Catalog No.
YMF01201
Expression system
E. coli
Species
Mus musculus (Mouse)
Protein length
Met195-Arg254
Predicted molecular weight
34.84 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P53986
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Monocarboxylate transporter 1, MCT 1, Solute carrier family 16 member 1, Slc16a1, Mct1
Transmembrane Protease Serine 11B Modulates Lactate Transport Through SLC16A1 in Pancreatic Ductal Adenocarcinoma-A Functional Link to Phenotype Heterogeneity., PMID:40508207
Ion Channel-Extracellular Matrix Interplay in Colorectal Cancer: A Network-Based Approach to Tumor Microenvironment Remodeling., PMID:40507957
The lactylation-immune regulatory axis: a potential therapeutic target for migraine prevention and treatment., PMID:40468199
SLC16A1 Inhibits Ferroptosis and Promotes the Progression of Head and Neck Squamous Cell Carcinoma., PMID:40302798
Exploring the Molecular Intersection of Posterior Ocular Tuberculosis: Mycobacterium tuberculosis Proteins, Ocular Autoimmunity, and Immune Receptor Interactions., PMID:40151358
Lactate metabolic coupling between the endplates and nucleus pulposus via MCT1 is essential for intervertebral disc health., PMID:40060488
Lactate dehydrogenase B deficiency-dependent hyperlactatemia coordinates with necroptosis to worsen septic liver and kidney injuries., PMID:40043615
Structural and molecular dysfunctions in granulosa cells: A key contributor to porcine follicular atresia., PMID:40043493
Lactate metabolism in clonal plasma cells and its therapeutic implications in multiple myeloma patients with elevated serum LDH levels., PMID:39948621
Identification of the immune infiltration and biomarkers in ulcerative colitis based on liquid-liquid phase separation-related genes., PMID:39915583
Association Between Genetically Proxied SLC12A2 Inhibition and Inflammatory Bowel Disease: A Mendelian Randomization Study., PMID:39913044
The association of SLC16A1 (MCT1) gene polymorphism with body composition changes during weight loss interventions: A randomized trial with sex-dependent analysis., PMID:39787575
Hypoglycaemia following physical exercise in a patient with novel SLC16A1 variant., PMID:39715334
Genetic and non-genetic factors influencing the therapeutic response of valproic acid in pediatric epileptic patients., PMID:39711059
Isolation method of brain microvessels from small frozen human brain tissue for blood-brain barrier protein expression analysis., PMID:39702171
LncRNA SLC16A1-AS1 participates in the initiation and progression of colorectal cancer by regulating MAP3K9 expression through targeting miR-515-5p., PMID:39659936
YTHDF1 boosts the lactate accumulation to potentiate cervical cancer cells immune escape., PMID:39557826
Regulatory Role of eIF2αK4 in Amino Acid Transporter Expression in Mouse Brain Capillary Endothelial Cells., PMID:39532778
Transcriptome-scale RNA-targeting CRISPR screens reveal essential lncRNAs in human cells., PMID:39532094
Exploring the anticancer mechanism of cardiac glycosides using proteome integral solubility alteration approach., PMID:39350574
Comprehensive transcriptome analysis unravels the perturbated cardiovascular-related molecular mechanisms of tilapia under high-temperature stress., PMID:39298880
Exosomal SLC16A1-AS1-induced M2 macrophages polarization facilitates hepatocellular carcinoma progression., PMID:39247822
ITCH inhibits alkaliptosis in human pancreatic cancer cells through YAP1-dependent SLC16A1 activation., PMID:39179170
Renshen Yangrong decoction for secondary malaise and fatigue: network pharmacology and Mendelian randomization study., PMID:38966421
Exosomal circSIPA1L3-mediated intercellular communication contributes to glucose metabolic reprogramming and progression of triple negative breast cancer., PMID:38849860
Novel lactylation-related signature to predict prognosis for pancreatic adenocarcinoma., PMID:38817665
Transporter Protein Expression of Corneal Epithelium in Rabbit and Porcine: Evaluation of Models for Ocular Drug Transport Study., PMID:38809137
lncRNA CDKN2B-AS1 is downregulated in patients with ventricular fibrillation in acute myocardial infarction., PMID:38771854
The Pivotal Function of SLC16A1 and SLC16A1-AS1 in Cancer Progress: Molecular Pathogenesis and Prognosis., PMID:38616756
Enhancing the anticancer effect of androgen deprivation therapy by monocarboxylate transporter 1 inhibitor in prostate cancer cells., PMID:38558458
Targeting Metabolic Dependencies Fueling the TCA Cycle to Circumvent Therapy Resistance in Acute Myeloid Leukemia., PMID:38558131
Oncogenic circ-SLC16A1 promotes progression of non-small cell lung cancer via regulation of the miR-1287-5p/profilin 2 axis., PMID:38539084
Metabolic pathways of glucose and fructose: II Spatiotemporal expression of genes involved in synthesis and transport of lactate in ovine conceptuses†., PMID:38531778
The polymorphism T1470A of the SLC16A1 gene is associated with the lactate and ventilatory thresholds but not with fat oxidation capacity in young men., PMID:38216723
A systemic analysis of monocarboxylate transporters in ovarian cancer and possible therapeutic interventions., PMID:37934721
Upregulation of BMP1 through ncRNAs correlates with adverse outcomes and immune infiltration in clear cell renal cell carcinoma., PMID:37848987
Differential expression of mRNA 3'-end isoforms in cervical and ovarian cancers., PMID:37810050
Dysfunctional Cori and Krebs cycle and inhibition of lactate transporters constitute a mechanism of primary nonfunction of fatty liver allografts., PMID:37722450
Paralog-dependent isogenic cell assay cascade generates highly selective SLC16A3 inhibitors., PMID:37516113
Expression analysis of BACH1 with clinical variables using the US breast cancer patient cohort., PMID:37461502
Development of a method for isolating brain capillaries from a single neonatal mouse brain and comparison of proteomic profiles between neonatal and adult brain capillaries., PMID:37353852
A novel mutation in the KCNJ11 gene (p.Val36Glu), predisposes to congenital hyperinsulinemia., PMID:37336273
Construction of SLC16A1/3 Targeted Gallic Acid-Iron-Embelin Nanoparticles for Regulating Glycolysis and Redox Pathways in Cervical Cancer., PMID:37307591
Differential effect of lactate on synovial fibroblast and macrophage effector functions., PMID:37304267
Interlaboratory Variability in the Madin-Darby Canine Kidney Cell Proteome., PMID:37283406
Prognostic Value of Monocarboxylate Transporter 1 Overexpression in Cancer: A Systematic Review., PMID:36982217
Monocarboxylate transporter 1 in the liver modulates high-fat diet-induced obesity and hepatic steatosis in mice., PMID:36933792
Comprehensive analysis of pan-cancer reveals the potential of SLC16A1 as a prognostic and immunological biomarker., PMID:36930112
The hsa_circ_0000276-ceRNA regulatory network and immune infiltration in cervical cancer., PMID:36894874
Interaction between Butyrate and Tumor Necrosis Factor α in Primary Rat Colonocytes., PMID:36830627
For research use only. Not for human or drug use.
