Catalog No.
PHJ84301
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human NOD1 (Ala612-Asp826).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
NOD1,Nucleotide-binding oligomerization domain-containing protein 1,Caspase recruitment domain-containing protein 4,CARD4
Purification
Purified by antigen affinity column.
Accession
Q9Y239
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
The immune system in cardiovascular diseases: from basic mechanisms to therapeutic implications., PMID:40404619
NOD1 signaling regulates early tissue inflammation during helminth infection., PMID:39662675
NOD1 Agonist Induces Proliferation and Plasma Cell Differentiation of Mouse B Cells Especially CD23high B Cells., PMID:39560184
The adjuvant effect of polymuramil, a NOD1 and NOD2 agonist, differs when immunizing mice of different inbred lines with nonstructural hepatitis C virus (Flaviviridae: Hepacivirus)proteins and is synergistically enhanced in combination with pyrogenalum, a TLR4 agonist., PMID:38156588
Effect of glutamine on the systemic innate immune response in broiler chickens challenged with Salmonella pullorum., PMID:38102601
Inhibition of Bacterial Peptidoglycan Cytopathy by Retina Pigment Epithelial PGRP2 Amidase., PMID:37440081
From Co-Infections to Autoimmune Disease via Hyperactivated Innate Immunity: COVID-19 Autoimmune Coagulopathies, Autoimmune Myocarditis and Multisystem Inflammatory Syndrome in Children., PMID:36769320
Sera of Neuromyelitis Optica Patients Increase BID-Mediated Apoptosis in Astrocytes., PMID:35806122
Nucleotide oligomerization domain polymorphism confers no risk to Guillain-Barré syndrome., PMID:35652365
Blockade of T cell activation induced by the simultaneous absence of Nod1 and Nod2 is bypassed by TLR2 signals., PMID:33706865
Uncoupling of invasive bacterial mucosal immunogenicity from pathogenicity., PMID:32332737
High-Concentrate Feeding to Dairy Cows Induces Apoptosis via the NOD1/Caspase-8 Pathway in Mammary Epithelial Cells., PMID:31963403
Nanoscale Coordination Polymer Based Nanovaccine for Tumor Immunotherapy., PMID:31710460
The regenerating family member 3 β instigates IL-17A-mediated neutrophil recruitment downstream of NOD1/2 signalling for controlling colonisation resistance independently of microbiota community structure., PMID:30279238
Nanoconjugation of bicistronic DNA vaccine against Edwardsiella tarda using chitosan nanoparticles: Evaluation of its protective efficacy and immune modulatory effects in Labeo rohita vaccinated by different delivery routes., PMID:29544687
NLR Nod1 signaling promotes survival of BCR-engaged mature B cells through up-regulated Nod1 as a positive outcome., PMID:28878001
Nonpyrogenic Molecular Adjuvants Based on norAbu-Muramyldipeptide and norAbu-Glucosaminyl Muramyldipeptide: Synthesis, Molecular Mechanisms of Action, and Biological Activities in Vitro and in Vivo., PMID:28829599
Activation of NOD-1/JNK/IL-8 signal axis in decidual stromal cells facilitates trophoblast invasion., PMID:28328096
Functional Toll-Like Receptor 9 Expression and CXCR3 Ligand Release in Pulmonary Sarcoidosis., PMID:27390897
Lactobacillus rhamnosus GR-1 Ameliorates Escherichia coli-Induced Inflammation and Cell Damage via Attenuation of ASC-Independent NLRP3 Inflammasome Activation., PMID:26655757
Directing vaccine immune responses to mucosa by nanosized particulate carriers encapsulating NOD ligands., PMID:26539801
Adhesion of monocytes to periodontal fibroblasts requires activation of NOD1/2- and TLR4-mediated LFA-1 and VLA-4., PMID:25791323
Intestinal microbiota diversity and expression of pattern recognition receptors in newly weaned piglets., PMID:25528290
Recognition of Coxiella burnetii by toll-like receptors and nucleotide-binding oligomerization domain-like receptors., PMID:25246533
Functional characterization of receptor-interacting serine/threonine kinase 2 (RIP2) of the goldfish (Carassius auratus L.)., PMID:25242011
The cofilin phosphatase slingshot homolog 1 (SSH1) links NOD1 signaling to actin remodeling., PMID:25187968
Aggregatibacter actinomycetemcomitans outer membrane vesicles are internalized in human host cells and trigger NOD1- and NOD2-dependent NF-κB activation., PMID:25024364
Immune responses to Helicobacter pylori infection., PMID:24914318
Nucleotide oligomerization domain 1 ligation suppressed murine allergen-specific T-cell proliferation and airway hyperresponsiveness., PMID:24279792
Expression of inflammatory genes in the colon of ulcerative colitis patients varies with activity both at the mRNA and protein level., PMID:24197332
Helicobacter pylori cag pathogenicity island (cagPAI) involved in bacterial internalization and IL-8 induced responses via NOD1- and MyD88-dependent mechanisms in human biliary epithelial cells., PMID:24143223
Increased expression of pattern recognition receptors and nitric oxide synthase in patients with endometriosis., PMID:23935397
Allergy to betalactams and nucleotide-binding oligomerization domain (NOD) gene polymorphisms., PMID:23888881
The CARD8 p.C10X mutation associates with a low anti-glycans antibody response in patients with Crohn's disease., PMID:23506543
Encapsulation of Nod1 and Nod2 receptor ligands into poly(lactic acid) nanoparticles potentiates their immune properties., PMID:23352911
The interplay between the gut immune system and microbiota in health and disease: nutraceutical intervention for restoring intestinal homeostasis., PMID:23151182
Role of NOD1-mediated signals in a mouse model of allergic rhinitis., PMID:23032918
Peptidoglycan and muramyl dipeptide from Staphylococcus aureus induce the expression of VEGF-A in human limbal fibroblasts with the participation of TLR2-NFκB and NOD2-EGFR., PMID:22890731
MDP up-regulates the gene expression of type I interferons in human aortic endothelial cells., PMID:22447023
Expression of pattern recognition receptors in liver biopsy specimens of children chronically infected with HBV and HCV., PMID:22038219
Nucleotide oligomerization domain-containing proteins instruct T cell helper type 2 immunity through stromal activation., PMID:21856952
A TLR2 agonist is a more effective adjuvant for a Chlamydia major outer membrane protein vaccine than ligands to other TLR and NOD receptors., PMID:21742006
Variants of NOD1 and NOD2 genes display opposite associations with familial risk of Crohn's disease and anti-saccharomyces cerevisiae antibody levels., PMID:21739538
TLR-9, NOD-1, NOD-2, RIG-I and immunoglobulins in recurrent otitis media with effusion., PMID:20980062
Polymorphisms of innate pattern recognition receptors, response to interferon-beta and development of neutralizing antibodies in multiple sclerosis patients., PMID:20595247
TLR-related pathway analysis: novel gene-gene interactions in the development of asthma and atopy., PMID:19968634
Nod1/Nod2-mediated recognition plays a critical role in induction of adaptive immunity to anthrax after aerosol exposure., PMID:19620350
PR3-ANCA in Wegener's granulomatosis prime human mononuclear cells for enhanced activation via TLRs and NOD1/2., PMID:19594951
A function for AAMP in Nod2-mediated NF-kappaB activation., PMID:19535145
Familial aggregation and antimicrobial response dose-dependently affect the risk for Crohn's disease., PMID:19504613
For research use only. Not for human or drug use.
