Catalog No.
YHN51601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Thr314-Ser385
Predicted molecular weight
36.13 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
D6RGH6
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Multicilin, Multiciliate differentiation and DNA synthesis-associated cell cycle protein, McIdas protein, Protein Idas, MCIDAS, IDAS, MCI, MCIN
Disruption of GMNC-MCIDAS multiciliogenesis program is critical in choroid plexus carcinoma development., PMID:35322202
Bi-allelic mutations in MCIDAS and CCNO cause human infertility associated with abnormal gamete transport., PMID:34569065
Transcriptional regulation of multiciliated cell differentiation., PMID:32362381
Defects in efferent duct multiciliogenesis underlie male infertility in GEMC1-, MCIDAS- or CCNO-deficient mice., PMID:30936178
Mcidas mutant mice reveal a two-step process for the specification and differentiation of multiciliated cells in mammals., PMID:30877126
Distinct requirements of E2f4 versus E2f5 activity for multiciliated cell development in the zebrafish embryo., PMID:30218642
Multicilin and activated E2f4 induce multiciliated cell differentiation in primary fibroblasts., PMID:30120325
TRRAP is a central regulator of human multiciliated cell formation., PMID:29588376
Controlling centriole numbers: Geminin family members as master regulators of centriole amplification and multiciliogenesis., PMID:29243212
NEUROD2 Regulates Stim1 Expression and Store-Operated Calcium Entry in Cortical Neurons., PMID:28303257
The aryl hydrocarbon receptor controls cyclin O to promote epithelial multiciliogenesis., PMID:27554288
GemC1 controls multiciliogenesis in the airway epithelium., PMID:26882546
IL-13 Inhibits Multicilin Expression and Ciliogenesis via Janus Kinase/Signal Transducer and Activator of Transcription Independently of Notch Cleavage., PMID:26414872
Mcidas and GemC1 are key regulators for the generation of multiciliated ependymal cells in the adult neurogenic niche., PMID:26395491
MCIDAS mutations result in a mucociliary clearance disorder with reduced generation of multiple motile cilia., PMID:25048963
The Geminin and Idas coiled coils preferentially form a heterodimer that inhibits Geminin function in DNA replication licensing., PMID:24064211
Idas, a novel phylogenetically conserved geminin-related protein, binds to geminin and is required for cell cycle progression., PMID:21543332
For research use only. Not for human or drug use.
