Catalog No.
YHG58701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Thr2-Asp356
Predicted molecular weight
55.55 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q13562
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Neurogenic differentiation factor 1, NeuroD, NeuroD1, Class A basic helix-loop-helix protein 3, bHLHa3, NEUROD1, BHLHA3, NEUROD
Transient islet-antigen 2 positivity at diagnosis of diabetes during COVID-19 infection in an adolescent with a NEUROD1 variant: a case report., PMID:40474235
NeuroD1 is frequently expressed in Merkel cell polyomavirus-negative and keratin 20-negative Merkel cell carcinoma: A potential diagnostic pitfall., PMID:40387007
NEUROD1 efficiently converts peripheral blood cells into neurons with partial reprogramming by pluripotency factors., PMID:40299704
Clinicopathological characteristics of transcription factor-defined subtypes in bladder small cell carcinoma., PMID:40275187
Challenges of small cell lung cancer heterogeneity and phenotypic plasticity., PMID:40211072
Identification of the core regulatory program driving NEUROD1-induced neuronal reprogramming., PMID:40173039
Prevalence and Clinical Characteristics of NEUROD1-MODY in Chinese Early-Onset Type 2 Diabetes Mellitus and a Literature Review., PMID:40148250
The expression order determines the pioneer functions of NGN3 and NEUROD1 in pancreatic endocrine differentiation., PMID:40138419
A case report of a MODY6 patient coexistence with Charcot-Marie-Toothe 1A syndrome., PMID:40026692
The Potential of Single-Transcription Factor Gene Expression by RT-qPCR for Subtyping Small Cell Lung Cancer., PMID:39941061
Molecular and Immunohistochemical Classification of Extrapulmonary Small Cell Neuroendocrine Carcinomas: A Study of 181 Cases., PMID:39826683
The analysis of molecular classification of pulmonary neuroendocrine tumors and relationship between YAP1 and efficacy., PMID:39786663
Comparison of molecular subtype composition between independent sets of primary and brain metastatic small cell lung carcinoma and matched samples., PMID:39721126
AAV Systems and Mouse Models for Investigating Ectopic Expression of Neurod1 in Transduced Cells at Subacute and Chronic Times Post-Ischemic Stroke., PMID:39671332
Hif-1α ablation reduces the efficiency of NeuroD1 gene-based therapy and aggravates the brain damage following ischemic stroke., PMID:39632618
Analysis of ASCL1/NEUROD1/POU2F3/YAP1 Yields Novel Insights for the Diagnosis of Olfactory Neuroblastoma and Identifies Sinonasal Tuft Cell-Like Carcinoma., PMID:39613231
Transcriptional coactivator MED15 is required for beta cell maturation., PMID:39379383
p300/CBP KATs Are Critical for Maturation and Differentiation of Adult Neural Progenitors., PMID:39317967
Neuroendocrine Differentiation in Prostate Cancer Requires ASCL1., PMID:39264686
A novel nonsense mutation c.747C>G in the NEUROD1 gene detected within a Chinese family affected by maturity-onset diabetes of the young type 6., PMID:39264012
Characteristics of molecular subtypes and cinical outcomes in the immunotherapy Queue of extensive-stage small cell lung cancer patients., PMID:39210380
Garlic Extract Promotes Pancreatic Islet Neogenesis Through α-to-β-Cell Transdifferentiation and Normalizes Glucose Homeostasis in Diabetic Rats., PMID:39205537
Jumonji histone demethylases are therapeutic targets in small cell lung cancer., PMID:39154123
Thyroid hormone suppresses medulloblastoma progression through promoting terminal differentiation of tumor cells., PMID:39137728
Leading medulloblastoma to a differentiation end., PMID:39137724
Neuronal repair after spinal cord injury by in vivo astrocyte reprogramming mediated by the overexpression of NeuroD1 and Neurogenin-2., PMID:39135103
Efficient Dlx2-mediated astrocyte-to-neuron conversion and inhibition of neuroinflammation by NeuroD1., PMID:39034481
In vivo neural regeneration via AAV-NeuroD1 gene delivery to astrocytes in neonatal hypoxic-ischemic brain injury., PMID:39014391
Differential NEUROD1, ASCL1, and POU2F3 Expression Defines Molecular Subsets of Bladder Small Cell/Neuroendocrine Carcinoma With Prognostic Implications., PMID:38964503
Reprogramming Glioblastoma Cells into Non-Cancerous Neuronal Cells as a Novel Anti-Cancer Strategy., PMID:38891029
Molecular subtypes of neuroendocrine carcinomas: A cross-tissue classification framework based on five transcriptional regulators., PMID:38788718
Transcription factor dynamics, oscillation, and functions in human enteroendocrine cell differentiation., PMID:38733993
Prognostic Implications of Small Cell Lung Cancer Transcriptional Subtyping for CNS Metastases., PMID:38691815
RFX4 is an intrinsic factor for neuronal differentiation through induction of proneural genes POU3F2 and NEUROD1., PMID:38386071
NeuroD1 Regulated Endothelial Gene Expression to Modulate Transduction of AAV-PHP.eB and Recovery Progress after Ischemic Stroke., PMID:38270116
Promoter-Specific Variants in NeuroD1 and H3K4me3 Coincident Regions and Clinical Outcomes of Small Cell Lung Cancer., PMID:37987107
Application of Small Cell Lung Cancer Molecular Subtyping Markers to Small Cell Neuroendocrine Carcinoma of the Cervix: NEUROD1 as a Poor Prognostic Factor., PMID:37981832
Photobiomodulation therapy enhances neural differentiation of dental pulp stem cells via ERK1/2 signaling pathway., PMID:37815161
Concordance of ASCL1, NEUROD1 and POU2F3 transcription factor-based subtype assignment in paired tumour samples from small cell lung carcinoma., PMID:37644667
Zebrafish pancreatic β cell clusters undergo stepwise regeneration using Neurod1-expressing cells from different cell lineages., PMID:37474621
Beta cell dysfunction induced by bone morphogenetic protein (BMP)-2 is associated with histone modifications and decreased NeuroD1 chromatin binding., PMID:37407581
Dynamic transition of molecular subtypes in relapsed small cell lung cancer treated with multimodal therapy: A case report., PMID:37253435
New AAV tools fail to detect Neurod1-mediated neuronal conversion of Müller glia and astrocytes in vivo., PMID:36947961
Genetic variants of NEUROD1 target genes are associated with clinical outcomes of small-cell lung cancer patients., PMID:36935366
Comparison of ASCL1, NEUROD1, and POU2F3 expression in surgically resected specimens, paired tissue microarrays, and lymph node metastases in small cell lung carcinoma., PMID:36715573
Neurod1 mediates the reprogramming of NG2 glial into neurons in vitro., PMID:36682427
Multimodal epigenetic changes and altered NEUROD1 chromatin binding in the mouse hippocampus underlie FOXG1 syndrome., PMID:36598943
Molecular features and evolutionary trajectory of ASCL1+ and NEUROD1+ SCLC cells., PMID:36517551
For research use only. Not for human or drug use.
