Catalog No.
YME54201
Expression system
E. coli
Species
Mus musculus (Mouse)
Protein length
Ser30-Gly114
Predicted molecular weight
37.44 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P47993
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Lymphotactin, C motif chemokine 1, Cytokine SCM-1, Lymphotaxin, Small-inducible cytokine C1, Xcl1, Lptn, Ltn, Scyc1
The XCL1/XCR1 axis is upregulated in type 1 diabetes and aggravates its pathogenesis., PMID:40014407
Associations between plasma proteins and psychological wellbeing: evidence from over 20 years of the English Longitudinal Study of Ageing., PMID:39974132
Systemic trafficking of macrophages in implant wear debris-induced periprosthetic osteolysis., PMID:39914493
Cardiovascular Risk Biomarkers in Women with and Without Polycystic Ovary Syndrome., PMID:39858399
Developing an Effective Therapeutic HPV Vaccine to Eradicate Large Tumors by Genetically Fusing Xcl1 and Incorporating IL-9 as Molecular Adjuvants., PMID:39852828
The XCL1-XCR1 axis supports intestinal tissue residency and antitumor immunity., PMID:39841133
The multifaceted role of XCL1 in health and disease., PMID:39840812
Trabectedin Enhances the Antitumor Effects of IL-12 in Triple-Negative Breast Cancer., PMID:39777457
XCL1-secreting CEA CAR-T cells enhance endogenous CD8+ T cell responses to tumor neoantigens to confer a long-term antitumor immunity., PMID:39762074
Targeting CD206+ macrophages disrupts the establishment of a key antitumor immune axis., PMID:39601781
Molecular basis for chemokine recognition and activation of XCR1., PMID:39565315
The integrated molecular and histological analysis defines subtypes of esophageal squamous cell carcinoma., PMID:39419971
Bacillus amyloliquefaciens TL promotes gut health of broilers by the contribution of bacterial extracellular polysaccharides through its anti-inflammatory potential., PMID:39376562
Use of optimized single-cell RNA flow cytometry protocol identifies monocytes as main producers of type I interferon in mouse syngeneic tumors., PMID:39372774
The Role of Chemokines in Obesity and Exercise-Induced Weight Loss., PMID:39334887
Neutralizing IL-38 activates γδ T cell-dependent antitumor immunity and sensitizes for chemotherapy., PMID:39209451
Hinesol attenuates DSS-induced ulcerative colitis through the suppression of Src-mediated NF-κB and chemokine signaling pathway., PMID:38976102
Chemokines and Cytokines in Immunotherapy of Melanoma and Other Tumors: From Biomarkers to Therapeutic Targets., PMID:38928238
The interplay between birth weight and obesity in determining childhood and adolescent cardiometabolic risk., PMID:38918147
Inflammatory response in traumatic brain and spinal cord injury: The role of XCL1-XCR1 axis and T cells., PMID:38887195
Targeting BCL9/BCL9L enhances antigen presentation by promoting conventional type 1 dendritic cell (cDC1) activation and tumor infiltration., PMID:38811552
B-cell-directed CAR T-cell therapy activates CD8+ cytotoxic CARneg bystander T cells in patients and nonhuman primates., PMID:38558106
TIGIT Blockade Reshapes the Tumor Microenvironment Based on the Single-cell RNA-Sequencing Analysis., PMID:38545758
The chemokine XCL1 functions as a pregnancy hormone to program offspring innate anxiety., PMID:38428650
Intratumoral delivery of a highly active form of XCL1 enhances antitumor CTL responses through recruitment of CXCL9-expressing conventional type-1 dendritic cells., PMID:38346928
The XCL1-Mediated DNA Vaccine Targeting Type 1 Conventional Dendritic Cells Combined with Gemcitabine and Anti-PD1 Antibody Induces Potent Antitumor Immunity in a Mouse Lung Cancer Model., PMID:38339158
Different Transcriptome Features of Peripheral Blood Mononuclear Cells in Non-Emphysematous Chronic Obstructive Pulmonary Disease., PMID:38203236
Tox induces T cell IL-10 production in a BATF-dependent manner., PMID:38054003
Large chemokine binding spectrum of human and mouse atypical chemokine receptor GPR182 (ACKR5)., PMID:38026988
A candidate nanoparticle vaccine comprised of multiple epitopes of the African swine fever virus elicits a robust immune response., PMID:37964304
Critical role of CD206+ macrophages in promoting a cDC1-NK-CD8 T cell anti-tumor immune axis., PMID:37961697
Improvements in immune/melanocyte biomarkers with JAK3/TEC family kinase inhibitor ritlecitinib in vitiligo., PMID:37777018
Exploration of Key Immune-Related Transcriptomes Associated with Doxorubicin-Induced Cardiotoxicity in Patients with Breast Cancer., PMID:37684436
Early milk-feeding regimes in calves exert long-term effects on the development of ovarian granulosa cells., PMID:37626314
Targeting Members of the Chemokine Family as a Novel Approach to Treating Neuropathic Pain., PMID:37570736
XCR1 expression distinguishes human conventional dendritic cell type 1 with full effector functions from their immediate precursors., PMID:37566635
A novel predictive model for the recurrence of pediatric alopecia areata by bioinformatics analysis and a single-center prospective study., PMID:37359017
Crowded environments tune the fold-switching in metamorphic proteins., PMID:37291449
Metamorphic protein folding as evolutionary adaptation., PMID:37270322
Thermodynamic Evolution of a Metamorphic Protein: A Theoretical-Computational Study of Human Lymphotactin., PMID:37233895
Identification and validation of chemokine system-related genes in idiopathic pulmonary fibrosis., PMID:37122736
Integrating single-cell RNA sequencing with spatial transcriptomics reveals an immune landscape of human myometrium during labour., PMID:37095651
A chemokine network of T cell exhaustion and metabolic reprogramming in renal cell carcinoma., PMID:37006314
Lipocalin-2 deletion attenuates lipopolysaccharide-induced acute lung inflammation via downregulating chemotaxis-related genes., PMID:36806084
The Hub Genes Related to Osteoporosis Were Identified by Bioinformatics Analysis., PMID:36755691
IFNα and 5-Aza-2'-deoxycytidine combined with a dendritic-cell targeting DNA vaccine alter tumor immune cell infiltration in the B16F10 melanoma model., PMID:36741387
Hub Genes and Immune Cell Infiltration in Hypoxia-Induced Pulmonary Hypertension: Bioinformatics Analysis and In Vivo Validation., PMID:36718060
Ferrostatin-1 Inhibits Toll-Like Receptor 4/NF-κB Signaling to Alleviate Intervertebral Disc Degeneration in Rats., PMID:36690077
New insights into the analgesic properties of the XCL1/XCR1 and XCL1/ITGA9 axes modulation under neuropathic pain conditions - evidence from animal studies., PMID:36618360
XCL1, a serum biomarker in neurological diseases; HTLV-1-associated myelopathy and multiple sclerosis., PMID:36572194
For research use only. Not for human or drug use.
