Catalog No.
YHH88001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
His302-Glu577
Predicted molecular weight
33.22 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q53FZ2
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Acyl-coenzyme A synthetase ACSM3, mitochondrial, 6.2.1.2, Acyl-CoA synthetase medium-chain family member 3, Butyrate--CoA ligase 3, Butyryl-coenzyme A synthetase 3, Middle-chain acyl-CoA synthetase 3, Propionate--CoA ligase, 6.2.1.17, Protein SA homolog, ACSM3, SAH
β-Hydroxybutyrate Reduces Body Weight by Modulating Fatty Acid Oxidation and Beiging in the Subcutaneous Adipose Tissue of DIO Mice., PMID:40507875
ACSM3 Suppresses Ovarian Cancer Progression by Inactivating the IFN-γ/JAK/STAT3 Signaling Pathway., PMID:39913127
Proteomics exploration of metformin hydrochloride for diabetic kidney disease treatment via the butanoate metabolism pathway., PMID:39615122
Delineation of renal protein profiles in aristolochic acid I-induced nephrotoxicity in mice by label-free quantitative proteomics., PMID:38783935
Comparative proteomic analysis of renal tissue of normotensive and hypertensive rats., PMID:38711408
ACSM1 and ACSM3 Regulate Fatty Acid Metabolism to Support Prostate Cancer Growth and Constrain Ferroptosis., PMID:38657108
Genetic alterations in the neuronal development genes are associated with changes of the tumor immune microenvironment in pancreatic cancer., PMID:38495381
Chewing the fat for good health: ACSM3 deficiency exacerbates metabolic syndrome., PMID:38263332
Liver ACSM3 deficiency mediates metabolic syndrome via a lauric acid-HNF4α-p38 MAPK axis., PMID:38191811
Quantitative proteomics analysis based on data-independent acquisition reveals the effect of Shenling Baizhu powder (SLP) on protein expression in MAFLD rat liver tissue., PMID:38036981
Acyl-CoA Medium-Chain Synthetase-3 (ACSM3) Is Regulated by Insulin Like Growth Factor 2 mRNA Binding Protein 3 (IGF2BP3) and Inhibits Proliferation, Motility and Stem Cell Properties of Breast Invasive Carcinoma., PMID:37625834
Integrative bioinformatics analysis of ACS enzymes as candidate prognostic and diagnostic biomarkers in colon adenocarcinoma., PMID:37614614
ACSM3 suppresses proliferation and induces apoptosis and cell cycle arrest in acute myeloid leukemia cells via the regulation of IGF2BP2., PMID:37006876
Melatonin Ameliorates Cisplatin-Induced Renal Tubular Epithelial Cell Damage through PPARα/FAO Regulation., PMID:36006825
Rutin-activated adipose tissue thermogenesis is correlated with increased intestinal short-chain fatty acid levels., PMID:35445769
Melatonin attenuates cisplatin-induced acute kidney injury in mice: Involvement of PPARα and fatty acid oxidation., PMID:35367536
THRSP identified as a potential hepatocellular carcinoma marker by integrated bioinformatics analysis and experimental validation., PMID:35196258
RNA-Seq reveals distinct transcriptomic differences in rotator cuff tendon based on tear etiology and patient sex., PMID:35174534
ACSM3 suppresses the pathogenesis of high-grade serous ovarian carcinoma via promoting AMPK activity., PMID:35124784
Acquisition of taxane resistance by p53 inactivation in ovarian cancer cells., PMID:35031699
The antioxidant tempol transforms gut microbiome to resist obesity in female C3H mice fed a high fat diet., PMID:34883252
Predicting Panel of Metabolism and Immune-Related Genes for the Prognosis of Human Ovarian Cancer., PMID:34322485
Hepatic Transcriptome Profiling Reveals Lack of Acsm3 Expression in Polydactylous Rats with High-Fat Diet-Induced Hypertriglyceridemia and Visceral Fat Accumulation., PMID:33923085
Loss of ACSM3 confers worsened prognosis and immune exclusion to cutaneous melanoma., PMID:33046979
Nephrotoxicity Profile of Cadmium Revealed by Proteomics in Mouse Kidney., PMID:32803525
Proteomic and cell biological profiling of the renal phenotype of the mdx-4cv mouse model of Duchenne muscular dystrophy., PMID:31776009
LSD1 mediates microbial metabolite butyrate-induced thermogenesis in brown and white adipose tissue., PMID:31734274
Hypolipidemic effect of novel 2,5-bis(4-hydroxybenzylidenamino)-1,3,4-thiadiazole as potential peroxisome proliferation-activated receptor-α agonist in acute hyperlipidemic rat model., PMID:30905023
Transcriptome of the Wistar audiogenic rat (WAR) strain following audiogenic seizures., PMID:30193173
Integrative transcriptome analysis of liver cancer profiles identifies upstream regulators and clinical significance of ACSM3 gene expression., PMID:28390038
High-fat diet decreases energy expenditure and expression of genes controlling lipid metabolism, mitochondrial function and skeletal system development in the adipose tissue, along with increased expression of extracellular matrix remodelling- and inflammation-related genes., PMID:25744306
Canonical correlation analysis for gene-based pleiotropy discovery., PMID:25329069
Adenosine dialdehyde suppresses MMP-9-mediated invasion of cancer cells by blocking the Ras/Raf-1/ERK/AP-1 signaling pathway., PMID:23994169
Impaired expression of genes involved in the butyrate oxidation pathway in Crohn's disease patients., PMID:22508661
Impaired butyrate oxidation in ulcerative colitis is due to decreased butyrate uptake and a defect in the oxidation pathway., PMID:21987487
Natural antisense transcript of natriuretic peptide precursor A (NPPA): structural organization and modulation of NPPA expression., PMID:19671135
Comparative analyses of disease risk genes belonging to the acyl-CoA synthetase medium-chain (ACSM) family in human liver and cell lines., PMID:19634011
Left ventricular structure in relation to the human SAH gene in the European Project on Genes in Hypertension., PMID:19262474
Human SA gene polymorphisms are associated with non-high-density lipoprotein cholesterol in postmenopausal women: a pilot study., PMID:19108963
Segmental renal sodium handling in relation to the human SAH gene., PMID:18519841
SAH gene variants revisited in the European Project On Genes in Hypertension., PMID:18192838
SAH gene variants are associated with obesity-related hypertension in Caucasians: the PEGASE Study., PMID:17278971
Exon repetition: a major pathway for processing mRNA of some genes is allele-specific., PMID:14739236
Overweight, but not hypertension, is associated with SAH polymorphisms in Caucasians with essential hypertension., PMID:14567496
Analysis of the role of the SA gene in blood pressure regulation by gene targeting., PMID:12707288
Role of genetic polymorphism in the SA gene on the blood pressure and prognosis of renal function in patients with immunoglobulin A nephropathy., PMID:12484505
[Specific antibodies for the early diagnosis of rheumatoid arthritis]., PMID:11798731
Molecular analysis of uromodulin and SAH genes, positional candidates for autosomal dominant medullary cystic kidney disease linked to 16p12., PMID:11730273
[The association between SA gene and essential hypertension in Han Chinese]., PMID:11592044
Genetic dissection of region around the Sa gene on rat chromosome 1: evidence for multiple loci affecting blood pressure., PMID:11509479
For research use only. Not for human or drug use.
