Catalog No.
YHN54201
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ala745-Val1087
Predicted molecular weight
40.84 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9Y6K5
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
2-5A synthase 3, p100 OAS, p100OAS, (2-5')oligo(A) synthase 3, 2'-5'-oligoadenylate synthase 3, OAS3
IRF2-driven upregulation of OAS3 promotes AML cell proliferation by modulating the JAK-STAT signaling pathway., PMID:40414009
Identification of novel autoantibodies in Sjögren's disease., PMID:39963128
Casein Glycomacropeptide Regulates Gene Expression in Intestinal Epithelial Cells: Effect of Simulated Gastrointestinal Digestion and Peptide Microencapsulation., PMID:39921639
BRN3A, a transcription factor, regulates the expression of genes involved in biological processes shaping the HPV induced cervical cancer., PMID:39873931
Heterogeneity of OAS family expression in tuberculosis and the impact of different sample selection: a comprehensive analysis., PMID:39864306
Investigating the clinical significance of OAS family genes in breast cancer: an in vitro and in silico study., PMID:39633486
OAS3 Deubiquitination Due to E3 Ligase TRIM21 Downregulation Promotes Epithelial Cell Apoptosis and Drives Sepsis-induced Acute Lung Injury., PMID:39494334
Causal effect of psoriasis on aortic valve stenosis: a two-sample Mendelian randomization study., PMID:39483265
A CRISPR-Cas9 knockout screening identifies IRF2 as a key driver of OAS3/RNase L-mediated RNA decay during viral infection., PMID:39475651
Analysis of Key Genes Related to Systemic Lupus Erythematosus and COVID-19., PMID:39129283
LncRNA XIST/miR-381-3P/STAT1 axis as a potential biomarker for lupus nephritis., PMID:39126180
The nuclear matrix protein HNRNPU restricts hepatitis B virus transcription by promoting OAS3-based activation of host innate immunity., PMID:39011773
A comparative analysis of RNA-Seq and NanoString technologies in deciphering viral infection response in upper airway lung organoids., PMID:38957806
Profiling of Early Immune Responses to Vaccination Using THP-1-Derived Dendritic Cells., PMID:38791547
Condensation of RNase L promotes its rapid activation in response to viral infection in mammalian cells., PMID:38771918
TYK2, IFITM3, IFNAR2 and OAS3 single-nucleotide polymorphisms among severe COVID-19 ICU patients in Morocco., PMID:38760017
Distinct domain organization and diversity of 2'-5'-oligoadenylate synthetases., PMID:38603810
[Investigation of the immune profile of multiple myeloma patients achieving long-term survival after autologous stem cell transplantation]., PMID:38561281
Age-related transcript changes in type I interferon signaling in children and adolescents with long COVID., PMID:38522030
Label-free quantitative proteomics reveals the mechanisms of Aurora kinase B in renal cell carcinoma., PMID:38516642
Identification of EPSTI1 as a new potential biomarker for SLE based on GEO database., PMID:38507132
Screening of Genes Associated with Immune Infiltration of Discoid Lupus Erythematosus Based on Weighted Gene Co-expression Network Analysis., PMID:38451400
Redox regulation of m6A methyltransferase METTL3 in β-cells controls the innate immune response in type 1 diabetes., PMID:38409327
Biological analysis of the potential pathogenic mechanisms of Infectious COVID-19 and Guillain-Barré syndrome., PMID:38115996
Inborn errors of type I interferon immunity in patients with symptomatic acute hepatitis E., PMID:38079352
Identifying the Interaction Between Tuberculosis and SARS-CoV-2 Infections via Bioinformatics Analysis and Machine Learning., PMID:37991568
The Relationship between COVID-19 Severity in Children and Immunoregulatory Gene Polymorphism., PMID:37896870
The Transcriptome Landscape of the In Vitro Human Airway Epithelium Response to SARS-CoV-2., PMID:37569398
Bioinformatics and systems biology analysis revealed PMID26394986-Compound-10 as potential repurposable drug against covid-19., PMID:37534820
Host Factor Nucleophosmin 1 (NPM1/B23) Exerts Antiviral Effects against Chikungunya Virus by Its Interaction with Viral Nonstructural Protein 3., PMID:37409962
Characterization of virus-mediated autoimmunity and the consequences for pathological process in patients with systemic lupus erythematosus., PMID:37369873
Occludin Regulates HIV-1 Infection by Modulation of the Interferon Stimulated OAS Gene Family., PMID:37209263
Identification of key biomarkers associated with immune cells infiltration for myocardial injury in dermatomyositis by integrated bioinformatics analysis., PMID:37118825
2-5A-Mediated decay (2-5AMD): from antiviral defense to control of host RNA., PMID:36939319
SARS-CoV-2 infection in children: A 24 months experience with focus on risk factors in a pediatric tertiary care hospital in Milan, Italy., PMID:36873632
The HIV Restriction Factor Profile in the Brain Is Associated with the Clinical Status and Viral Quantities., PMID:36851531
Redox Regulation of m 6 A Methyltransferase METTL3 in Human β-cells Controls the Innate Immune Response in Type 1 Diabetes., PMID:36824909
Rhinovirus C causes heterogeneous infection and gene expression in airway epithelial cell subsets., PMID:36796588
An integrated strategy to identify COVID-19 causal genes and characteristics represented by LRRC37A2., PMID:36794676
Occludin regulates HIV-1 infection by modulation of the interferon stimulated OAS gene family., PMID:36778388
Development of immortalized feline respiratory epithelial cells in an air-liquid-interface culture system for feline herpesvirus-1 study., PMID:36738933
Neuro-immune deconvolution analysis of OAS3 as a transcriptomic central node in HIV-associated neurocognitive disorders., PMID:36706688
Orientia tsutsugamushi Infection Stimulates Syk-Dependent Responses and Innate Cytosolic Defenses in Macrophages., PMID:36678402
Integrative Multiomics and Regulatory Network Analyses Uncovers the Role of OAS3, TRAFD1, miR-222-3p, and miR-125b-5p in Hepatitis E Virus Infection., PMID:36672782
Mucosal Gene Expression in Response to SARS-CoV-2 Is Associated with Viral Load., PMID:36656015
IFI44L as a novel epigenetic silencing tumor suppressor promotes apoptosis through JAK/STAT1 pathway during lung carcinogenesis., PMID:36584854
Combined proteomics and single cell RNA-sequencing analysis to identify biomarkers of disease diagnosis and disease exacerbation for systemic lupus erythematosus., PMID:36524113
Identification of immune-related biomarkers and construction of regulatory network in patients with atherosclerosis., PMID:36437453
Establishment and analysis of a disease risk prediction model for the systemic lupus erythematosus with random forest., PMID:36405750
Identification of novel interferon responsive protein partners of human leukocyte antigen A (HLA-A) using cross-linking mass spectrometry (CLMS) approach., PMID:36371414
For research use only. Not for human or drug use.
