Catalog No.
YHJ17402
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ala23-Leu131
Predicted molecular weight
26.89 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q86YL7
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Podoplanin, Aggrus, Glycoprotein 36, Gp36, PA2.26 antigen, T1-alpha, T1A, 29kDa cytosolic podoplanin intracellular domain, PICD, PDPN, GP36, PSEC0003, PSEC0025
C-type lectin-like receptor 2 in platelets amplifies inflammation in rheumatoid arthritis., PMID:40486208
ITIH4 attenuates acute lung injury by Fe-containing particulate matter in mice via Hippo pathway in type II alveolar epithelial cells., PMID:40437524
Characterization of fibroblast-like synoviocytes from the synovial fluid of patients affected by juvenile idiopathic arthritis., PMID:40408229
Identification and Taste Characteristics of Six Novel Umami Peptides from Mytilus coruscus and Their Interaction with the T1R1/T1R3 Receptor., PMID:40384580
Treatment of Pancreatic Cancer Using Near-Infrared Photoimmunotherapy Targeting Cancer-Associated Fibroblasts in Combination with Anticancer Chemotherapeutic Drug., PMID:40361512
NETs activate AIM2 to mediate synovial fibroblast pyroptosis and promote acute gouty arthritis development., PMID:40267802
Lymphangiogenesis in the Deepest Invasive Areas of Human Early-Stage Colorectal Cancer., PMID:40243510
A proteogenomic tool uncovers protein markers for human microglial states., PMID:40236015
Cancer genetic profile and risk of thrombosis., PMID:40221227
Layer-specific molecular signatures of colon anastomotic healing and leakage in mice., PMID:40169980
Maackia amurensis seed lectin structure and sequence comparison with other M. amurensis lectins., PMID:40158854
The Supportive Role of Lymph Node Mesenchymal Stromal Cells in Follicular Lymphoma Involves the PITX1-hTERT-Podoplanin Axis., PMID:40130551
Serum Neurofilament Light Chain and Structural and Functional Nerve Fiber Loss in Painful and Painless Diabetic Polyneuropathy., PMID:40118191
Stromal Cell Subsets Show Model-Dependent Changes in Experimental Colitis and Affect Epithelial Tissue Repair and Immune Cell Activation., PMID:40100003
Charge matters: how flanking substrate charge modulates O-glycan Core elongation., PMID:40063838
Podoplanin-positive cell-derived small extracellular vesicles contribute to cardiac amyloidosis after myocardial infarction., PMID:40056419
Molecular Markers of Occult Lymph Node Metastasis in Head and Neck Squamous Cell Carcinoma (HNSCC) Patients., PMID:40018925
Lymphangioinvasion detection using the monoclonal antibody D2-40 (Podoplanin)as a clinical predictor of axillary lymph node metastasis in breast cancer patients., PMID:39988774
Comparative RNA-Seq analysis of differentially expressed genes in the sertoli cells of yak and cattle-yak., PMID:39987073
Protein expression of cancer stem cell markers ABCG2, podoplanin, and CD44 predicts early recurrence of oral squamous cell carcinoma: A study from Western India., PMID:39935327
ITGA5+ synovial fibroblasts orchestrate proinflammatory niche formation by remodelling the local immune microenvironment in rheumatoid arthritis., PMID:39919897
Knockdown of PDPN in astrocytes reduces hippocampal inflammation in T2DM mice., PMID:39911382
Molecular control of PDPNhi macrophage subset induction by ADAP as a host defense in sepsis., PMID:39903516
The C3/C3aR pathway exacerbates acetaminophen-induced mouse liver injury via upregulating podoplanin on the macrophage., PMID:39777689
The Patterns of P53, E-Cadherin, β-Catenin, CXCR4 and Podoplanin Expression in Oral Squamous Cell Carcinoma Suggests a Hybrid Invasion Model: an Immunohistochemical Study on Tissue Microarrays., PMID:39776043
Discovery of Carbonic Anhydrase 9 as a Novel CLEC2 Ligand in a Cellular Interactome Screen., PMID:39768175
PDPN+ cancer-associated fibroblasts enhance gastric cancer angiogenesis via AKT/NF-κB activation and the CCL2-ACKR1 axis., PMID:39764562
Lymphovascular Tumoral Emboli in Inflammatory Breast Cancer Result from Haptotaxis-Mediated Encircling Lymphangiogenesis., PMID:39669476
ROLE OF IMMUNOHISTOCHEMICAL EXPRESSION OF D2-40 MARKER IN HIGH-GRADE DYSPLASIA, MICROINVASIVE AND FRANKLY INVASIVE ORAL SQUAMOUS CELL CARCINOMA., PMID:39623817
Functional analysis of fibroblasts and macrophages in head and neck paragangliomas., PMID:39619326
PDPN/CLEC-2 axis modulates megakaryocyte subtypes in a hematopoietic stem cell-regulating megakaryocyte-dominant manner., PMID:39615442
Molecules That Have Rarely Been Studied in Lymphatic Endothelial Cells., PMID:39596293
A Cancer-Specific Anti-Podoplanin Monoclonal Antibody, PMab-117-mG2a Exerts Antitumor Activities in Human Tumor Xenograft Models., PMID:39594582
Depicting the cellular complexity of pancreatic adenocarcinoma by Imaging Mass Cytometry: focus on cancer-associated fibroblasts., PMID:39575252
Surfactant Protein-C Regulates Alveolar Type 2 Epithelial Cell Lineages via the CD74 Receptor., PMID:39553282
Structural changes in the nociceptive system induced by long-term conventional spinal cord stimulation in experimental painful diabetic polyneuropathy., PMID:39542640
Decoding lymphangiogenesis in oral squamous cell carcinoma: Emphasis on clinical and histopathological determinants of regional metastasis., PMID:39541328
VEGFC Overexpression in Kidney Progenitor Cells Is a Model of Renal Lymphangiectasia-Brief Report., PMID:39540281
CAF Specific Expression of Podoplanin May Be Dispensable for the Malignancy of Malignant Melanoma., PMID:39513649
Bidirectional signals generated by Siglec-7 and its crucial ligand tri-sialylated T to escape of cancer cells from immune surveillance., PMID:39507251
Lymphatic Vessels Accompanying Dorsal and Basal Dural Sinuses in the Human Brain., PMID:39492448
The prognostic implications of podoplanin in cancer-associated fibroblasts and PD-L1 expression in high-grade neuroendocrine carcinoma of the lung., PMID:39487962
Identification of Podoplanin Aptamers by SELEX for Protein Detection and Inhibition of Platelet Aggregation Stimulated by C-Type Lectin-like Receptor 2., PMID:39451677
Podoplanin Expression in Early-Stage Colorectal Cancer-Associated Fibroblasts and Its Utility as a Diagnostic Marker for Colorectal Lesions., PMID:39451200
Influence of Microenvironmental Orchestration on Multicellular Lung Alveolar Organoid Development from Human Induced Pluripotent Stem Cells., PMID:39417930
Identification of LRP1+CD13+ human periosteal stem cells that require LRP1 for bone repair., PMID:39405183
Effects of cadherin mediated contact normalization on oncogenic Src kinase mediated gene expression and protein phosphorylation., PMID:39397108
Podoplanin expressing macrophages and their involvement in tertiary lymphoid structures in mouse models of Sjögren's disease., PMID:39355243
Cancer-Associated Fibroblast Proteins as Potential Targets against Colorectal Cancers., PMID:39335130
Role of the serosa in intestinal anastomotic healing: insights from in-depth histological analysis of human and murine anastomoses., PMID:39230923