Catalog No.
YHA10101
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ser37-Ala181
Predicted molecular weight
18.08 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O00391
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
QSOX1, Sulfhydryl oxidase 1, hQSOX, Quiescin Q6, QSCN6
Beyond Exosomes: An Ultrapurified Phospholipoproteic Complex (PLPC) as a Scalable Immunomodulatory Platform for Reprogramming Immune Suppression in Metastatic Cancer., PMID:40427155
(-)-Epigallocatechin-3-Gallate and Quercetin Inhibit Quiescin Sulfhydryl Oxidase 1 Secretion from Hepatocellular Carcinoma Cells., PMID:39857439
Identify and analyze ferroptosis-related molecular modules and immune signatures in epilepsy using microarray-based transcriptome profiling and single-cell sequencing., PMID:39848347
QSOX1 Modulates Glioblastoma Cell Proliferation and Migration In Vitro and Invasion In Vivo., PMID:39518060
QSOX1 facilitates dormant esophageal cancer stem cells to evade immune elimination via PD-L1 upregulation and CD8 T cell exclusion., PMID:39432781
A Comparison of White and Yellow Seminal Plasma Phosphoproteomes Obtained from Turkey (Meleagris gallopavo) Semen., PMID:39337428
QSOX1 exerts anti-inflammatory effects in sepsis-induced acute lung injury: Regulation involving EGFR phosphorylation mediated M1 polarization of macrophages., PMID:39251039
Systematic Proteome Profiling of Maternal Plasma for Development of Preeclampsia Biomarkers., PMID:39111712
Caveolae-mediated endocytosis of extracellular QSOX1b modulates the migration of fibroblasts., PMID:38176465
Proteomic profiling of human menisci from mild joint degeneration and end-stage osteoarthritis versus healthy controls., PMID:38098679
S-nitrosylation switches the Arabidopsis redox sensor protein, QSOX1, from an oxidoreductase to a molecular chaperone under heat stress., PMID:38048703
Development of tandem antigen capture ELISAs measuring QSOX1 isoforms in plasma and serum., PMID:38036070
Identification of Diagnosis and Typological Characteristics Associated with Ferroptosis for Ulcerative Colitis via Bioinformatics and Machine Learning., PMID:37957905
Computational optimization of antibody humanness and stability by systematic energy-based ranking., PMID:37550425
Aberrant m5C hypermethylation mediates intrinsic resistance to gefitinib through NSUN2/YBX1/QSOX1 axis in EGFR-mutant non-small-cell lung cancer., PMID:37161388
Effects of redox modulation on quiescin/sulfhydryl oxidase activity of melanoma cells., PMID:37103678
Study on the pathogenesis of MiR-6324 regulating diarrheal irritable bowel syndrome and bioinformatics analysis., PMID:36873998
Protein Identification of Seminal Plasma in Bali Bull (Bos javanicus)., PMID:36766403
Secretion of the disulfide bond generating catalyst QSOX1 from pancreatic tumor cells into the extracellular matrix: association with extracellular vesicles and matrix proteins., PMID:36590238
Genome-wide placental DNA methylations in fetal overgrowth and associations with leptin, adiponectin and fetal growth factors., PMID:36585686
A Golgi oxygen sensor controls intestinal mucin glycosylation., PMID:36382686
N6-methyladenosine-modified circular RNA QSOX1 promotes colorectal cancer resistance to anti-CTLA-4 therapy through induction of intratumoral regulatory T cells., PMID:36370665
Basigin is necessary for normal decidualization of human uterine stromal cells., PMID:36303457
The disulfide catalyst QSOX1 maintains the colon mucosal barrier by regulating Golgi glycosyltransferases., PMID:36245281
Disulfide bond formation and redox regulation in the Golgi apparatus., PMID:36214053
Comprehensive analysis of endoplasmic reticulum-related and secretome gene expression profiles in the progression of non-alcoholic fatty liver disease., PMID:36034446
FN1 encoding fibronectin as a pivotal signaling gene for therapeutic intervention against pancreatic cancer., PMID:35982245
Transcriptome-Wide Mapping of Small-Molecule RNA-Binding Sites in Cells Informs an Isoform-Specific Degrader of QSOX1 mRNA., PMID:35737519
Protein Network Analysis of Whole Exome Sequencing of Severe Preeclampsia., PMID:35719905
Polarized epithelium-sperm co-culture system reveals stimulatory factors for the secretion of mouse epididymal quiescin sulfhydryl oxidase 1., PMID:35228412
iTRAQ-based proteomics of testicular interstitial fluid during aging in mice., PMID:34482126
Identification of hub genes in thyroid carcinoma to predict prognosis by integrated bioinformatics analysis., PMID:34167437
Systems genetics in diversity outbred mice inform BMD GWAS and identify determinants of bone strength., PMID:34099702
Conformational switches and redox properties of the colon cancer-associated human lectin ZG16., PMID:34077620
Multiomics Analysis of Transcriptome, Epigenome, and Genome Uncovers Putative Mechanisms for Dilated Cardiomyopathy., PMID:33860048
Proteomic Analyses of Fibroblast- and Serum-Derived Exosomes Identify QSOX1 as a Marker for Non-invasive Detection of Colorectal Cancer., PMID:33802764
Quiescin sulfhydryl oxidase 1 promotes sorafenib-induced ferroptosis in hepatocellular carcinoma by driving EGFR endosomal trafficking and inhibiting NRF2 activation., PMID:33770521
Identification of Key Genes Associated with Changes in the Host Response to Severe Burn Shock: A Bioinformatics Analysis with Data from the Gene Expression Omnibus (GEO) Database., PMID:33293847
Capillary electrophoresis electrospray ionization-mass spectrometry for peptidomics-based processing site determination., PMID:33008600
QSOX1 promotes mitochondrial apoptosis of hepatocellular carcinoma cells during anchorage-independent growth by inhibiting lipid synthesis., PMID:32863002
Quiescin Sulfhydryl Oxidase 1 Regulates the Proliferation, Migration and Invasion of Human Glioblastoma Cells via PI3K/Akt Pathway., PMID:32606784
Putative Biomarkers for Malignant Pleural Mesothelioma Suggested by Proteomic Analysis of Cell Secretome., PMID:32345664
Obesity-associated methylation in breast tumors: a possible link to disparate outcomes?, PMID:32236829
Peri/Epicellular Thiol Oxidoreductases as Mediators of Extracellular Redox Signaling., PMID:31910038
Quiescin/sulfhydryl oxidase 1b (QSOX1b) induces migration and proliferation of vascular smooth muscle cells by distinct redox pathways., PMID:31812669
Peripheral Blood RNA Levels of QSOX1 and PLBD1 Are New Independent Predictors of Left Ventricular Dysfunction After Acute Myocardial Infarction., PMID:31756302
Molecular Inhibitor of QSOX1 Suppresses Tumor Growth In Vivo., PMID:31575656
Optimizing antibody affinity and stability by the automated design of the variable light-heavy chain interfaces., PMID:31442220
A conserved major facilitator superfamily member orchestrates a subset of O-glycosylation to aid macrophage tissue invasion., PMID:30910009
cis-Proline mutants of quiescin sulfhydryl oxidase 1 with altered redox properties undermine extracellular matrix integrity and cell adhesion in fibroblast cultures., PMID:30367560
For research use only. Not for human or drug use.
