepatitis and liver fibrosis/cirrhosis., PMID:38197199

Mimicked Spinal Cord Fibers Trigger Axonal Regeneration and Remyelination after Injury., PMID:38078771

The YAP1/TAZ-TEAD transcriptional network regulates gene expression at neuromuscular junctions in skeletal muscle fibers., PMID:38048326

Bioinformatics-based analysis of the roles of basement membrane-related gene AGRN in systemic lupus erythematosus and pan-cancer development., PMID:37841281

Agrin is a novel oncogenic protein in thyroid cancer., PMID:37818129

AGRN promotes lung adenocarcinoma progression by activating Notch signaling pathway and acts as a therapeutic target., PMID:37321467

Neural Isoforms of Agrin Are Generated by Reduced PTBP1-RNA Interaction Network Spanning the Neuron-Specific Splicing Regions in AGRN., PMID:37108583

Clinical and Pathologic Features of Congenital Myasthenic Syndromes Caused by 35 Genes-A Comprehensive Review., PMID:36835142

Urinary protein biomarkers based on LC-MS/MS analysis to discriminate vascular dementia from Alzheimer's disease in Han Chinese population., PMID:36761180

Matrine restrains the development of colorectal cancer through regulating the AGRN/Wnt/β-catenin pathway., PMID:36620879

Genes encoding agrin (AGRN) and neurotrypsin (PRSS12) are associated with muscle mass, strength and plasma C-terminal agrin fragment concentration., PMID:36609795

Diagnostic yield of a practical electrodiagnostic protocol discriminating between different congenital myasthenic syndromes., PMID:36522822

Cytoplasmic pool of U1 spliceosome protein SNRNP70 shapes the axonal transcriptome and regulates motor connectivity., PMID:36384140

A link between agrin signalling and Cav3.2 at the neuromuscular junction in spinal muscular atrophy., PMID:36347955

Unfolding of Novel Independent Missense Mutations in VAMP2 and AGRN and Their Collective Role in Global Developmental Delay: A Case Report., PMID:36176870

Congenital Myasthenic Syndromes in Turkey: Clinical and Molecular Characterization of 16 Cases With Three Novel Mutations., PMID:36099689

Severe congenital myasthenic syndromes caused by agrin mutations affecting secretion by motoneurons., PMID:35948834

A timeseries analysis of the fracture callus extracellular matrix proteome during bone fracture healing., PMID:35765657

Clinicopathological-genetic features of congenital myasthenic syndrome from a Chinese neuromuscular centre., PMID:35670010

Methylated DNA markers for plasma detection of ovarian cancer: Discovery, validation, and clinical feasibility., PMID:35370009

CRABP1-CaMKII-Agrn regulates the maintenance of neuromuscular junction in spinal motor neuron., PMID:35217789

SPINK5 is a Prognostic Biomarker Associated With the Progression and Prognosis of Laryngeal Squamous Cell Carcinoma Identified by Weighted Gene Co-Expression Network Analysis., PMID:35140453

Mutational screening of AGRN, SLC39A5, SCO2, P4HA2, BSG, ZNF644, and CPSF1 in a Chinese cohort of 103 patients with nonsyndromic high myopia., PMID:35002215

Agrin Loss in Barrett's Esophagus-Related Neoplasia and Its Utility as a Diagnostic and Predictive Biomarker., PMID:34785582

Novel LG1 Mutations in Agrin Causing Congenital Myasthenia Syndrome., PMID:34433720

Myasthenia gravis genome-wide association study implicates AGRN as a risk locus., PMID:34400559

Curcumin suppresses LGR5(+) colorectal cancer stem cells by inducing autophagy and via repressing TFAP2A-mediated ECM pathway., PMID:33713277

Molecular mechanisms of osteogenesis and antibacterial activity of Cu-bearing Ti alloy in a bone defect model with infection in vivo., PMID:33437640

Modulation of the Acetylcholine Receptor Clustering Pathway Improves Neuromuscular Junction Structure and Muscle Strength in a Mouse Model of Congenital Myasthenic Syndrome., PMID:33390901

Secretome Analysis of Inductive Signals for BM-MSC Transdifferentiation into Salivary Gland Progenitors., PMID:33260559

A Comprehensive Analysis of Unique and Recurrent Copy Number Variations in Alzheimer's Disease and its Related Disorders., PMID:33256577

Agrin promotes the proliferation, invasion and migration of rectal cancer cells via the WNT signaling pathway to contribute to rectal cancer progression., PMID:32862766

Datasheet
$ 313
Product specifications
100 μg 313 1 mg 1629

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For research use only. Not for human or drug use.

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Recombinant Human AGRN Protein, N-His [YHA12701]
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