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Research Grade Tavolimab (DHE43203)

Host species:Humanized
Isotype:IgG1-kappa
Applications:Research Grade Biosimilar
Expression system:Mammalian Cells
Overview

Catalog No.

DHE43203

Expression system

Mammalian Cells

Species reactivity

Human

Host species

Humanized

Isotype

IgG1-kappa

Clonality

Monoclonal

Target

ACT35 antigen, TXGP1L, TAX transcriptionally-activated glycoprotein 1 receptor, Tumor necrosis factor receptor superfamily member 4, TNFRSF4, OX40L receptor, CD134

Concentration

0.98 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P43489

Applications

Research Grade Biosimilar

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Alternative Names

Tavolixizumab, MEDI0562, CAS: 1635395-25-3

Clone ID

Tavolimab

Data Image
  • SDS-PAGE
    SDS PAGE for Tavolimab
  • Bioactivity
    Detects CD134/TNFRSF4/OX40 in indirect ELISAs.
References

COVID-19 and rheumatic autoimmune systemic diseases: report of a large Italian patients series, PMID: 32852623

A randomized controlled trial of rituximab for the treatment of severe cryoglobulinemic vasculitis, PMID: 22147661

Hypersensitivity reactions during treatment with biological agents, PMID: 26751942

Salivary Gland Pathology in IgG4-Related Disease: A Comprehensive Review, PMID: 29805984

Rituximab as a novel treatment for heart failure: evidence from a case series, PMID: 31911994

A bargaining experiment on heterogeneity and side deals in climate negotiations, PMID: 32055080

Mixed cryoglobulinemia and mortality: a review of the literature, PMID: 19026151

Skull-Base Inflammatory Pseudotumor Involving the Trigeminal and Facial Nerves: A Singular Presentation of a Rare Disease, PMID: 32133412

Preliminary classification criteria for the cryoglobulinaemic vasculitis, PMID: 21571735

How HCV has changed the approach to mixed cryoglobulinemia, PMID: 19646357

Cancer-associated myositis: a 35-year retrospective study of a monocentric cohort, PMID: 24322453

Epidemiology of systemic sclerosis: a multi-database population-based study in Tuscany (Italy), PMID: 33596949

A clinical prediction rule for lymphoma development in primary Sjögren's syndrome, PMID: 22337248

18-FDG PET for large vessel vasculitis diagnosis and follow-up, PMID: 33337989

The use of rituximab in idiopathic inflammatory myopathies: description of a monocentric cohort and review of the literature, PMID: 29976041

Treatment strategy introducing immunosuppressive drugs with glucocorticoids ab initio or very early in giant cell arteritis: A multicenter retrospective controlled study, PMID: 33305250

Clinically amyopathic dermatomyositis: analysis of a monocentric cohort, PMID: 24872214

COVID-19 in Italian patients with rheumatic autoimmune systemic diseases, PMID: 33055077

Anakinra in COVID-19 therapy: what have we learned from adult-onset Still's disease?, PMID: 32456767

FPLC and Ro/SS-A purification, PMID: 1570500

Mutations in MFSD8/CLN7 are a frequent cause of variant-late infantile neuronal ceroid lipofuscinosis, PMID: 19177532

A case of intravascular large B cell lymphoma with brain involvement mimicking Progressive Multifocal Leukoencephalopathy, PMID: 34425062

Selexipag may be effective in inducing digital ulcers healing in patients with systemic sclerosis, PMID: 32452347

Treatment with rituximab in patients with mixed cryoglobulinemia syndrome: results of multicenter cohort study and review of the literature, PMID: 21821153

Safety and effectiveness of biosimilar of Rituximab CT-P10 in the treatment of cryoglobulinemic vasculitis: the MARBLe study (Mixed cryoglobulinemiA Rituximab BiosimiLar), PMID: 32524338

[Primary Sjogren's syndrome: clinical and serological feature of a single centre], PMID: 16380752

Validation of the classification criteria for cryoglobulinaemic vasculitis, PMID: 24994905

Alteration of microcirculation is a hallmark of very early systemic sclerosis patients: a laser speckle contrast analysis, PMID: 23073231

Sjögren's Syndrome Disease Damage Index and disease activity index: scoring systems for the assessment of disease damage and disease activity in Sjögren's syndrome, derived from an analysis of a cohort of Italian patients, PMID: 17599741

Cyclophosphamide and methotrexate in Susac's Syndrome: a successful sequential therapy in a case with involvement of the cerebellum, PMID: 24794491

Renal Involvement in IgG4-Related Disease: From Sunlight to Twilight, PMID: 33869249

Undifferentiated connective tissue disease: analysis of 83 patients with a minimum followup of 5 years, PMID: 12415590

Pregnancy outcome in patients with undifferentiated connective tissue disease: a preliminary study on 25 pregnancies, PMID: 12090565

Inequality, communication, and the avoidance of disastrous climate change in a public goods game, PMID: 21730154

Resilience in the global food system, PMID: 32818038

Hyperviscosity syndrome in cryoglobulinemia: clinical aspects and therapeutic considerations, PMID: 14631547

Retreatment regimen of rituximab monotherapy given at the relapse of severe HCV-related cryoglobulinemic vasculitis: Long-term follow up data of a randomized controlled multicentre study, PMID: 26255249

A simple method for the biochemical purification of Ro/SS-A antigen, PMID: 2760465

Thigh magnetic resonance imaging for the evaluation of disease activity in patients with idiopathic inflammatory myopathies followed in a single center, PMID: 27279002

Recommendations for the management of mixed cryoglobulinemia syndrome in hepatitis C virus-infected patients, PMID: 21303705

Mediators of angiogenesis and fibrosis in IgG4-related disease, PMID: 29243036

Overlap of ACA-positive systemic sclerosis and Sjögren's syndrome: a distinct clinical entity with mild organ involvement but at high risk of lymphoma, PMID: 23343785

Bosentan and sildenafil: successful treatment in a sclerodermic patient with refractory ulcers, PMID: 23877412

Severe thrombocytopenic purpura after meningococcal C vaccination in a woman affected by systemic lupus erythematosus, PMID: 27748652

Churg-Strauss syndrome: clinical and serological features of 19 patients from a single Italian centre, PMID: 12422002

Primary Sjogren's syndrome as a multi-organ disease: impact of the serological profile on the clinical presentation of the disease in a large cohort of Italian patients, PMID: 24369420

IL-1 family cytokines and receptors in IgG4-related disease, PMID: 28823915

Evaluation of S-adenosylmethionine in primary fibromyalgia. A double-blind crossover study, PMID: 3318438

Lung involvement in Sjögren's syndrome: a comparison between patients with primary and with secondary syndrome, PMID: 4026406

Inferior rectus myositis: a rare cause of painful ophthalmoplegia and a therapeutic challenge, PMID: 22752122

Datasheet

Document Download

Research Grade Tavolimab.pdf

 

$ 328
Product specifications
100 μg 328 1 mg 1314

Contact Information

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Research Grade Tavolimab [DHE43203]
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