Catalog No.
YHN47901
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Lys147
Predicted molecular weight
19.22 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9BTC8
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Metastasis-associated protein MTA3, MTA3, KIAA1266
Drug-likeness evaluation and inhibitory mechanism of the emodin derivative on cardiac fibrosis based on metastasis-associated protein 3., PMID:40083252
Targeting immune cellular populations and transcription factors: unraveling the therapeutic potential of JQF for NAFLD., PMID:39840059
Discovery of Jaspamycin from marine-derived natural product based on MTA3 to inhibit hepatocellular carcinoma progression., PMID:39455636
The feedback loop between MTA1 and MTA3/TRIM21 modulates stemness of breast cancer in response to estrogen., PMID:39154024
Metformin Prevents Tumor Cell Growth and Invasion of Human Hormone Receptor-Positive Breast Cancer (HR+ BC) Cells via FOXA1 Inhibition., PMID:39000600
Prognostic and immunological significance of metastasis-associated protein 3 in patients with thymic epithelial tumors., PMID:38852126
Function of TRPC1 in modulating hepatocellular carcinoma progression., PMID:36797544
Sphingosine kinase 1 promotes tumor immune evasion by regulating the MTA3-PD-L1 axis., PMID:36050478
[Corrigendum] High glucose promotes hepatic fibrosis via miR‑32/MTA3‑mediated epithelial‑to‑mesenchymal transition., PMID:36004471
Genome-wide CRISPR screen identifies MTA3 as an inducer of gemcitabine resistance in pancreatic ductal adenocarcinoma., PMID:35981571
lncRNA PCAT1 might coordinate ZNF217 to promote CRC adhesion and invasion through regulating MTA2/MTA3/Snai1/E-cadherin signaling., PMID:35809308
T2DM-elicited oxidative stress represses MTA3 expression in mouse Leydig cells., PMID:35239504
The effect of progesterone administration on the expression of metastasis tumor antigens (MTA1 and MTA3) in placentas of normal and dexamethasone-treated rats., PMID:35037193
Multi-omics analyses reveal the mechanisms of Arsenic-induced male reproductive toxicity in mice., PMID:34741939
Silver Nanoparticles Modulate the Epithelial-to-Mesenchymal Transition in Estrogen-Dependent Breast Cancer Cells In Vitro., PMID:34502112
Expression of Mug14 is regulated by the transcription factor Rst2 through the cAMP-dependent protein kinase pathway in Schizosaccharomyces pombe., PMID:34086083
Inhibition of MTA2 and MTA3 induces mesendoderm specification of human embryonic stem cells., PMID:33744762
CRISPRi enables isoform-specific loss-of-function screens and identification of gastric cancer-specific isoform dependencies., PMID:33499898
Human exome and mouse embryonic expression data implicate ZFHX3, TRPS1, and CHD7 in human esophageal atresia., PMID:32502225
Iron deficiency leads to repression of a non-canonical methionine salvage pathway in Schizosaccharomyces pombe., PMID:32090388
Bioinformatics analysis revealed hub genes and pathways involved in sorafenib resistance in hepatocellular carcinoma., PMID:31698564
Whole-genome resequencing analysis of Pengxian Yellow Chicken to identify genome-wide SNPs and signatures of selection., PMID:31656721
MTA3-SOX2 Module Regulates Cancer Stemness and Contributes to Clinical Outcomes of Tongue Carcinoma., PMID:31552166
Nuclear S-Nitrosylation Defines an Optimal Zone for Inducing Pluripotency., PMID:31412725
Emodin alleviates cardiac fibrosis by suppressing activation of cardiac fibroblasts via upregulating metastasis associated protein 3., PMID:31384533
Overexpression of circ_0021093 circular RNA forecasts an unfavorable prognosis and facilitates cell progression by targeting the miR-766-3p/MTA3 pathway in hepatocellular carcinoma., PMID:31330234
Layilin enhances the invasive ability of malignant glioma cells via SNAI1 signaling., PMID:31145904
Catalpol inhibits cell proliferation, invasion and migration through regulating miR-22-3p/MTA3 signalling in hepatocellular carcinoma., PMID:31145886
The Nucleosome Remodelling and Deacetylation complex suppresses transcriptional noise during lineage commitment., PMID:31036553
High glucose promotes hepatic fibrosis via miR‑32/MTA3‑mediated epithelial‑to‑mesenchymal transition., PMID:30816482
Long non-coding RNA HCG11 suppresses the growth of glioma by cooperating with the miR-4425/MTA3 axis., PMID:30706982
Novel TG-FGFR1 and TRIM33-NTRK1 transcript fusions in papillary thyroid carcinoma., PMID:30664823
Genome-wide meta-analysis identifies BARX1 and EML4-MTA3 as new loci associated with infantile hypertrophic pyloric stenosis., PMID:30281099
Bioinformatics analysis to screen for critical genes between survived and non‑survived patients with sepsis., PMID:30132542
Chromatin remodeling by the NuRD complex regulates development of follicular helper and regulatory T cells., PMID:29891681
Oroxyloside inhibits human glioma progression by suppressing proliferation, metastasis and inducing apoptosis related pathways., PMID:29793319
Bisphenol A-elicited miR-146a-5p impairs murine testicular steroidogenesis through negative regulation of Mta3 signaling., PMID:29746863
Correlation of metastasis-associated protein expression with prognosis and chemotherapy in nasopharyngeal carcinoma., PMID:31938367
The Homeotic Protein SIX3 Suppresses Carcinogenesis and Metastasis through Recruiting the LSD1/NuRD(MTA3) Complex., PMID:29463994
MiR-367 regulates cell proliferation and metastasis by targeting metastasis-associated protein 3 (MTA3) in clear-cell renal cell carcinoma., PMID:28968973
MTA3 Regulates Extravillous Trophoblast Invasion Through NuRD Complex., PMID:28959722
Metastasis-associated protein 3 in colorectal cancer determines tumor recurrence and prognosis., PMID:28418887
MTA3 regulates malignant progression of colorectal cancer through Wnt signaling pathway., PMID:28351306
Corepressor metastasis-associated protein 3 modulates epithelial-to-mesenchymal transition and metastasis., PMID:28279208
Current Molecular and Genetic Aspects of Pancreatic Cancer, the Role of Metastasis Associated Proteins (MTA): A Review., PMID:28060554
Immunohistochemical expression of MTA1 and MTA3 in placental tissue of normal and preeclamptic pregnancies., PMID:29949275
Overexpression of the metastasis-associated gene MTA3 correlates with tumor progression and poor prognosis in hepatocellular carcinoma., PMID:27992674
HIC1 (hypermethylated in cancer 1) SUMOylation is dispensable for DNA repair but is essential for the apoptotic DNA damage response (DDR) to irreparable DNA double-strand breaks (DSBs)., PMID:27935866
Dexamethasone-Induced Intrauterine Growth Restriction Is Associated With Altered Expressions of Metastasis Tumor Antigens and Cell Cycle Control Proteins in Rat Placentas., PMID:27932593
Regulated and Functional Expression of the Corepressor MTA3 in Rodent Testis., PMID:27673553
For research use only. Not for human or drug use.
