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Anti-ACE2 Polyclonal Antibody

Catalog #:   PHJ51601 Specific References (50) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: ELISA, IHC, WB
Accession: Q9BYF1
Overview

Catalog No.

PHJ51601

Species reactivity

Human, Mouse, Rat

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human ACE2 (Leu391-Ser740).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

Angiotensin-converting enzyme homolog,ACE2,ACEH,Metalloprotease MPROT15,Angiotensin-converting enzyme-related carboxypeptidase,Angiotensin-converting enzyme 2,ACE-related carboxypeptidase

Purification

Purified by antigen affinity column.

Accession

Q9BYF1

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Data Image
  • WESTERN BLOT
    Recombinant Protein lysates were subjected to SDS PAGE followed by western blot with ACE2 antibody (PHJ51601) at 1 μg/ml.

    Lane 1: Recombinant protein

    Second Ab: Goat Anti-Rabbit IgG H&L Polyclonal antibody, HRP (PTB96431) at 0.1 μg/mL.

    Predict MW: 43 kDa
    Observed MW: 43 kDa
References

Potential blocker of SARS-CoV entry and a narrow functionality of its spike protein motifs on Qubevirus platform., PMID:40516871

Humoral and cellular immune responses in people living with HIV following successive COVID-19 vaccine booster doses., PMID:40513829

Comprehensive analysis of SARS-CoV-2 Spike evolution: epitope classification and immune escape prediction., PMID:40510757

Development and Validation of Novel Cell-free Direct Neutralization Assay for SARS-CoV-2., PMID:40499786

Predicting high-fitness viral protein variants with Bayesian active learning and biophysics., PMID:40489612

Deletion of the Envelope gene attenuates SARS-CoV-2 infection by altered Spike localization and increased cell-to-cell transmission., PMID:40475451

Differential patterns of cross-protection against antigenically distinct variants in small animal models of SARS-CoV-2 infection., PMID:40467943

Unveiling the structural spectrum of SARS-CoV-2 fusion by in situ cryo-ET., PMID:40461447

Multiplex ACE2-RBD binding inhibition assay: An integrated tool for assessing neutralizing antibodies to SARS-CoV-2 variants and protection against breakthrough infections., PMID:40447072

ACE2, a therapeutic target of COVID-19, needs to be treated with caution., PMID:40439840

Antibody Response Against SARS-CoV-2 Spike Protein in People with HIV After COVID-19 Vaccination., PMID:40432092

Dynamic Interaction Between SARS-CoV-2 and Influenza A Virus Infection in Human Respiratory Tissues and Cells., PMID:40431161

Immune evasion, infectivity, and membrane fusion of the SARS-CoV-2 JN.1 variant., PMID:40413500

Use of a Multiplex Immunoassay Platform to Investigate Multifaceted Antibody Responses in SARS-CoV-2 Vaccinees with and Without Prior Infection., PMID:40406038

Nanoparticle-supported, rapid, digital quantification of neutralizing antibodies against SARS-CoV-2 variants., PMID:40383030

Biophysics of SARS-CoV-2 spike protein's receptor-binding domain interaction with ACE2 and neutralizing antibodies: from computation to functional insights., PMID:40376405

Exploring Diverse Binding Mechanisms of Broadly Neutralizing Antibodies S309, S304, CYFN-1006 and VIR-7229 Targeting SARS-CoV-2 Spike Omicron Variants: Integrative Computational Modeling Reveals Balance of Evolutionary and Dynamic Adaptability in Shaping Molecular Determinants of Immune Escape., PMID:40376091

Autoencoder techniques for survival analysis on renal cell carcinoma., PMID:40373089

The underlying mechanism behind the different outcomes of COVID-19 in children and adults., PMID:40370452

Infectious potential and circulation of SARS-CoV-2 in wild rats., PMID:40354427

Rapid response to fast viral evolution using AlphaFold 3-assisted topological deep learning., PMID:40352163

Advances in COVID-19 Therapeutics: Exploring the role of lectins and protease inhibitors., PMID:40349995

Computationally designed proteins mimic antibody immune evasion in viral evolution., PMID:40345199

Case Report: Co-occurrence of tubulitis and SARS-CoV-2 specific T-cells in a kidney transplant recipient., PMID:40343198

Engineered bacteria as an orally administered anti-viral treatment and immunization system., PMID:40340796

Computational Design and Evaluation of Peptides to Target SARS-CoV-2 Spike-ACE2 Interaction., PMID:40333723

Entry Efficiency, Protease Dependence, and Antibody-Mediated Neutralization of SARS-CoV-2 Sublineages KP.3.1.1 and XEC., PMID:40333265

Serum angiotensin type-1 receptor autoantibodies and neurofilament light chain as markers of neuroaxonal damage in post-COVID patients., PMID:40330487

Cryo-EM reveals conformational variability in the SARS-CoV-2 spike protein RBD induced by two broadly neutralizing monoclonal antibodies., PMID:40330036

Temporal correlations between RBD-ACE2 blocking and binding antibodies to SARS-CoV-2 variants in CoronaVac-vaccinated individuals and their persistence in COVID-19 patients., PMID:40328892

Identification of a nanobody able to catalyze the destruction of the spike-trimer of SARS-CoV-2., PMID:40317451

Comparison of the ACE2 receptor and monoclonal antibodies immobilisation strategies for the sensitive detection of SARS-CoV-2 variants of concern., PMID:40316389

Structural insights into the receptor-binding domain of bat coronavirus ZXC21., PMID:40306273

Reduced cross-protective potential of Omicron compared to ancestral SARS-CoV-2 spike vaccines against potentially zoonotic coronaviruses., PMID:40295830

Lower Expression of SARS-CoV-2 Host Cell Entry Genes in the Intestinal Mucosa of IBD Patients With Quiescent or Mildly Active Disease., PMID:40279370

Aerosol Delivery of Hesperetin-Loaded Nanoparticles and Immunotherapy Increases Survival in a Murine Lung Cancer Model., PMID:40278452

Engineered ACE2 decoy in dry powder form for inhalation: A novel therapy for SARS-CoV-2 variants., PMID:40276779

Sequential SARS-CoV-2 mRNA Vaccination Induces Anti-Idiotype (Anti-ACE2) Antibodies in K18 Human ACE2 Transgenic Mice., PMID:40266063

Recombinant receptor-binding motif of spike COVID-19 vaccine candidate induces SARS-CoV-2 neutralizing antibody response., PMID:40256231

Heparan sulfate proteoglycans remodel SARS-CoV-2 spike conformation to allow integrin interaction and infection of endothelial cells., PMID:40248367

Viral escape-inspired framework for structure-guided dual bait protein biosensor design., PMID:40233103

Integrated renin angiotensin system dysregulation and immune profiles predict COVID-19 disease severity in a South African cohort., PMID:40229302

Anti-S2 antibodies responsible for the SARS-CoV-2 infection-induced serological cross-reactivity against MERS-CoV and MERS-related coronaviruses., PMID:40226608

Structural basis and mode of action for two broadly neutralizing nanobodies targeting the highly conserved spike stem-helix of sarbecoviruses including SARS-CoV-2 and its variants., PMID:40215243

Antibody evasiveness of SARS-CoV-2 subvariants KP.3.1.1 and XEC., PMID:40202847

Capture of fusion-intermediate conformations of SARS-CoV-2 spike requires receptor binding and cleavage at either the S1/S2 or S2' site., PMID:40198676

Strain- and vaccine-specific effects of serum antibodies in the protection of intestinal SARS-CoV-2 infection., PMID:40196264

COVID-19 and Its Effects on the Hepatobiliary System: A Literature Review., PMID:40190856

A global collaboration for systematic analysis of broad-ranging antibodies against the SARS-CoV-2 spike protein., PMID:40184253

Rice-derived SARS-CoV-2 glycoprotein S1 subunit vaccine elicits humoral and cellular immune responses., PMID:40183251

Datasheet
$ 170
Product specifications
50 μg 170 100 μg 280

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For research use only. Not for human or drug use.

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Anti-ACE2 Polyclonal Antibody [PHJ51601]
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