Catalog No.
YHA35302
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Val63-Leu108
Predicted molecular weight
33.46 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O14944
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
EREG, Proepiregulin, EPR
Succinylation-related molecular activities in cancer: metabolic adaptations, immune landscape, and prognostic significance in colorectal cancer., PMID:40463370
Changes in Gene Transcription in Cumulus Cells from Women of Advanced Maternal Age under the Influence of Extracellular Vesicles from Follicular Fluid of Young Donors., PMID:40448879
Spontaneous brain activity in patients with type 2 diabetes: linking serum neuroproteins to cognitive ability., PMID:40426217
Embryo-derived human chorionic gonadotropin promotes human decidualization through activating epithelial prostaglandin F2α secretion., PMID:40398806
EGFR-mediated local invasiveness and response to Cetuximab in head and neck cancer., PMID:40121428
Manganese-induced Precocious Puberty Alters Mammary Epithelial Cell Proliferation in Female Rats., PMID:40105700
Coordinated differentiation of human intestinal organoids with functional enteric neurons and vasculature., PMID:40043706
The X-Linked Tumor Suppressor TSPX Regulates Genes Involved in the EGFR Signaling Pathway and Cell Viability to Suppress Lung Adenocarcinoma., PMID:39858622
Hyodeoxycholic acid inhibits colorectal cancer proliferation through the FXR/EREG/EGFR axis., PMID:39834394
Identification of possible drug treatment targets and related immune cell infiltration properties in acute myeloid leukemia utilizing robust rank aggregation algorithm., PMID:39813619
Neo-adjuvant FOLFOX with and without panitumumab for patients with KRAS-wt locally advanced colon cancer: results following an extended biomarker panel on the FOxTROT trial embedded phase II population., PMID:39805350
Polysaccharides of Atractylodes Macrocephala Koidz Alleviate LPS-Induced Bursa of Fabricius Injury in Goslings by Inhibiting EREG Expression., PMID:39795027
Effect of human chorionic gonadotropin on oocyte maturation and developmental competence in buffalo., PMID:39787661
Non-Genotoxic and Environmentally Relevant Lower Molecular Weight Polycyclic Aromatic Hydrocarbons Significantly Increase Tumorigenicity of Benzo[a]pyrene in a Lung Two-Stage Mouse Model., PMID:39771097
dEREGulated pathways: unraveling the role of epiregulin in skin, kidney, and lung fibrosis., PMID:39750963
BRAF-activated ARSI suppressed EREG-mediated ferroptosis to promote BRAFV600E (mutant) papillary thyroid carcinoma progression and sorafenib resistance., PMID:39744439
Antibody-Drug Conjugates Targeting the EGFR Ligand Epiregulin Elicit Robust Antitumor Activity in Colorectal Cancer., PMID:39693606
Identification and validation of apoptosis-related genes in acute myocardial infarction based on integrated bioinformatics methods., PMID:39650552
Low-affinity ligands of the epidermal growth factor receptor are long-range signal transmitters in collective cell migration of epithelial cells., PMID:39546398
Ubiquitin-related gene markers predict immunotherapy response and prognosis in patients with epithelial ovarian carcinoma., PMID:39448713
Lumican/Lumikine Promotes Healing of Corneal Epithelium Debridement by Upregulation of EGFR Ligand Expression via Noncanonical Smad-Independent TGFβ/TBRs Signaling., PMID:39404363
Low-affinity ligands of the epidermal growth factor receptor are long-range signal transmitters during collective cell migration of epithelial cells., PMID:39399773
Inhibition of EREG/ErbB/ERK by Astragaloside IV reversed taxol-resistance of non-small cell lung cancer through attenuation of stemness via TGFβ and Hedgehog signal pathway., PMID:39373858
Embryo-Derived Cathepsin B Promotes Implantation and Decidualization by Activating Pyroptosis., PMID:39316370
Involvement of HDAC2-mediated kcnq2/kcnq3 genes transcription repression activated by EREG/EGFR-ERK-Runx1 signaling in bone cancer pain., PMID:39192337
Annotation and automated segmentation of single-molecule localisation microscopy data., PMID:39092628
EREG silencing inhibits tumorigenesis via inactivating ERK/p38 MAPK pathway in pancreatic ductal adenocarcinoma., PMID:38972433
Stabilization of EREG via STT3B-mediated N-glycosylation is critical for PDL1 upregulation and immune evasion in head and neck squamous cell carcinoma., PMID:38945975
The growth factors amphiregulin and epiregulin are novel stimulators of feline ovarian granulosa cell functions., PMID:38828525
A bioinformatics approach to systematically analyze the molecular patterns of monkeypox virus-host cell interactions., PMID:38737277
EGF-like growth factors upregulate pentraxin 3 expression in human granulosa-lutein cells., PMID:38720330
Role of Epiregulin on Lipopolysaccharide-Induced Hepatocarcinogenesis as a Mediator via EGFR Signaling in the Cancer Microenvironment., PMID:38673992
Integration analysis of single-cell transcriptome reveals specific monocyte subsets associated with melanoma brain and leptomeningeal metastasis., PMID:38616506
The growth factor EPIREGULIN promotes basal progenitor cell proliferation in the developing neocortex., PMID:38514807
Collagen I-induced VCAN/ERK signaling and PARP1/ZEB1-mediated metastasis facilitate OSBPL2 defect to promote colorectal cancer progression., PMID:38267463
IGF2BP2 promotes cell invasion and epithelial-mesenchymal transition through Src-mediated upregulation of EREG in oral cancer., PMID:38250159
Exploring biomarkers in trigeminal neuralgia patients operated with microvascular decompression: A comparison with multiple sclerosis patients and non-neurological controls., PMID:38158702
Ferroptosis-related genes prognostic signature for pancreatic cancer and immune infiltration: potential biomarkers for predicting overall survival., PMID:38007403
Prognostic and predictive biomarkers for anti-EGFR monoclonal antibody therapy in RAS wild-type metastatic colorectal cancer: a systematic review and meta-analysis., PMID:37974093
Inhibition of transforming growth factor-β signals suppresses tumor formation by regulation of tumor microenvironment networks., PMID:37972575
A novel selective ERK1/2 inhibitor, Laxiflorin B, targets EGFR mutation subtypes in non-small-cell lung cancer., PMID:37816856
[Risk modeling based on HER-2 related genes for bladder cancer survival prognosis assessment]., PMID:37807731
Tumor-associated monocytes promote mesenchymal transformation through EGFR signaling in glioma., PMID:37652019
Towards Multiomics-Based Dissection of Anti-EGFR Sensitivity in Colorectal Cancer., PMID:37594733
SOCS1 as a Biomarker Candidate for HPV Infection and Prognosis of Head and Neck Squamous Cell Carcinomas., PMID:37504269
Prolyl 4-hydroxylase subunit beta (P4HB) could serve as a prognostic and radiosensitivity biomarker for prostate cancer patients., PMID:37480146
Associations between AI-Assisted Tumor Amphiregulin and Epiregulin IHC and Outcomes from Anti-EGFR Therapy in the Routine Management of Metastatic Colorectal Cancer., PMID:37363997
ELF3 suppresses gallbladder cancer development through downregulation of the EREG/EGFR/mTOR complex 1 signalling pathway., PMID:37345534
MicroRNA-1179 targets Epiregulin (EREG) regulates the proliferation and metastasis of human multiple myeloma cells., PMID:37329522
For research use only. Not for human or drug use.
