Catalog No.
YXX21706
Expression system
E. coli
Species
Streptococcus pyogenes
Protein length
Gly1-Glu100
Predicted molecular weight
12.53 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9R3A1
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
M protein, M1 protein
Structure-Based Classification of CRISPR/Cas9 Proteins: A Machine Learning Approach to Elucidating Cas9 Allostery., PMID:40291704
Post-pandemic upsurge in Group A Streptococcus infections at an Italian tertiary university hospital., PMID:40135916
Characteristics of Streptococcus pyogenes causing invasive infections among adults in Portugal, 2016-2019: Pre-COVID-19 expansion of the M1UK sublineage., PMID:40021403
Epitope Mapping with Sidewinder: An XL-MS and Structural Modeling Approach., PMID:40003954
Streptococcus pyogenes emm Type 3.93 Emergence, the Netherlands and England., PMID:39983683
Streptococcus pyogenes bloodstream infections in an Italian hospital: A ten-year genomic picture., PMID:39955886
Comparison of pharyngeal and invasive isolates of Streptococcus pyogenes by whole-genome sequencing in Toronto, Canada., PMID:39945517
Characterization of a novel covS SNP identified in Australian group A Streptococcus isolates derived from the M1UK lineage., PMID:39688411
Genomic epidemiology of invasive Group A Streptococcus infections in Argentina, 2023: high prevalence of emm1-global and detection of emm1 hypervirulent lineages., PMID:39611833
Clinical and microbiological characterization of invasive group a Streptococcus infection in children in Japan: A single-center experience., PMID:39549831
M proteins of group A Streptococcus bind hyaluronic acid via arginine-arginine/serine-arginine motifs., PMID:39436142
Inhibition of Macrophage Recruitment to Heart Valves Mediated by the C-C Chemokine Receptor Type 2 Attenuates Valvular Inflammation Induced by Group A Streptococcus in Lewis Rats., PMID:39206918
Nationwide upsurge in invasive disease in the context of longitudinal surveillance of carriage and invasive Streptococcus pyogenes 2009-2023, the Netherlands: a molecular epidemiological study., PMID:39194268
Molecular characterization of Streptococcus pyogenes (StrepA) non-invasive isolates during the 2022-2023 UK upsurge., PMID:39133528
[Prevalence of the M1UK sublineage among emm1 Streptococcus pyogenes invasive strains isolated in the Czech Republic from December 2022 to May 2023]., PMID:39060098
Divergent effects of emm types 1 and 12 on invasive group A streptococcal infections-results of a retrospective cohort study, Germany 2023., PMID:38990040
Rapid expansion and international spread of M1UK in the post-pandemic UK upsurge of Streptococcus pyogenes., PMID:38729927
Disruption of IL-17-mediated immunosurveillance in the respiratory mucosa results in invasive Streptococcus pyogenes infection., PMID:38576622
M1UKStreptococcus pyogenes causing community-acquired pneumonia, pleural empyema and streptococcal toxic shock syndrome., PMID:38552876
Quantification of Adaptive Immune Responses Against Protein-Binding Interfaces in the Streptococcal M1 Protein., PMID:38527648
Group A streptococcal collagen-like protein 1 restricts tumor growth in murine pancreatic adenocarcinoma and inhibits cancer-promoting neutrophil extracellular traps., PMID:38515758
Clinical, microbiological, and molecular characterization of pediatric invasive infections by Streptococcus pyogenes in Spain in a context of global outbreak., PMID:38440985
Detection of toxigenic M1UK lineage group A Streptococcus clones in Taiwan., PMID:38278671
Epidemiological changes in invasive Streptococcus pyogenes infection during the UK alert period: A molecular comparative analysis from a tertiary Spanish hospital in 2023., PMID:38176845
Characterization of the RofA regulon in the pandemic M1global and emergent M1UK lineages of Streptococcus pyogenes., PMID:38117674
Effect of Nk-lysin peptides on bacterial growth, MIC, antimicrobial resistance, and viral activities., PMID:38100547
Population of invasive group A streptococci isolates from a German tertiary care center is dominated by the hypertoxigenic virulent M1UK genotype., PMID:38064158
Insertion of an immunodominant T helper cell epitope within the Group A Streptococcus M protein promotes an IFN-γ-dependent shift from a non-protective to a protective immune response., PMID:37654501
Slipped-strand mispairing within a polycytidine tract in transcriptional regulator mga leads to M protein phase variation and Mga length polymorphism in Group A Streptococcus., PMID:37434706
Elucidation of independently modulated genes in Streptococcus pyogenes reveals carbon sources that control its expression of hemolytic toxins., PMID:37278526
Streptococcus pyogenes Colonization in Children Aged 24-59 Months in the Gambia: Impact of Live Attenuated Influenza Vaccine and Associated Serological Responses., PMID:37246259
Phenotypic Characterization of Acoustically Enriched Extracellular Vesicles from Pathogen-Activated Platelets., PMID:37245510
Role of serotype and virulence determinants of Streptococcus pyogenes biofilm bacteria in internalization and persistence in epithelial cells in vitro., PMID:37234777
Characterization of emergent toxigenic M1UK Streptococcus pyogenes and associated sublineages., PMID:37093716
Emerging Invasive Group A Streptococcus M1UK Lineage Detected by Allele-Specific PCR, England, 20201., PMID:37019153
Pseudouridimycin-A Potent Nucleoside Inhibitor of the RNA Polymerase Beta Prime Subunit of Streptococcus pyogenes., PMID:36873015
Detection of Streptococcus pyogenes M1UK in Australia and characterization of the mutation driving enhanced expression of superantigen SpeA., PMID:36828918
Characterization of M-Type-Specific Pilus Expression in Group A Streptococcus., PMID:36286511
The effects of air pollutants exposure on the transmission and severity of invasive infection caused by an opportunistic pathogen Streptococcus pyogenes., PMID:35932897
RPS5A Promoter-Driven Cas9 Produces Heritable Virus-Induced Genome Editing in Nicotiana attenuata., PMID:34963106
Distinct Serotypes of Streptococcal M Proteins Mediate Fibrinogen-Dependent Platelet Activation and Proinflammatory Effects., PMID:34898252
Attenuation of virulence in multiple serotypes (M1, M3, and M28) of Group A Streptococcus after the loss of secreted esterase., PMID:34674958
Streptococcal protein SIC activates monocytes and induces inflammation., PMID:33855284
Structural determination of Streptococcus pyogenes M1 protein interactions with human immunoglobulin G using integrative structural biology., PMID:33411763
A naturally occurring point mutation in the rocA gene of Streptococcus pyogenes confers the highly virulent phenotype., PMID:33309630
Cross-serotype protection against group A Streptococcal infections induced by immunization with SPy_2191., PMID:32669564
Integrin α5β1, as a Receptor of Fibronectin, Binds the FbaA Protein of Group A Streptococcus To Initiate Autophagy during Infection., PMID:32518187
Streptococcus pyogenes genes that promote pharyngitis in primates., PMID:32493846
[Invasive Streptococcus pyogenes infections (2011-2018): EMM-type and clinical presentation]., PMID:31879253
Cold Atmospheric Plasma Disarms M1 Protein, an Important Streptococcal Virulence Factor., PMID:31563899
For research use only. Not for human or drug use.
