Catalog No.
YHJ74102
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ile54-Asn282
Predicted molecular weight
27.54 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9UBX7
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Kallikrein-11, hK11, 3.4.21.-, Hippostasin, Serine protease 20, Trypsin-like protease, Kallikrein-11 inactive chain 1, Kallikrein-11 inactive chain 2, KLK11, PRSS20, TLSP, UNQ649/PRO1279
Conserved structural topologies in RNase A-like and trypsin-like serine proteases: a sequence-based folding analysis., PMID:40437407
Divalent cations and SERPIN gene expression modulate horseshoe crab coagulation under LPS induction., PMID:40273978
Ovochymase 2 is a key regulatory factor modulating proteolytic pathways and sperm maturation in the mammalian epididymis., PMID:40155198
The structural characteristics and expression characteristics of C1S in response to GCRV infection in grass carp., PMID:40058677
miR-571 manipulating termite immune response to fungus and showing potential for green management of Copotermes formosanus (Blattodea: Isoptera)., PMID:40015866
KLK7 Involvement in Thyroid Papillary Carcinoma Cell Migration and Invasion by EMT via MAPK/ERK Pathways., PMID:39991575
KLK11-Related Disorder of Cornification Presenting as Inflammatory Skin Disease: A Familial Case Report and Literature Review., PMID:39902525
Circulating large extracellular vesicles as diagnostic biomarkers of indeterminate thyroid nodules: multi-platform omics analysis., PMID:39787026
Expressions of Immune Prophenoloxidase (proPO) System-Related Genes Under Oxidative Stress in the Gonads and Stomach of the Mud Crab (Macrophthalmus japonicus) Exposed to Endocrine-Disrupting Chemicals., PMID:39765762
A novel digestive protease chymotrypsin-like serine contributes to anti-BmNPV activity in silkworm (Bombyxmori)., PMID:39674304
Purification and Identification of the Nematicidal Activity of S1 Family Trypsin-Like Serine Protease (PRA1) from Trichoderma longibrachiatum T6 Through Prokaryotic Expression and Biological Function Assays., PMID:39596637
Structural Catalytic Core in Subtilisin-like Proteins and Its Comparison to Trypsin-like Serine Proteases and Alpha/Beta-Hydrolases., PMID:39595929
A sperm-activating trypsin-like protease from the male reproductive tract of Spodoptera litura: Proteomic identification, sequence characterization, gene expression profile, RNAi and the effects of ionizing radiation., PMID:38897288
YTHDF2 protein stabilization by the deubiquitinase OTUB1 promotes prostate cancer cell proliferation via PRSS8 mRNA degradation., PMID:38462165
KLK7, KLK10, and KLK11 in Papillary Thyroid Cancer: Bioinformatic Analysis and Experimental Validation., PMID:38316654
Serine protease mediates Ovomermis sinensis-inhibited host immune responses by inducing apoptosis: implications for successful parasitism and host mortality., PMID:38105114
Serum protein biomarkers for HCC risk prediction in HIV/HBV co-infected people: a clinical proteomic study using mass spectrometry., PMID:38022651
miR-1304 targets KLK11 to regulate gastric cancer cell proliferation through the mTOR signaling pathway., PMID:37971062
Composition characterization of various viperidae snake venoms using MS-based proteomics N-glycoproteomics and N-glycomics., PMID:37884129
Minireview: functional roles of tissue kallikrein, kinins, and kallikrein-related peptidases in lung cancer., PMID:37405520
Evaluation of the inhibitory potency of anti-dengue phytocompounds against DENV-2 NS2B-NS3 protease: virtual screening, ADMET profiling and molecular dynamics simulation investigations., PMID:37194462
Upregulation of KLK8 contributes to CUMS-induced hippocampal neuronal apoptosis by cleaving NCAM1., PMID:37076499
Mice deficient in synaptic protease neurotrypsin show impaired spaced long-term potentiation and blunted learning-induced modulation of dendritic spines., PMID:36871239
Variants in KLK11, affecting signal peptide cleavage of kallikrein-related peptidase 11, cause an autosomal-dominant cornification disorder., PMID:36689511
Kallikrein-Related Peptidase 6 (KLK6) as a Contributor toward an Aggressive Cancer Cell Phenotype: A Potential Role in Colon Cancer Peritoneal Metastasis., PMID:35883559
Aeromonas hydrophila Ssp1: A secretory serine protease that disrupts tight junction integrity and is essential for host infection., PMID:35798244
Cloning and functional analysis of a trypsin-like serine protease from Pinctada fucata martensii., PMID:35661766
Camostat Does Not Inhibit the Proteolytic Activity of Neutrophil Serine Proteases., PMID:35631327
In Silico Analysis Revealed Five Novel High-Risk Single-Nucleotide Polymorphisms (rs200384291, rs201163886, rs193141883, rs201139487, and rs201723157) in ELANE Gene Causing Autosomal Dominant Severe Congenital Neutropenia 1 and Cyclic Hematopoiesis., PMID:35571273
PRSS37 deficiency leads to impaired energy metabolism in testis and sperm revealed by DIA-based quantitative proteomic analysis., PMID:35471551
A systematic approach for evaluating the role of surface-exposed loops in trypsin-like serine proteases applied to the 170 loop in coagulation factor VIIa., PMID:35260627
A Novel Fibrinolytic Protein From Pheretima vulgaris: Purification, Identification, Antithrombotic Evaluation, and Mechanisms Investigation., PMID:35141276
Prospective evaluation of 92 serum protein biomarkers for early detection of ovarian cancer., PMID:35031764
Phenotypic responses and potential genetic mechanism of lepidopteran insects under exposure to graphene oxide., PMID:34808504
Kallikrein 11 Down-regulation in Breast Carcinoma: Correlation With Prognostic Parameters., PMID:34697154
KLK6 mediates stemness and metabolism of gastric carcinoma cells via the PI3K/AKT/mTOR signaling pathway., PMID:34691251
Antagonism of Protease Activated Receptor-2 by GB88 Reduces Inflammation Triggered by Protease Allergen Tyr-p3., PMID:34566947
Kallikrein-Related Peptidase 6 Is Associated with the Tumour Microenvironment of Pancreatic Ductal Adenocarcinoma., PMID:34439122
Hemagglutinins of Avian Influenza Viruses Are Proteolytically Activated by TMPRSS2 in Human and Murine Airway Cells., PMID:34319155
Identification of 13 Guanidinobenzoyl- or Aminidinobenzoyl-Containing Drugs to Potentially Inhibit TMPRSS2 for COVID-19 Treatment., PMID:34209110
Kallikrein-11, in Association with Coiled-Coil Domain Containing 25, as a Potential Prognostic Marker for Cholangiocarcinoma with Lymph Node Metastasis., PMID:34067437
KLK11 promotes the activation of mTOR and protein synthesis to facilitate cardiac hypertrophy., PMID:34059001
Screening of 5- and 6-Substituted Amiloride Libraries Identifies Dual-uPA/NHE1 Active and Single Target-Selective Inhibitors., PMID:33804289
Exposure of human intestinal epithelial cells and primary human hepatocytes to trypsin-like serine protease inhibitors with potential antiviral effect., PMID:33641565
Study on cocoonase, sericin, and degumming of silk cocoon: computational and experimental., PMID:33594479
KLK11 acts as a tumor-inhibitor in laryngeal squamous cell carcinoma through the inactivation of Akt/Wnt/β-catenin signaling., PMID:33420975
FAM111A induces nuclear dysfunction in disease and viral restriction., PMID:33369867
Bivalent antibody pliers inhibit β-tryptase by an allosteric mechanism dependent on the IgG hinge., PMID:33353951
A trypsin-like serine protease domain of masquerade gene in crayfish Procambarus clarkii could activate prophenoloxidase and inhibit bacterial growth., PMID:33340591
A novel serine protease inhibitor as potential treatment for dry eye syndrome and ocular inflammation., PMID:33057006
For research use only. Not for human or drug use.
