Catalog No.
YHN49901
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Asp31-Ser138
Predicted molecular weight
40.36 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9NYZ3
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
G2 and S phase-expressed protein 1, GTSE-1, Protein B99 homolog, GTSE1
METTL16 accelerates lung adenocarcinoma progression by inducing N6-methyladenosine modification of GTSE1 to regulate p53 pathway and cell cycle., PMID:40405148
A comprehensive review and in silico analysis of the role of survivin (BIRC5) in hepatocellular carcinoma hallmarks: A step toward precision., PMID:40306500
Vitamin K2 mitigates cognitive, and motor impairments induced by multiple surgery with anesthesia and analgesia in neonatal stage., PMID:40273626
Stabilization of GTSE1 by cyclin D1-CDK4/6-mediated phosphorylation promotes cell proliferation with implications for cancer prognosis., PMID:40272409
Identification of MCM2-Interacting Proteins Associated with Replication Initiation Using APEX2-Based Proximity Labeling Technology., PMID:39940790
Comprehensive analysis of the diagnostic and therapeutic value, immune infiltration, and drug treatment mechanisms of GTSE1 in lung adenocarcinoma., PMID:39629227
An integrative lipidomics and transcriptomics study revealing Bavachin and Icariin synergistically induce idiosyncratic liver injury., PMID:39505304
GTSE1-driven ZEB1 stabilization promotes pulmonary fibrosis through the epithelial-to-mesenchymal transition., PMID:39342428
Engineered lipid nanoparticles enable therapeutic gene silencing of GTSE1 for the treatment of liver fibrosis., PMID:39154935
The Overexpression of NUSAP1 and GTSE1 Could Predict An Unfavourable Prognosis and Shorter Disease Free Survival in ccRenal Cell Carcinoma., PMID:39068590
[Relationship between GTSE1 and Cell Cycle and Potential Regulatory Mechanisms
in Lung Cancer Cells]., PMID:39026496
Stabilization of GTSE1 by cyclin D1-CDK4/6-mediated phosphorylation promotes cell proliferation: relevance in cancer prognosis., PMID:38979260
Novel cancer-fighting role of ticagrelor inhibits GTSE1-induced EMT by regulating PI3K/Akt/NF-κB signaling pathway in malignant glioma., PMID:38774096
GTSE1: A potential prognostic and diagnostic biomarker in various tumors including lung adenocarcinoma., PMID:38715380
G2 and S phase-expressed protein 1 is a biomarker for poor prognosis in lung adenocarcinoma., PMID:38518054
A Network of 17 Microtubule-Related Genes Highlights Functional Deregulations in Breast Cancer., PMID:37835564
Pan-cancer analyses reveal GTSE1 as a biomarker for the immunosuppressive tumor microenvironment., PMID:37653815
GTSE1 promotes the growth of NSCLC by regulating microtubule-associated proteins through the ERK/MAPK pathway., PMID:37079439
High GTSE1 expression promotes cell proliferation, metastasis and cisplatin resistance in ccRCC and is associated with immune infiltrates and poor prognosis., PMID:36999057
Identification of novel candidate genes and predicted miRNAs in atopic dermatitis patients by bioinformatic methods., PMID:36543921
Koumine induces apoptosis in Cyprinus carpio liver cells by regulating JAK-STAT and p53 signaling pathways., PMID:36496140
Transcription profiling of feline mammary carcinomas and derived cell lines reveals biomarkers and drug targets associated with metabolic and cell cycle pathways., PMID:36220861
CTPS1 inhibition suppresses proliferation and migration in colorectal cancer cells., PMID:35912542
Using Weighted Gene Co-Expression Network Analysis to Identify Increased MND1 Expression as a Predictor of Poor Breast Cancer Survival., PMID:35601002
UBE2T is a prognostic biomarker and correlated with Th2 cell infiltrates in retinoblastoma., PMID:35594577
GTSE1 promotes tumor growth and metastasis by attenuating of KLF4 expression in clear cell renal cell carcinoma., PMID:35585131
GTSE1 is possibly involved in the DNA damage repair and cisplatin resistance in osteosarcoma., PMID:34876170
Identification of miRNAs and genes for predicting Barrett's esophagus progressing to esophageal adenocarcinoma using miRNA-mRNA integrated analysis., PMID:34818353
Discovery and construction of prognostic model for clear cell renal cell carcinoma based on single-cell and bulk transcriptome analysis., PMID:34733651
Identifying key genes and screening therapeutic agents associated with diabetes mellitus and HCV-related hepatocellular carcinoma by bioinformatics analysis., PMID:34588861
Downregulation of GTSE1 leads to the inhibition of proliferation, migration, and Warburg effect in cervical cancer by blocking LHDA expression., PMID:34482592
STK35L1 regulates host cell cycle-related genes and is essential for Plasmodium infection during the liver stage of malaria., PMID:34358525
MiR-509-3-5p inhibits colon cancer malignancy by suppressing GTSE1., PMID:34284144
Single-cell transcriptome analysis of human oocyte ageing., PMID:34037315
GTSE1 Facilitates the Malignant Phenotype of Lung Cancer Cells via Activating AKT/mTOR Signaling., PMID:34007784
G2 and S phase-expressed-1 acts as a putative tumor promoter in cervical cancer by enhancing Wnt/β-catenin signaling via modulation of GSK-3β., PMID:33974332
GTSE1 promotes SNAIL1 degradation by facilitating its nuclear export in hepatocellular carcin oma cells., PMID:33880590
Identification of potential and novel target genes in pituitary prolactinoma by bioinformatics analysis., PMID:33709028
A rare case of paediatric astroblastoma with concomitant MN1-GTSE1 and EWSR1-PATZ1 gene fusions altering management., PMID:33534137
Defining endogenous TACC3-chTOG-clathrin-GTSE1 interactions at the mitotic spindle using induced relocalization., PMID:33380489
Destabilization of Long Astral Microtubules via Cdk1-Dependent Removal of GTSE1 from Their Plus Ends Facilitates Prometaphase Spindle Orientation., PMID:33333009
GTSE1 promotes prostate cancer cell proliferation via the SP1/FOXM1 signaling pathway., PMID:33328578
Identification of G2 and S Phase-Expressed-1 as a Potential Biomarker in Patients with Prostate Cancer., PMID:33061616
Sensitivity to differential NRF1 gene signatures contributes to breast cancer disparities., PMID:32705365
lncRNA LINC00665 Stabilized by TAF15 Impeded the Malignant Biological Behaviors of Glioma Cells via STAU1-Mediated mRNA Degradation., PMID:32464546
Knockdown GTSE1 enhances radiosensitivity in non-small-cell lung cancer through DNA damage repair pathway., PMID:32202046
GTSE1, CDC20, PCNA, and MCM6 Synergistically Affect Regulations in Cell Cycle and Indicate Poor Prognosis in Liver Cancer., PMID:32082966
Clathrin's adaptor interaction sites are repurposed to stabilize microtubules during mitosis., PMID:31932847
Transcriptome Analyses of the Anti-Proliferative Effects of 20(S)-Ginsenoside Rh2 on HepG2 Cells., PMID:31780945
DNA Damage and Repair in Patients With Coronary Artery Disease: Correlation With Plaque Morphology Using Optical Coherence Tomography (DECODE Study)., PMID:31178349
For research use only. Not for human or drug use.
