Anti-Mouse RANBP2 Polyclonal Antibody

Catalog No.

PME74301

Species reactivity

Mouse

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Mouse RANBP2 (Tyr1840-Ala2000).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

E3 SUMO-protein ligase RanBP2, 2.3.2.-, Ran-binding protein 2, RanBP2, Ranbp2

Purification

Purified by antigen affinity column.

Accession

Q9ERU9

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Parvimonas micra promotes oral squamous cell carcinoma metastasis through TmpC-CKAP4 axis., PMID:40055343

Glia maturation factor-γ regulates amyloid-β42 phagocytosis through scavenger receptor class A type I in murine macrophages., PMID:39243388

Antibody-assisted selective isolation of Purkinje cell nuclei from mouse cerebellar tissue., PMID:38981474

Defining the Clinicoradiologic Syndrome of SARS-CoV-2 Acute Necrotizing Encephalopathy: A Systematic Review and 3 New Pediatric Cases., PMID:38086061

Recurrent acute hemorrhagic necrotizing encephalopathy associated with RAN-binding protein-2 gene mutation in a pediatric patient., PMID:36632547

COVID-19 related acute necrotizing encephalopathy with extremely high interleukin-6 and RANBP2 mutation in a patient with recently immunized inactivated virus vaccine and no pulmonary involvement., PMID:35870896

Incidence of paediatric multiple sclerosis and other acquired demyelinating syndromes: 10-year follow-up surveillance study., PMID:34693523

Radiological manifestation of familial acute necrotizing encephalopathy with RANBP2 mutation in a Far-East Asian family: Case report., PMID:33761695

Endogenously expressed Ranbp2 is not at the axon initial segment., PMID:33536249

A Novel Mechanism for NF-κB-activation via IκB-aggregation: Implications for Hepatic Mallory-Denk-Body Induced Inflammation., PMID:32912968

CD30 and ALK combination therapy has high therapeutic potency in RANBP2-ALK-rearranged epithelioid inflammatory myofibroblastic sarcoma., PMID:32684628

Diagnostic utility of pan-Trk immunohistochemistry for inflammatory myofibroblastic tumours., PMID:31578734

Acute Hemorrhagic Encephalitis Responding to Combined Decompressive Craniectomy, Intravenous Immunoglobulin, and Corticosteroid Therapies: Association with Novel RANBP2 Variant., PMID:29593631

In Vitro SUMOylation Assay to Study SUMO E3 Ligase Activity., PMID:29443041

Impairments in age-dependent ubiquitin proteostasis and structural integrity of selective neurons by uncoupling Ran GTPase from the Ran-binding domain 3 of Ranbp2 and identification of novel mitochondrial isoforms of ubiquitin-conjugating enzyme E2I (ubc9) and Ranbp2., PMID:28877029

An autoimmune myositis-overlap syndrome associated with autoantibodies to nuclear pore complexes: description and long-term follow-up of the anti-Nup syndrome., PMID:25500708

Nuclear translocation of IGF-1R via p150(Glued) and an importin-β/RanBP2-dependent pathway in cancer cells., PMID:24909165

Importin 7 and Nup358 promote nuclear import of the protein component of human telomerase., PMID:24586428

Immunoproteomics Identification of Major IgE and IgG4 Reactive Schistosoma japonicum Adult Worm Antigens Using Chronically Infected Human Plasma., PMID:23264728

Importin-β negatively regulates multiple aspects of mitosis including RANGAP1 recruitment to kinetochores., PMID:22331847

Immunomodulatory therapy in recurrent acute necrotizing encephalopathy ANE1: is it useful?, PMID:21945312

Bicaudal D2, dynein, and kinesin-1 associate with nuclear pore complexes and regulate centrosome and nuclear positioning during mitotic entry., PMID:20386726

"ChopNSpice," a mass spectrometric approach that allows identification of endogenous small ubiquitin-like modifier-conjugated peptides., PMID:19721078

SAGE analysis highlights the importance of p53csv, ddx5, mapkapk2 and ranbp2 to multiple myeloma tumorigenesis., PMID:19171422

Nuclear pore composition and gating in herpes simplex virus-infected cells., PMID:18562518

Regulation of Wnt signaling by the nuclear pore complex., PMID:18439914

The Nup358-RanGAP complex is required for efficient importin alpha/beta-dependent nuclear import., PMID:18305100

Nuclear envelope breakdown is coordinated by both Nup358/RanBP2 and Nup153, two nucleoporins with zinc finger modules., PMID:16314393

Nuclear transport of single molecules: dwell times at the nuclear pore complex., PMID:15657394

Nup358 integrates nuclear envelope breakdown with kinetochore assembly., PMID:12963708

The cytoplasmic filaments of the nuclear pore complex are dispensable for selective nuclear protein import., PMID:12105182

Analysis of the antibody repertoire of astrocytoma patients against antigens expressed by gliomas., PMID:11857388

The nucleoporin RanBP2 has SUMO1 E3 ligase activity., PMID:11792325

Perturbation of SUMOlation enzyme Ubc9 by distinct domain within nucleoporin RanBP2/Nup358., PMID:11709548

RanBP2 associates with Ubc9p and a modified form of RanGAP1., PMID:9108047

Identification of protein p270/Tpr as a constitutive component of the nuclear pore complex-attached intranuclear filaments., PMID:9024684

A small ubiquitin-related polypeptide involved in targeting RanGAP1 to nuclear pore complex protein RanBP2., PMID:9019411

Direct and indirect association of the small GTPase ran with nuclear pore proteins and soluble transport factors: studies in Xenopus laevis egg extracts., PMID:8885229

Localization of the Ran-GTP binding protein RanBP2 at the cytoplasmic side of the nuclear pore complex., PMID:8603673

A giant nucleopore protein that binds Ran/TC4., PMID:7603572

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