Catalog No.
YHF91701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gln468-Asp690
Predicted molecular weight
26.76 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q02108
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Guanylate cyclase soluble subunit alpha-1, GCS-alpha-1, 4.6.1.2, Guanylate cyclase soluble subunit alpha-3, GCS-alpha-3, Soluble guanylate cyclase large subunit, GUCY1A1, GUC1A3, GUCSA3, GUCY1A3
Soluble Guanylate Cyclase Dysfunction and Nitric Oxide Pathway in Chronic Rhinosinusitis With Nasal Polyps: Predictive Markers for Postoperative Recurrence., PMID:39473384
Preexisting senescent fibroblasts in the aged bladder create a tumor-permissive niche through CXCL12 secretion., PMID:39251867
Integrated single-cell and bulk RNA sequencing identifies POSTN as a potential biomarker and therapeutic target for rheumatoid arthritis., PMID:39067546
Metabolism-Related Prognostic Biomarkers, Purine Metabolism and Anti-Tumor Immunity in Colon Adenocarcinoma., PMID:38179743
Biallelic variants in NOS3 and GUCY1A3, the two major genes of the nitric oxide pathway, cause moyamoya cerebral angiopathy., PMID:36941667
FoxO4 controls sGCβ transcription in vascular smooth muscle., PMID:35089807
sGC Activity and Regulation of Blood Flow in a Zebrafish Model System., PMID:33716783
Novel ACE Inhibitory Peptides Derived from Yeast Hydrolysates: Screening, Inhibition Mechanisms and Effects on HUVECs., PMID:33593053
Higher susceptibility to heme oxidation and lower protein stability of the rare α1C517Yβ1 sGC variant associated with moyamoya syndrome., PMID:33571505
Moyamoya Disease 6 with Achalasia Due to GUCY1A3 Mutation in a Child., PMID:33109895
Associations between GUCY1A3 genetic polymorphisms and large artery atherosclerotic stroke risk in Chinese Han population: a case-control study., PMID:31883534
Soluble guanylyl cyclase α1 subunit is a key mediator of proliferation, survival, and migration in ECC-1 and HeLa cell lines., PMID:31616026
Variability in aspirin efficacy: all in the genes?, PMID:31280284
Genetic variation at the coronary artery disease risk locus GUCY1A3 modifies cardiovascular disease prevention effects of aspirin., PMID:31228190
Genetic influences on aspirin response in patients undergoing percutaneous coronary intervention., PMID:31049556
Association of the coronary artery disease risk gene GUCY1A3 with ischaemic events after coronary intervention., PMID:30768153
Differential expression of alternative transcripts of soluble guanylyl cyclase, GYCY1a3 and GUCY1b3 genes, in the malignant and benign breast tumors., PMID:30597209
Mechanical pressure unloading therapy reverses thoracic aortic structural and functional changes in a hypertensive rat model., PMID:30045361
Targeting transcriptional control of soluble guanylyl cyclase via NOTCH for prevention of cardiovascular disease., PMID:29754438
Cocoa procyanidins modulate transcriptional pathways linked to inflammation and metabolism in human dendritic cells., PMID:29714395
Phenotypic Consequences of a Genetic Predisposition to Enhanced Nitric Oxide Signaling., PMID:28982690
Reciprocal regulation between O-GlcNAcylation and tribbles pseudokinase 2 (TRIB2) maintains transformative phenotypes in liver cancer cells., PMID:27515988
Stimulators of the soluble guanylyl cyclase: promising functional insights from rare coding atherosclerosis-related GUCY1A3 variants., PMID:27342234
RNF213 as the major susceptibility gene for Chinese patients with moyamoya disease and its clinical relevance., PMID:27128593
Disrupted nitric oxide signaling due to GUCY1A3 mutations increases risk for moyamoya disease, achalasia and hypertension., PMID:26777256
Sildenafil treatment in vivo stimulates Leydig cell steroidogenesis via the cAMP/cGMP signaling pathway., PMID:20663985
Effect of paraquat exposure on nitric oxide-responsive genes in rat mesencephalic cells., PMID:20388547
For research use only. Not for human or drug use.
