Catalog No.
YHB55002
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Leu117
Predicted molecular weight
16.97 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O95166
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
MM46, GABA(A) receptor-associated protein, GABARAP, Gamma-aminobutyric acid receptor-associated protein, FLC3B
Exploring human plasma proteomic variations in mucolipidosis type IV., PMID:40486934
Elimination of intra-hepatocytic malaria parasites is driven by non-canonical autophagy but not nitric oxide production., PMID:40463965
γ-Aminobutyric acid modulates terpene biosynthesis through the ATG8a-mediated pathway., PMID:40424537
Exploring Dapagliflozin's Influence on Autophagic Flux in Mania-like Behaviour: Insights from the LKB1/AMPK/LC3 Pathway in a Mouse Model., PMID:40402300
Positional specialization of LIR motifs in RavZ and the autophagy-related protein ATG4B., PMID:40395991
ATG5 is dispensable for ATG8ylation of cellular proteins., PMID:40395522
Highlighting the hidden: monitoring the avidity-driven association of a fluorescent GABARAP tandem with microtubules in living cells., PMID:40395516
Biochemical investigation of LC3/GABARAP-ligand interaction as an important quality measure for LC3/GABARAP-targeting small molecules: addendum to the guidelines (4th edition)., PMID:40344429
Reticulon-dependent ER-phagy mediates adaptation to heat stress in C. elegans., PMID:40328253
AlphaFold2 SLiM screen for LC3-LIR interactions in autophagy., PMID:40320752
Isoleucine Side Chains as Reporters of Conformational Freedom in Protein Folding Studied by DNP-Enhanced NMR., PMID:40285725
Molecular and functional identification of a LC3C homolog in large yellow croaker (Larimichthys crocea)., PMID:40228590
TFEB and TFE3 regulate STING1-dependent immune responses by controlling type I interferon signaling., PMID:40195022
TGFB signaling induces mitophagy via PLSCR3-mediated cardiolipin externalization in conjunction with a BNIP3L/NIX-, BNIP3-, and FUNDC1-dependent mechanism., PMID:40119553
Oncogenic RAS induces a distinctive form of non-canonical autophagy mediated by the P38-ULK1-PI4KB axis., PMID:40055523
LRRK2, lysosome damage, and Parkinson's disease., PMID:39983584
STING-induced noncanonical autophagy regulates endolysosomal homeostasis., PMID:39982740
Exploring Arylidene-Indolinone Ligands of Autophagy Proteins LC3B and GABARAP., PMID:39967642
Development of selective deconjugases for membrane-anchored LC3A/B in post-mitotic neurons., PMID:39940005
Mechanisms and roles of membrane-anchored ATG8s., PMID:39936034
Inhibition of GABARAP or GABARAPL1 prevents aminoglycoside- induced hearing loss., PMID:39928869
Saikosaponin D exacerbates acetaminophen-induced liver injury by sabotaging GABARAP-SNARE complex assembly in protective autophagy., PMID:39874796
Induction of lysosome biogenesis is a novel function of the CGAS-STING1 pathway., PMID:39835593
N-acetyltransferase 10 impedes EZH2/H3K27me3/GABARAP axis mediated autophagy and facilitates lung cancer tumorigenesis through enhancing SGK2 mRNA acetylation., PMID:39814292
A STING-CASM-GABARAP pathway activates LRRK2 at lysosomes., PMID:39812709
Structure of the human autophagy factor EPG5 and the molecular basis of its conserved mode of interaction with Atg8-family proteins., PMID:39809444
Mechanical compressive forces increase PI3K output signaling in breast and pancreatic cancer cells., PMID:39746759
NS1 binding protein regulates stress granule dynamics and clearance by inhibiting p62 ubiquitination., PMID:39738171
Blocking autophagosome closure manifests the roles of mammalian Atg8-family proteins in phagophore formation and expansion during nutrient starvation., PMID:39694607
The cGAS-STING pathway activates transcription factor TFEB to stimulate lysosome biogenesis and pathogen clearance., PMID:39689715
Endogenous interactomes of MFN1 and MFN2 provide novel insights into interorganelle communication and autophagy., PMID:39675054
Non-lytic spread of poliovirus requires the nonstructural protein 3CD., PMID:39665531
Accurate de novo design of high-affinity protein binding macrocycles using deep learning., PMID:39605685
Critical assessment of LC3/GABARAP ligands used for degrader development and ligandability of LC3/GABARAP binding pockets., PMID:39587067
Plasmodium berghei liver stage parasites exploit host GABARAP proteins for TFEB activation., PMID:39572689
Exploring Arylidene-Indolinone Ligands of Autophagy Proteins LC3B and GABARAP., PMID:39554136
Recruitment of autophagy initiator TAX1BP1 advances aggrephagy from cargo collection to sequestration., PMID:39448883
Multiplex genomic tagging of mammalian ATG8s to study autophagy., PMID:39433127
A TBK1-independent primordial function of STING in lysosomal biogenesis., PMID:39423796
SIGMAR1/Sigma-1 receptor: a key regulator in stabilizing and translating LC3B mRNA for autophagosome formation., PMID:39369298
Identification of the GABARAP binding determinant in PI4K2A., PMID:39344512
GABA(A) Receptor Activation Drives GABARAP-Nix Mediated Autophagy to Radiation-Sensitize Primary and Brain-Metastatic Lung Adenocarcinoma Tumors., PMID:39335139
ER-phagy restrains inflammatory responses through its receptor UBAC2., PMID:39284914
Cytosolic FKBPL and ER-resident CKAP4 co-regulates ER-phagy and protein secretion., PMID:39251576
Structural Analyses of a GABARAP~ATG3 Conjugate Uncover a Novel Non-covalent Ubl-E2 Backside Interaction., PMID:39185234
Artificial targeting of autophagy components to mitochondria reveals both conventional and unconventional mitophagy pathways., PMID:39177530
GABARAP interacts with EGFR - supporting the unique role of this hAtg8 protein during receptor trafficking., PMID:39160442
WIPI2b recruitment to phagophores and ATG16L1 binding are regulated by ULK1 phosphorylation., PMID:39152217
Thermodynamic Characterization of LC3/GABARAP:Ligand Interactions by Isothermal Titration Calorimetry., PMID:39115670
High-Throughput Screening for LC3/GABARAP Binders Utilizing the Fluorescence Polarization Assay., PMID:39115669
For research use only. Not for human or drug use.
