Catalog No.
YHN51201
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gln23-Ala149
Predicted molecular weight
17.18 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
A6NGQ2
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Oocyte-expressed protein homolog, KH homology domain-containing protein 2, Oocyte- and embryo-specific protein 19, hOEP19, OOEP, C6orf156, KHDC2, OEP19
Cryo-EM structure of the human subcortical maternal complex and the associated discovery of infertility-associated variants., PMID:39379527
Variants in NLRP2 and ZFP36L2, non-core components of the human subcortical maternal complex, cause female infertility with embryonic development arrest., PMID:39178021
The maternal protein NLRP5 stabilizes UHRF1 in the cytoplasm: implication for the pathogenesis of multilocus imprinting disturbance., PMID:38868925
Revealing the expression profile of genes that encode the Subcortical Maternal Complex in human reproductive failures., PMID:38091268
NLRP7 participates in the human subcortical maternal complex and its variants cause female infertility characterized by early embryo arrest., PMID:37148315
Mutations in OOEP and NLRP5 identified in infertile patients with early embryonic arrest., PMID:35946397
Novel multilocus imprinting disturbances in a child with expressive language delay and intellectual disability., PMID:35365979
Trans-acting genetic variants causing multilocus imprinting disturbance (MLID): common mechanisms and consequences., PMID:35296332
Subcortical maternal complex (SCMC) expression during folliculogenesis is affected by oocyte donor age in sheep., PMID:32613414
The subcortical maternal complex protein Nlrp4f is involved in cytoplasmic lattice formation and organelle distribution., PMID:31575650
The pivotal roles of the NOD-like receptors with a PYD domain, NLRPs, in oocytes and early embryo development†., PMID:31201414
Proteomic analysis of mouse ovaries during the prepubertal stages., PMID:30797753
Maternal gene Ooep may participate in homologous recombination-mediated DNA double-strand break repair in mouse oocytes., PMID:29955025
Mouse embryonic stem cells have increased capacity for replication fork restart driven by the specific Filia-Floped protein complex., PMID:29125140
Identification of a human subcortical maternal complex., PMID:25542835
Expression of maternally derived KHDC3, NLRP5, OOEP and TLE6 is associated with oocyte developmental competence in the ovine species., PMID:25420964
The subcortical maternal complex controls symmetric division of mouse zygotes by regulating F-actin dynamics., PMID:25208553
Maternal-effect Floped gene is essential for the derivation of embryonic stem cells in mice., PMID:23776005
Dynamic changes in leptin distribution in the progression from ovum to blastocyst of the pre-implantation mouse embryo., PMID:21444625
Maternal-effect gene Ces5/Ooep/Moep19/Floped is essential for oocyte cytoplasmic lattice formation and embryonic development at the maternal-zygotic stage transition., PMID:20590823
Atypical structure and phylogenomic evolution of the new eutherian oocyte- and embryo-expressed KHDC1/DPPA5/ECAT1/OOEP gene family., PMID:17913455