Catalog No.
YXX21901
Expression system
E. coli
Species
Streptococcus pneumoniae
Protein length
Gln23-Leu413
Predicted molecular weight
44.11 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
WP_061743357.1
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
D-alanyl-D-alanine carboxypeptidase PBP3, pbp3
Repurposing of drugs against bacterial infections: A pharmacovigilance-based data mining approach., PMID:38807372
Peptidoglycan biosynthesis-associated enzymatic kinetic characteristics and β-lactam antibiotic inhibitory effects of different Streptococcus pneumoniae penicillin-binding proteins., PMID:37949278
Ceftobiprole medocaril for the treatment of pneumonia., PMID:37042813
Non-steroidal anti-inflammatory drugs ketorolac and etodolac can augment the treatment against pneumococcal meningitis by targeting penicillin-binding proteins., PMID:35921951
Expanded profiling of β-lactam selectivity for penicillin-binding proteins in Streptococcus pneumoniae D39., PMID:35218689
β-Lactam Resistance in Upper Respiratory Tract Pathogens Isolated from a Tertiary Hospital in Malaysia., PMID:34959557
Antibiotic-Induced Cell Chaining Triggers Pneumococcal Competence by Reshaping Quorum Sensing to Autocrine-Like Signaling., PMID:30485808
Promoter Identification and Transcription Analysis of Penicillin-Binding Protein Genes in Streptococcus pneumoniae R6., PMID:27409661
Distinctive Binding of Avibactam to Penicillin-Binding Proteins of Gram-Negative and Gram-Positive Bacteria., PMID:26574008
Profiling of β-lactam selectivity for penicillin-binding proteins in Streptococcus pneumoniae D39., PMID:25845878
Substrate specificity of low-molecular mass bacterial DD-peptidases., PMID:22029692
Absence of pneumococcal PcsB is associated with overexpression of LysM domain-containing proteins., PMID:21474534
Mechanisms, molecular and sero-epidemiology of antimicrobial resistance in bacterial respiratory pathogens isolated from Japanese children., PMID:17697316
Binding of ceftobiprole and comparators to the penicillin-binding proteins of Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, and Streptococcus pneumoniae., PMID:17470659
Crystal structure of a peptidoglycan synthesis regulatory factor (PBP3) from Streptococcus pneumoniae., PMID:15596446
Genotyping of Streptococcus pneumoniae and Haemophilus influenzae isolated from paired middle ear fluid and nasopharynx by pulsed-field gel electrophoresis., PMID:15583436
Complete sequences of six penicillin-binding protein genes from 40 Streptococcus pneumoniae clinical isolates collected in Japan., PMID:15155228
The D,D-carboxypeptidase PBP3 organizes the division process of Streptococcus pneumoniae., PMID:15009891
Target affinities of faropenem to and its impact on the morphology of gram-positive and gram-negative bacteria., PMID:12886052
A review of the antimicrobial activity of clavulanate., PMID:12775671
Modulation of release of proinflammatory bacterial compounds by antibacterials: potential impact on course of inflammation and outcome in sepsis and meningitis., PMID:11781269
Differential functionalities of amphiphilic peptide segments of the cell-septation penicillin-binding protein 3 of Escherichia coli., PMID:10972821
Molecular characterization of a mutation affecting the amount of Streptococcus pneumoniae penicillin-binding protein 3., PMID:9270995
A mutation in the D,D-carboxypeptidase penicillin-binding protein 3 of Streptococcus pneumoniae contributes to cefotaxime resistance of the laboratory mutant C604., PMID:9145848
The non-penicillin-binding module of the tripartite penicillin-binding protein 3 of Escherichia coli is required for folding and/or stability of the penicillin-binding module and the membrane-anchoring module confers cell septation activity on the folded structure., PMID:8808928
The in-vitro activity of cefpodoxime: a comparison with other oral cephalosporins., PMID:2351624
Nucleotide sequences of the pbpX genes encoding the penicillin-binding proteins 2x from Streptococcus pneumoniae R6 and a cefotaxime-resistant mutant, C506., PMID:2615650
Cefmenoxime (SCE-1365), a novel broad-spectrum cephalosporin: in vitro and in vivo antibacterial activities., PMID:6941742