Catalog No.
YHN48001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
His173-Arg266
Predicted molecular weight
25.17 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9UHK0
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
FMR1-interacting protein NUFIP1, Nuclear FMR1-interacting protein 1, Nuclear FMRP-interacting protein 1, NUFIP1
Features and mechanisms of long-lived Myotis somatic fibroblasts in response to DNA replication stress., PMID:40407135
Rpl12 is a conserved ribophagy receptor., PMID:39934334
NUFIP1 integrates amino acid sensing and DNA damage response to maintain the intestinal homeostasis., PMID:39753713
Targeted proteomics addresses selectivity and complexity of protein degradation by autophagy., PMID:39245437
Order/Disorder Transitions Upon Protein Binding: A Unifying Perspective., PMID:39158131
NUFIP1-engineered exosomes derived from hUMSCs regulate apoptosis and neurological injury induced by propofol in newborn rats., PMID:38599287
PRKAA2, MTOR, and TFEB in the regulation of lysosomal damage response and autophagy., PMID:38183492
Nuclear fragile X mental retardation-interacting protein 1-mediated ribophagy protects T lymphocytes against apoptosis in sepsis., PMID:36873287
Percutaneous electrical stimulation-induced muscle contraction prevents the decrease in ribosome RNA and ribosome protein during pelvic hindlimb suspension., PMID:36007895
NUFIP1+ stroma keeps PDAC fed., PMID:35982180
Cancer-associated fibroblasts employ NUFIP1-dependent autophagy to secrete nucleosides and support pancreatic tumor growth., PMID:35982178
The Use of "Retardation" in FRAXA, FMRP, FMR1 and Other Designations., PMID:35326495
Structural Analysis of the Plasmodial Proteins ZNHIT3 and NUFIP1 Provides Insights into the Selectivity of a Conserved Interaction., PMID:35315277
13q Deletion Syndrome Involving RB1: Characterization of a New Minimal Critical Region for Psychomotor Delay., PMID:34573300
Targeting NUFIP1 Suppresses Growth and Induces Senescence of Colorectal Cancer Cells., PMID:34367967
Reduced rDNA transcription diminishes skeletal muscle ribosomal capacity and protein synthesis in cancer cachexia., PMID:33527503
Selective autophagy as a therapeutic target for neurological diseases., PMID:33067655
Organelle-specific autophagy in inflammatory diseases: a potential therapeutic target underlying the quality control of multiple organelles., PMID:32048886
The autophagic protein LC3 translocates to the nucleus and localizes in the nucleolus associated to NUFIP1 in response to cyclic mechanical stress., PMID:31476975
Identification and Characterization of Novel Fusion Genes with Potential Clinical Applications in Mexican Children with Acute Lymphoblastic Leukemia., PMID:31096545
Finding a ribophagy receptor., PMID:30067425
NUFIP1 is a ribosome receptor for starvation-induced ribophagy., PMID:29700228
Structural Features of the Box C/D snoRNP Pre-assembly Process Are Conserved through Species., PMID:27594683
Structure/Function Analysis of Protein-Protein Interactions Developed by the Yeast Pih1 Platform Protein and Its Partners in Box C/D snoRNP Assembly., PMID:26210662
Proteomic and 3D structure analyses highlight the C/D box snoRNP assembly mechanism and its control., PMID:25404746
Protein Hit1, a novel box C/D snoRNP assembly factor, controls cellular concentration of the scaffolding protein Rsa1 by direct interaction., PMID:25170085
Massively parallel sequencing reveals an accumulation of de novo mutations and an activating mutation of LPAR1 in a patient with metastatic neuroblastoma., PMID:24147068
Screening a genome-wide S. pombe deletion library identifies novel genes and pathways involved in genome stability maintenance., PMID:19264558
The Hsp90 chaperone controls the biogenesis of L7Ae RNPs through conserved machinery., PMID:18268104
A dynamic scaffold of pre-snoRNP factors facilitates human box C/D snoRNP assembly., PMID:17636026
Retinoblastoma and mental retardation microdeletion syndrome: clinical characterization and molecular dissection using array CGH., PMID:17502991
BRCA1 cooperates with NUFIP and P-TEFb to activate transcription by RNA polymerase II., PMID:15107825
NUFIP1 (nuclear FMRP interacting protein 1) is a nucleocytoplasmic shuttling protein associated with active synaptoneurosomes., PMID:12941608
Identification of mouse YB1/p50 as a component of the FMRP-associated mRNP particle., PMID:11162447
Assignment of NUFIP1 (nuclear FMRP interacting protein 1) gene to chromosome 13q14 and assignment of a pseudogene to chromosome 6q12., PMID:10894927
A novel RNA-binding nuclear protein that interacts with the fragile X mental retardation (FMR1) protein., PMID:10556305
For research use only. Not for human or drug use.
