Catalog No.
YVV40401
Expression system
E. coli
Species
Epstein-Barr virus (strain B95-8) (HHV-4) (Human herpesvirus 4)
Protein length
Leu175-Phe245
Predicted molecular weight
36.56 kDa
Nature
Recombinant
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P03206
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Lytic switch protein BZLF1, EB1, Protein Z, Trans-activator protein BZLF1, Zta, bZIP transcription factor ZEBRA, BZLF1
Note
For research use only.
The danger molecule HMGB1 cooperates with the NLRP3 inflammasome to sustain expression of the EBV lytic switch protein in Burkitt lymphoma cells., PMID:34922257
Molecular Basis of Epstein-Barr Virus Latency Establishment and Lytic Reactivation., PMID:34960613
Epstein-Barr virus infection patterns in nodular lymphocyte-predominant Hodgkin lymphoma., PMID:35322462
Reduced IRF4 expression promotes lytic phenotype in Type 2 EBV-infected B cells., PMID:35472072
Estrogen induces the expression of EBV lytic protein ZEBRA, a marker of poor prognosis in nasopharyngeal carcinoma., PMID:35633182
LMP1 Induces p53 Protein Expression via the H19/miR-675-5p Axis., PMID:35674441
Maintenance of Epstein-Barr virus latency through interaction of LMP2A with CXCR4., PMID:35752684
Andrographolide Inhibits Epstein-Barr Virus Lytic Reactivation in EBV-Positive Cancer Cell Lines through the Modulation of Epigenetic-Related Proteins., PMID:35889536
IFI16 Partners with KAP1 to Maintain Epstein-Barr Virus Latency., PMID:35969079
Rapid antibody responses to Epstein-Barr virus correlate with reduced severity of primary infection., PMID:36007460
High Predictive Value of the Soluble ZEBRA Antigen (Epstein-Barr Virus Trans-Activator Zta) in Transplant Patients with PTLD., PMID:36015048
MC180295 Inhibited Epstein-Barr Virus-Associated Gastric Carcinoma Cell Growth by Suppressing DNA Repair and the Cell Cycle., PMID:36142506
Rta is the principal activator of Epstein-Barr virus epithelial lytic transcription., PMID:36174106
An in-silico insight into the predictive interaction of Apolipoprotein-E with Epstein-Barr virus proteins and their probable role in mediating Alzheimer's disease., PMID:36307908
EBV infection mediated BDNF expression is associated with bladder inflammation in interstitial cystitis/bladder pain syndrome with Hunner's lesion., PMID:36441149
HLA-E-restricted immune responses are crucial for the control of EBV infections and the prevention of PTLD., PMID:36477802
Epstein-Barr Virus Synergizes with BRD7 to Conquer c-Myc-Mediated Viral Latency Maintenance via Chromatin Remodeling., PMID:36728436
Epstein‒Barr virus and human herpesvirus 6 infection in patients with systemic lupus erythematosus., PMID:36782252
Evaluation of host cellular responses to Epstein-Barr virus (EBV) in adult lung transplant patients with EBV-associated diseases., PMID:37185866
Changes in SUMO-modified proteins in Epstein-Barr virus infection identifies reciprocal regulation of TRIM24/28/33 complexes and the lytic switch BZLF1., PMID:37410772
Upregulation of IQGAP2 by EBV transactivator Rta and its influence on EBV life cycle., PMID:37504571
A library-derived peptide inhibitor of the BZLF1 transcription factor., PMID:38041527
A distinct isoform of lymphoid enhancer binding factor 1 (LEF1) epigenetically restricts EBV reactivation to maintain viral latency., PMID:38113273
Construction of rBCG carrying the IL-2-BZLF1 fusion gene and its immunological function., PMID:38170315
Ceramide promotes lytic reactivation of Epstein-Barr virus in gastric carcinoma., PMID:38197630
Differential carbonic anhydrase activities control EBV-induced B-cell transformation and lytic cycle reactivation., PMID:38530845
Synthetic BZLF1-targeted transcriptional activator for efficient lytic induction therapy against EBV-associated epithelial cancers., PMID:38702330
Lytic and Latent Genetic Diversity of the Epstein-Barr Virus Reveals Raji-Related Variants from Southeastern Brazil Associated with Recombination Markers., PMID:38732219
The nucleic acid binding protein SFPQ represses EBV lytic reactivation by promoting histone H1 expression., PMID:38755141
Evaluation of novel Epstein-Barr virus-derived antigen formulations for monitoring virus-specific T cells in pediatric patients with infectious mononucleosis., PMID:38877590
Multiplex assays reveal anti-EBV antibody profile and its implication in detection and diagnosis of nasopharyngeal carcinoma., PMID:38894502
Gene profiling of Epstein-Barr Virus and human endogenous retrovirus in peripheral blood mononuclear cells of SLE patients: immune response implications., PMID:39215087
Epstein-Barr virus replication within differentiated epithelia requires pRb sequestration of activator E2F transcription factors., PMID:39291960
TianTan vaccinia virus-based EBV vaccines targeting both latent and lytic antigens elicits potent immunity against lethal EBV challenge in humanized mice., PMID:39387189
Reactivation of Epstein-Barr virus by n-butyric acid from Pseudoramibacter alactolyticus induces inflammatory cytokines in periapical granulomas., PMID:39401546
Ubiquitin-Mediated Effects on Oncogenesis during EBV and KSHV Infection., PMID:39459858
Entry into the lytic cycle exposes EBV-infected cells to NK cell killing via upregulation of the MICB ligand for NKG2D and activation of the CD56bright and NKG2A+KIR+CD56dim subsets., PMID:39676862
Computational biology assisted exploration of phytochemicals derived natural inhibitors to block BZLF1 gene activation of Epstein-Bar virus in host., PMID:39738195
In-depth analysis of serum antibodies against Epstein-Barr virus lifecycle proteins, and EBNA1, ANO2, GlialCAM and CRYAB peptides in patients with multiple sclerosis., PMID:39742283
Interpreting the role of epigallocatechin-3-gallate in Epstein-Barr virus infection-mediated neuronal diseases., PMID:39849283
Epstein-Barr virus hijacks histone demethylase machinery to drive epithelial malignancy progression through KDM5B upregulation., PMID:40059116
A Comparative Genomic Analysis of Epstein-Barr Virus Strains with a Focus on EBV2 Variability., PMID:40141350
Heat shock factor 2 regulates oncogenic gamma-herpesvirus gene expression by remodeling the chromatin at the ORF50 and BZLF1 promoter., PMID:40245053
Influence of DNA Sequences on the Thermodynamic and Structural Stability of the ZTA Transcription Factor─DNA Complex: An All-Atom Molecular Dynamics Study., PMID:40266646
Leveraging the interconnected unfolded protein response and NLRP3 inflammasome pathways to reactivate Epstein-Barr virus in diffuse large B-cell lymphomas., PMID:40330549
Hsa-miR-7974 Suppresses Epstein-Barr Virus Reactivation by Directly Targeting BZLF1 and BRLF1., PMID:40431607
EBV Reactivation-associated gene signature predicts poor prognosis in nasopharyngeal carcinoma., PMID:40457434
Anti-EBV: Artificial intelligence driven predictive modeling for repurposing drugs as potential antivirals against Epstein-Barr virus., PMID:40458637
Inhibitory effect of recombinant BCG containing the fusion gene BFNA on EB virus-positive tumors., PMID:40459582
Dihydrotestosterone-androgen receptor signaling suppresses EBV-positive gastric cancer through DNA demethylation-mediated viral reactivation., PMID:40504439
For research use only. Not for human or drug use.
