Catalog No.
PMJ18201
Species reactivity
Mouse
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Mouse TICAM1 (Gln394-His510).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
TIR domain-containing adapter molecule 1, TICAM-1, Toll-interleukin-1 receptor domain-containing adapter protein inducing interferon beta, TIR domain-containing adapter protein inducing IFN-beta, Ticam1, Trif
Purification
Purified by antigen affinity column.
Accession
Q80UF7
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
ARNAX is an ideal adjuvant for COVID-19 vaccines to enhance antigen-specific CD4+ and CD8+ T-cell responses and neutralizing antibody induction., PMID:40231823
Key roles for phosphorylation and the Coiled-coil domain in TRIM56-mediated positive regulation of TLR3-TRIF-dependent innate immunity., PMID:38556084
Immunofluorescent Labeling in Nasal Mucosa Tissue Sections of Allergic Rhinitis Rats via Multicolor Immunoassay., PMID:37811950
Successful treatment of acute encephalitis and hepatitis in a child with COVID-19 infection., PMID:36610889
Lipopolysaccharide from biofilm-forming Pseudomonas aeruginosa PAO1 induces macrophage hyperinflammatory responses., PMID:33909550
New insights in acetaminophen toxicity: HMGB1 contributes by itself to amplify hepatocyte necrosis in vitro through the TLR4-TRIF-RIPK3 axis., PMID:32221312
CD14 Counterregulates Lipopolysacharide-Induced Tumor Necrosis Factor-α Production in a Macrophage Subset., PMID:30654377
Coculture with bone marrow‑derived mesenchymal stem cells attenuates inflammation and apoptosis in lipopolysaccharide‑stimulated alveolar epithelial cells via enhanced secretion of keratinocyte growth factor and angiopoietin‑1 modulating the Toll‑like receptor‑4 signal pathway., PMID:30628710
Engagement of Fas differentially regulates the production of LPS-induced proinflammatory cytokines and type I interferons., PMID:30536547
Rhinovirus 3C protease suppresses apoptosis and triggers caspase-independent cell death., PMID:29449668
Dysregulation of miR-155-5p and miR-200-3p and the Anti-Non-Bilayer Phospholipid Arrangement Antibodies Favor the Development of Lupus in Three Novel Murine Lupus Models., PMID:29349090
The inhibition of MyD88 and TRIF signaling serve equivalent roles in attenuating myocardial deterioration due to acute severe inflammation., PMID:29115392
Toll-like receptor 3 in nasal CD103+ dendritic cells is involved in immunoglobulin A production., PMID:28612840
A TLR3-Specific Adjuvant Relieves Innate Resistance to PD-L1 Blockade without Cytokine Toxicity in Tumor Vaccine Immunotherapy., PMID:28564605
Down regulation of TRIF, TLR3, and MAVS in HCV infected liver correlates with the outcome of infection., PMID:28480979
Differential Regulation of TLR Signaling on the Induction of Antiviral Interferons in Human Intestinal Epithelial Cells Infected with Enterovirus 71., PMID:27007979
Monophosphoryl lipid A-induced pro-inflammatory cytokine expression does not require CD14 in primary human dendritic cells., PMID:26994069
CD200Fc reduces TLR4-mediated inflammatory responses in LPS-induced rat primary microglial cells via inhibition of the NF-κB pathway., PMID:26956766
Down-regulation of TLR2, 3, 9 and Signaling Mediators, MyD88 and TRIF, Gene Transcript Levels in Patients with Kawasaki Disease Treated with IVIG., PMID:25780885
Heme oxygenase-1 protects rat liver against warm ischemia/reperfusion injury via TLR2/TLR4-triggered signaling pathways., PMID:25780291
The attenuated inflammation of MPL is due to the lack of CD14-dependent tight dimerization of the TLR4/MD2 complex at the plasma membrane., PMID:24380872
SHPS-1 and a synthetic peptide representing its ITIM inhibit the MyD88, but not TRIF, pathway of TLR signaling through activation of SHP and PI3K in THP-1 cells., PMID:23314616
Brucella β 1,2 cyclic glucan is an activator of human and mouse dendritic cells., PMID:23166489
Anti-β(2)GPI/β(2)GPI induced TF and TNF-α expression in monocytes involving both TLR4/MyD88 and TLR4/TRIF signaling pathways., PMID:22964479
[The activation of TRIF-dependent signaling pathway in THP-1 cells induced by β₂ GPI/anti-β₂ GPI antibodies complex]., PMID:22152804
CD300a and CD300f differentially regulate the MyD88 and TRIF-mediated TLR signalling pathways through activation of SHP-1 and/or SHP-2 in human monocytic cell lines., PMID:22043923
Involvement of TNFα-induced TLR4-NF-κB and TLR4-HIF-1α feed-forward loops in the regulation of inflammatory responses in glioma., PMID:21887505
CD300F blocks both MyD88 and TRIF-mediated TLR signaling through activation of Src homology region 2 domain-containing phosphatase 1., PMID:21536801
The role of polymorphisms in Toll-like receptors and their associated intracellular signaling genes in measles vaccine immunity., PMID:21424379
Antiviral responses induced by the TLR3 pathway., PMID:21312311
Immunomodulatory effects of polysaccharopeptide (PSP) in human PBMC through regulation of TRAF6/TLR immunosignal-transduction pathways., PMID:20131955
Association of interacting genes in the toll-like receptor signaling pathway and the antibody response to pertussis vaccination., PMID:18987746
Inflammation and autoimmunity caused by a SHP1 mutation depend on IL-1, MyD88, and a microbial trigger., PMID:18806225
Viral double-stranded RNA triggers Ig class switching by activating upper respiratory mucosa B cells through an innate TLR3 pathway involving BAFF., PMID:18566393
Increased expression of Toll-like receptor 3 in intrahepatic biliary epithelial cells at sites of ductular reaction in diseased livers., PMID:19669308
Toll-like receptors., PMID:18432983
For research use only. Not for human or drug use.
